Zobrazeno 1 - 10
of 111
pro vyhledávání: '"John P. Spence"'
Autor:
W. Richard Burack, Janice M. Spence, John P. Spence, Stephen A. Spence, Philip J. Rock, Gautam N. Shenoy, Leonard D. Shultz, Richard B. Bankert, Steven H. Bernstein
Publikováno v:
Blood Advances, Vol 1, Iss 16, Pp 1263-1273 (2017)
Abstract: To discern features of non-Hodgkin lymphomas (NHL) that are autonomous from those that are shaped by the tumor environment (TE), we used patient-derived xenografts (PDX) to probe the effects on neoplastic cells of manipulating the TE. Prope
Externí odkaz:
https://doaj.org/article/17dc5aacbe05446cb7239a3cd9973875
Autor:
Carol Fries Simpson, Janice M Spence, Cameron Baker, Aayush Poudel, John P Spence, Philip J Rock, Hongyue Wang, Diana G Adlowitz, Helene R McMurray, Andrew McDavid, Richard Burack
Publikováno v:
Blood. 140:6363-6364
Autor:
Prerna Aneja, Thomas Kinna, Jacob Newman, Saber Sami, Joe Cassidy, Jordan McCarthy, Madhuri Tiwari, Aarti Kumar, John P. Spencer
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
Caregiver-infant interactions shape infants' early visual experience; however, there is limited work from low-and middle-income countries (LMIC) in characterizing the visual cognitive dynamics of these interactions. Here, we present an innovative dya
Externí odkaz:
https://doaj.org/article/18637aa43b404fcda6c16967e0231a11
Autor:
W. Richard Burack, Diana G Adlowitz, Philip J Rock, Carol Fries, John P. Spence, Janice M. Spence
Publikováno v:
Pediatr Blood Cancer
Acute lymphoblastic leukemia (ALL) is often composed of numerous subclones. Here we test whether the clonal composition of the blood is representative of the bone marrow at leukemia onset. Using ultra-deep IGH sequencing, we detected 28 clones across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9352b5a4bf6f446f7fa39aa8e23dc673
https://europepmc.org/articles/PMC7258142/
https://europepmc.org/articles/PMC7258142/
Autor:
Tiebing Liang, John P. Spence, Sha Cao, Jill L. Reiter, Kent E. Williams, Richard L. Bell, Dongbing Lai
Publikováno v:
Alcohol
Background Paternal alcohol abuse is a well-recognized risk factor for the development of an alcohol use disorder (AUD). In addition to genetic and environmental risk factors, heritable epigenetic factors also have been proposed to play a key role in
Autor:
Stephen A. Spence, Steven H. Bernstein, Richard B. Bankert, Leonard D. Shultz, W. Richard Burack, Janice M. Spence, Gautam N Shenoy, Philip J Rock, John P. Spence
Publikováno v:
Blood Advances. 1:1263-1273
To discern features of non-Hodgkin lymphomas (NHL) that are autonomous from those that are shaped by the tumor environment (TE), we used patient-derived xenografts (PDX) to probe the effects on neoplastic cells of manipulating the TE. Properties of n
Autor:
John P. Spence, Tiebing Liang, Weidong Yong, Yi Zou, Hao Gu, Tamara Graves, Kent E. Williams, Zhao Lai, Bin Qiu, Jill L. Reiter, Lingling Zhang, Dawn Garcia, Paula J. Bice
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics, Vol 9 (2018)
Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female animals frequently drink more th
Autor:
Matthew R. Allen, John P. Spence, Aaron E. Carroll, Jennifer L. Buddenbaum, Christina R. Santangelo
Publikováno v:
Journal of Clinical and Translational Science. 5:64-64
IMPACT: The Independent Investigator Incubator program provides 1:1 mentoring from ‘super-mentors’ to enhance junior faculty careers in research. OBJECTIVES/GOALS: In 2014, the Indiana University School of Medicine (IUSM) in collaboration with th
Publikováno v:
BMC Medical Education
BMC Medical Education, Vol 18, Iss 1, Pp 1-11 (2018)
BMC Medical Education, Vol 18, Iss 1, Pp 1-11 (2018)
Background In the highly competitive environment of academic medicine, junior faculty investigators face high attrition rates due to challenges in finding effective mentorship, securing grant funding, and obtaining resources to support their career d
Autor:
Philip J Rock, Carol Fries, Diana G Adlowitz, John P. Spence, Richard Burack, Janice M. Spence
Publikováno v:
Blood. 134:3955-3955
Background: Recombination-activating gene (RAG) mediates recombination of the immunoglobulin heavy chain variable gene (IGHV) in immature B lymphocytes. Aberrant targeting of RAG to non-IGH sites in B cell acute lymphoblastic leukemia (B-ALL) contrib