Zobrazeno 1 - 10
of 27
pro vyhledávání: '"John P. Mathias"'
Autor:
Mam Y Mboge, Zhijuan Chen, Alyssa Wolff, John V Mathias, Chingkuang Tu, Kevin D Brown, Murat Bozdag, Fabrizio Carta, Claudiu T Supuran, Robert McKenna, Susan C Frost
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207417 (2018)
Carbonic anhydrases (CAs) have been linked to tumor progression, particularly membrane-bound CA isoform IX (CA IX). The role of CA IX in the context of breast cancer is to regulate the pH of the tumor microenvironment. In contrast to CA IX, expressio
Externí odkaz:
https://doaj.org/article/57c7274cabf84022a0841512b8b5930b
Autor:
Agustin Casimiro-Garcia, Christophe Allais, Agnes Brennan, Chulho Choi, Gabriela Dower, Kathleen A. Farley, Margaret Fleming, Andrew Flick, Richard K. Frisbie, Justin Hall, David Hepworth, Hannah Jones, John D. Knafels, Steve Kortum, Frank E. Lovering, John P. Mathias, Sashi Mohan, Paul M. Morgan, Chuenlei Parng, Kevin Parris, Nick Pullen, Franklin Schlerman, John Stansfield, Joseph W. Strohbach, Felix F. Vajdos, Fabien Vincent, Hong Wang, Xiaolun Wang, Robert Webster, Stephen W. Wright
Publikováno v:
Journal of medicinal chemistry. 65(1)
A diaryl ketone series was identified as vanin-1 inhibitors from a high-throughput screening campaign. While this novel scaffold provided valuable probe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d147fed656ddd3e967c8652323e02bae
https://pubmed.ncbi.nlm.nih.gov/34967602
https://pubmed.ncbi.nlm.nih.gov/34967602
Publikováno v:
The Journal of Organic Chemistry. 64:8256-8262
The reaction of 1,3-diphenyl-2-propenyl acetate (9) with dimethylmalonate to give the substitution product 10 is effectively catalyzed by Pd complexes containing chiral imine-sulfide chelate ligands derived from amino acids. The ligand of choice, (S)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000dd2c9f80175dd3d2c8e205a0ccb51
https://doi.org/10.1021/jo9910177
https://doi.org/10.1021/jo9910177
Publikováno v:
Tetrahedron: Asymmetry. 9:753-756
A new series of sulfur–imine mixed donor chiral ligands, prepared in only two steps from commercially available ( S )-valinol, have been shown to give up to 94% enantiomeric excess in a palladium-catalysed allylic substitution reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95ddc6c40a180589c4603893e724be5f
https://doi.org/10.1016/s0957-4166(98)00057-3
https://doi.org/10.1016/s0957-4166(98)00057-3
Autor:
Dana M. Gordon, Christopher T. Seto, George M. Whitesides, John P. Mathias, Donovan N. Chin, Mathai Mammen, Eric E. Simanek
Publikováno v:
Accounts of Chemical Research. 28:37-44
A molecule is usually understood to be a stable collection of atoms connected bv a continuous network of covalent bonds. The develipment of methods for constructing these networks has been a central occupation of organic chemistry, and the success of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c74914b333aa9fe4df660b1d865044
https://doi.org/10.1021/ar00049a006
https://doi.org/10.1021/ar00049a006
Publikováno v:
The Journal of Organic Chemistry. 59:4904-4909
Variable-temperature lH NMR spectroscopy of the region between 13 and 16 ppm can be used in the conformational analysis of hydrogen-bonded aggregates comprising 1 equiv-of a trismelamine (hub(M)s) and 3 equiv of an isocyanuric acid (CA). T*o typer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94d6041526c11997e1d95103b15128cf
https://doi.org/10.1021/jo00096a037
https://doi.org/10.1021/jo00096a037
Publikováno v:
Journal of the American Chemical Society. 116:4326-4340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b02b6ab96d7737df08ade67f669f0c1
https://doi.org/10.1021/ja00089a022
https://doi.org/10.1021/ja00089a022
Autor:
Christopher T. Seto, John P. Mathias, George M. Whitesides, Jonathan A. Zerkowski, Eric E. Simanek
Publikováno v:
Journal of the American Chemical Society. 116:4316-4325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f53544e34cae4d4da4d8ff73ddd3baff
https://doi.org/10.1021/ja00089a021
https://doi.org/10.1021/ja00089a021
Publikováno v:
Journal of the American Chemical Society. 116:4305-4315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6646ff1d6d60413d9702e2bee9d52c36
https://doi.org/10.1021/ja00089a020
https://doi.org/10.1021/ja00089a020
Publikováno v:
Journal of the American Chemical Society. 116:1725-1736
Reaction of hub(MM) 3 , a compound containing six melamines, with monomeric, dimeric, and trimeric derivatives of isocyanuric acid yields three new types of hydrogen-bonded self-assembled supramolecular aggregates. These new aggregates are represente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cbb3d83dd694be152087321b879f8fc
https://doi.org/10.1021/ja00084a013
https://doi.org/10.1021/ja00084a013