Zobrazeno 1 - 10
of 135
pro vyhledávání: '"John P. Rapp"'
Autor:
John P. Rapp, Bina Joe
Publikováno v:
Comprehensive Physiology
Advances in molecular genetics have provided well-defined physical genetic maps and large numbers of genetic markers for both model organisms and humans. It is now possible to gain a fundamental understanding of the genetic architecture underlying qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3887d1bbe8df10f82aa18e5ce0bf9dc
https://pubmed.ncbi.nlm.nih.gov/31688958
https://pubmed.ncbi.nlm.nih.gov/31688958
Autor:
Michael R. Garrett, John P. Rapp
Publikováno v:
Am J Physiol Renal Physiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1759cbbb4edf56edda57d3a6ce83954
https://pubmed.ncbi.nlm.nih.gov/31545925
https://pubmed.ncbi.nlm.nih.gov/31545925
Publikováno v:
Hypertension.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd5d20753c01265f21d8d2fd7ceb110b
https://doi.org/10.1161/01.hyp.0000187510.46439.57
https://doi.org/10.1161/01.hyp.0000187510.46439.57
Autor:
John P. Rapp
Publikováno v:
Physiological Genomics. 45:737-750
There is a significant literature describing quantitative trait loci (QTL) controlling blood pressure (BP) in the Dahl salt-sensitive (S) rat. In studies to identify the genes underlying BP QTL it has been common practice to place chromosomal segment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a928a9f7206025badcf3d910dfa65518
https://doi.org/10.1152/physiolgenomics.00046.2013
https://doi.org/10.1152/physiolgenomics.00046.2013
Autor:
Ashley C. Johnson, Jonathan D. Fratkin, Michael R. Garrett, Zaliya Morris, Xuexiang Wang, John P. Rapp, Jonathan W. Lee, Elise P. Gomez-Sanchez, Ashlyn C Harmon
Publikováno v:
Mammalian Genome. 24:95-104
Cataracts are a major cause of blindness. The most common forms of cataracts are age- and UV-related and develop mostly in the elderly, while congenital cataracts appear at birth or in early childhood. The Dahl salt-sensitive (SS/Jr) rat is an extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74bae1853842f7b8f004f9c96211956
https://doi.org/10.1007/s00335-013-9447-1
https://doi.org/10.1007/s00335-013-9447-1
The Dahl salt-sensitive rat is one of the principal animal models of hereditary hypertension. Genome-wide searches were undertaken to detect quantitative trait loci (QTLs) that influence blood pressure, cardiac mass, and body weight in four F2 popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64755c2d10d1373d956ef7c805f3ffa
https://ora.ox.ac.uk/objects/uuid:31b9afb5-0675-433e-8f2f-237de5bec4b3
https://ora.ox.ac.uk/objects/uuid:31b9afb5-0675-433e-8f2f-237de5bec4b3
Publikováno v:
Hypertension. 45:451-459
Previously, a blood pressure (BP) quantitative trait locus (QTL) on rat chromosome 9 (RNO9) was localized to a Resp18 ), which also mapped in the 2.4-cM BP QTL interval. Additional substitution mapping located the QTL to Resp18 . Nucleotide variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242acc4f73966eb696b10c624d314e17
https://doi.org/10.1161/01.hyp.0000154678.64340.7f
https://doi.org/10.1161/01.hyp.0000154678.64340.7f
Publikováno v:
Journal of Hypertension. 21:2077-2084
OBJECTIVE To improve the localization of a blood pressure quantitative trait locus (BP QTL) on rat chromosome (RNO) 1. METHODS Congenic substrains were derived from the progenitor congenic strains S.LEW(D1Mco4X1) and S.LEW(D1Mco4X5) which previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d39102c95cfd3537543971dfc05fb3b
https://doi.org/10.1097/00004872-200311000-00017
https://doi.org/10.1097/00004872-200311000-00017
Publikováno v:
Journal of the American Society of Nephrology. 14:1175-1187
The Dahl salt-sensitive hypertensive (S) rat develops albuminuria early in life even on a low-salt diet. In contrast, the spontaneously hypertensive rat (SHR) is highly resistant to developing albuminuria despite elevated BP. An F(1) hybrid of S and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e6852b5a936d51dbd00554d1c87d14
https://doi.org/10.1097/01.asn.0000060572.13794.58
https://doi.org/10.1097/01.asn.0000060572.13794.58
Autor:
Michael R. Garrett, John P. Rapp
Publikováno v:
Mammalian Genome. 14:268-273
Previously we reported that there is a blood pressure quantitative trait locus (QTL) on rat Chromosome (Chr) 7 seen when comparing Dahl salt-sensitive (S) rats and Dahl salt-resistant (R) rats. Evidence was also presented that this QTL was due to gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf05d5b0d1dd044d6037fb9b4e9c5029
https://doi.org/10.1007/s00335-002-2245-9
https://doi.org/10.1007/s00335-002-2245-9