Zobrazeno 1 - 10 of 56 pro vyhledávání: '"John P. Mackintosh"'
1
Akademický článek
A vexing case of a 73‐year‐old man with fevers, orbital cellulitis, and asymptomatic interstitial lung disease
Autor: Sushil Agwan, Lai‐Ying Zhang, Thomas Baker, Michael Lane, David Godbolt, John A. Mackintosh
Publikováno v: Respirology Case Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract VEXAS (Vacuoles, E1 enzyme, X‐linked, Autoinflammatory, Somatic) syndrome is a rare and recently identified disease resulting from a somatic mutation in the X‐linked UBA1 gene in cells of myeloid lineage. It can present in a myriad of wa
Externí odkaz: https://doaj.org/article/0de0aa8486ae4532b956f3d972e8b379
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2
Akademický článek
Telomere biology disorder presenting acutely with pulmonary fibrosis and hepatopulmonary syndrome in a young adult male
Autor: Samantha Chin‐Yun Kung, Olivia Dixon, Sarah Kentwell, Raja S. Vasireddy, Jonathan Rodgers, Yuming Ding, Tony Rahman, Caroline Tallis, Ian A. Yang, John A. Mackintosh
Publikováno v: Respirology Case Reports, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract A 33‐year‐old man presented with acute dyspnoea and profound hypoxaemia, and had clubbing, greying of hair, orthodeoxia and fine inspiratory crackles. CT chest showed established pulmonary fibrosis in a usual interstitial pneumonia patte
Externí odkaz: https://doaj.org/article/4f005229bf8e49679982419de20a0c87
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4
Akademický článek
Interstitial pneumonia with autoimmune features: challenges and controversies
Autor: John A. Mackintosh, Athol U. Wells, Vincent Cottin, Andrew G. Nicholson, Elisabetta A. Renzoni
Publikováno v: European Respiratory Review, Vol 30, Iss 162 (2021)
The presence of clinical, serological and/or radiological features suggestive, but not confirmatory, of a defined connective tissue disease in patients with interstitial lung disease is a relatively frequent occurrence. In 2015, the European Respirat
Externí odkaz: https://doaj.org/article/70b74619c4c04d038e5ded7ac8303f5f
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5
Akademický článek
Airway Telomere Length in Lung Transplant Recipients
Autor: John A. Mackintosh, Stephanie T. Yerkovich, Maxine E. Tan, Luke Samson, Peter MA Hopkins, Daniel C. Chambers
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
IntroductionChronic lung allograft dysfunction (CLAD) represents the major impediment to long term survival following lung transplantation. Donor and recipient telomere length have been shown to associate with lung transplant outcomes, including CLAD
Externí odkaz: https://doaj.org/article/8e8000e7deb044489c76ac1ae51634ad
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6
Akademický článek
TELO-SCOPE study: a randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis
Autor: Tamera J Corte, Adam Jaffe, Christopher Grainge, Jeremy Wrobel, Hiran Selvadurai, Stephanie T Yerkovich, Daniel C Chambers, Maxine Tan, Ian Glaspole, Peter Hopkins, Paul N Reynolds, Hilda A Pickett, Nicole S Goh, John A Mackintosh, Maria Pietsch, Viviana Lutzky, Debra Enever, Sandra Bancroft, Simon H Apte, Joanne L Dickinson
Publikováno v: BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Introduction Recent discoveries have identified shortened telomeres and related mutations in people with pulmonary fibrosis (PF). There is evidence to suggest that androgens, including danazol, may be effective in lengthening telomeres in peripheral
Externí odkaz: https://doaj.org/article/d78f24442db3416a88dff94c49697f59
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