Zobrazeno 1 - 4
of 4
pro vyhledávání: '"John P. Statz"'
Autor:
Junghyun Ryu, John P. Statz, William Chan, Kiana Oyama, Maggie Custer, Martin Wienisch, Richard Chen, Carol B. Hanna, Jon D. Hennebold
Publikováno v:
Cells, Vol 13, Iss 10, p 829 (2024)
Huntington’s disease (HD) arises from expanded CAG repeats in exon 1 of the Huntingtin (HTT) gene. The resultant misfolded HTT protein accumulates within neuronal cells, negatively impacting their function and survival. Ultimately, HTT accumulation
Externí odkaz:
https://doaj.org/article/aeabb05c2b7e4242af4b9567dccbd292
Autor:
Junghyun Ryu, John P. Statz, William Chan, Fernanda C. Burch, John V. Brigande, Beth Kempton, Edward V. Porsov, Lauren Renner, Trevor McGill, Benjamin J. Burwitz, Carol B. Hanna, Martha Neuringer, Jon D. Hennebold
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mutations in the MYO7A gene lead to Usher syndrome type 1B (USH1B), a disease characterized by congenital deafness, vision loss, and balance impairment. To create a nonhuman primate (NHP) USH1B model, CRISPR/Cas9 was used to disrupt MYO7A in
Externí odkaz:
https://doaj.org/article/5a7465c0a8444145a84a6c18f325d2dc
Autor:
Shivangi Nath, Kristen L. Fowler, Rangsun Parnpai, Brittany Gill, Michael A. White, Sujittra Khampang, Siran Tian, Krista M. Symosko, Alyse N. Steves, Jon D. Hennebold, Charles A. Easley, Jacqueline N. Langmo, Katherine Watkins Greeson, In Ki Cho, Kyle E. Orwig, Gerald Schatten, John P. Statz, Kanchana Punyawai, Calvin Simerly
Publikováno v:
F&S science
Objective To demonstrate that functional spermatids can be derived in vitro from nonhuman primate pluripotent stem cells. Design Green fluorescent protein-labeled, rhesus macaque nonhuman primate embryonic stem cells (nhpESCs) were differentiated int
Autor:
Michael T.J. Hague, J. Dylan Shropshire, Chelsey N. Caldwell, John P. Statz, Kimberly A. Stanek, William R. Conner, Brandon S. Cooper
Publikováno v:
Curr Biol
Endosymbioses influence host physiology, reproduction, and fitness, but these relationships require efficient microbe transmission between host generations to persist. Maternally transmitted Wolbachia are the most common known endosymbionts(1), but t