Zobrazeno 1 - 10
of 11
pro vyhledávání: '"John P. Rohde"'
Autor:
Karla N. Valenzuela-Valderas, Elmira Farrashzadeh, Yuen-Yan Chang, Yunnuo Shi, Renee Raudonis, Brendan M. Leung, John R. Rohde, Jost Enninga, Zhenyu Cheng
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108216- (2023)
Summary: Shigella flexneri is an intracellular bacterium that hijacks the host actin cytoskeleton to invade and disseminate within the colonic epithelium. Shigella’s virulence factors induce actin polymerization, leading to bacterial uptake, actin
Externí odkaz:
https://doaj.org/article/d81c40cbe4534cef807b4c9dc65e24cc
Autor:
Timurs Maculins, Erik Verschueren, Trent Hinkle, Meena Choi, Patrick Chang, Cecile Chalouni, Shilpa Rao, Youngsu Kwon, Junghyun Lim, Anand Kumar Katakam, Ryan C Kunz, Brian K Erickson, Ting Huang, Tsung-Heng Tsai, Olga Vitek, Mike Reichelt, Yasin Senbabaoglu, Brent Mckenzie, John R Rohde, Ivan Dikic, Donald S Kirkpatrick, Aditya Murthy
Publikováno v:
eLife, Vol 10 (2021)
Defective autophagy is strongly associated with chronic inflammation. Loss-of-function of the core autophagy gene Atg16l1 increases risk for Crohn’s disease in part by enhancing innate immunity through myeloid cells such as macrophages. However, au
Externí odkaz:
https://doaj.org/article/f7e6c7d1cf284be89aa3c3ebd2cb98db
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 59 (2021)
Group I chaperonins are a highly conserved family of essential proteins that self-assemble into molecular nanoboxes that mediate the folding of cytoplasmic proteins in bacteria and organelles. GroEL, the chaperonin of Escherichia coli, is the archety
Externí odkaz:
https://doaj.org/article/5f4b02a398a541d98eb6c17be5591264
Autor:
Ryan G. Gaudet, Cynthia X. Guo, Raphael Molinaro, Haila Kottwitz, John R. Rohde, Anne-Sophie Dangeard, Cécile Arrieumerlou, Stephen E. Girardin, Scott D. Gray-Owen
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1418-1430 (2017)
Intestinal epithelial cells (IECs) act as sentinels for incoming pathogens. Cytosol-invasive bacteria, such as Shigella flexneri, trigger a robust pro-inflammatory nuclear factor κB (NF-κB) response from IECs that is believed to depend entirely on
Externí odkaz:
https://doaj.org/article/87f0ff614cc546fd974eada382523798
Publikováno v:
Marine Drugs, Vol 17, Iss 5, p 307 (2019)
Pseudomonas aeruginosa biofilms are typically associated with the chronic lung infection of cystic fibrosis (CF) patients and represent a major challenge for treatment. This opportunistic bacterial pathogen secretes alginate, a polysaccharide that is
Externí odkaz:
https://doaj.org/article/0390d41bf51e4fd0b53e6cecfe8fd27f
Publikováno v:
Western Journal of Emergency Medicine, Vol 14, Iss 5, Pp 477-481 (2013)
Introduction: Academic departments of emergency medicine are becoming increasingly involved in assisting with the development of long-term emergency medicine training programs in low and middle-income countries. This article presents our 10-year expe
Externí odkaz:
https://doaj.org/article/9aa95ac06fe342d9aabcfd80f728f2c4
Autor:
Emma C L Finlayson-Trick, Landon J Getz, Patrick D Slaine, Mackenzie Thornbury, Emily Lamoureux, Jamie Cook, Morgan G I Langille, Lois E Murray, Craig McCormick, John R Rohde, Zhenyu Cheng
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189404 (2017)
Host diet influences the diversity and metabolic activities of the gut microbiome. Previous studies have shown that the gut microbiome provides a wide array of enzymes that enable processing of diverse dietary components. Because the primary diet of
Externí odkaz:
https://doaj.org/article/db0953e440e440388c5a120ef4b83bde
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122585 (2015)
Shigellosis is a severe diarrheal disease that affects hundreds of thousands of individuals resulting in significant morbidity and mortality worldwide. Shigellosis is caused by Shigella spp., a gram-negative bacterium that uses a Type 3 Secretion Sys
Externí odkaz:
https://doaj.org/article/33f70617786141358424ed1d836e3367
Autor:
Jon Huibregtse, John R Rohde
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004255 (2014)
Externí odkaz:
https://doaj.org/article/298192953f3148d1b218c12b76e962dc
Autor:
Ian Jones, Tyler W. Barrett, Corey M. Slovis, Stephan Russ, John P. Rohde, Austin T. Smith, Keith D Wrenn, Wesley H. Self
Publikováno v:
The American Journal of Emergency Medicine. 35:377.e1-377.e2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ec057043d77e17955e96fa24bfe004
https://doi.org/10.1016/j.ajem.2016.08.024
https://doi.org/10.1016/j.ajem.2016.08.024