Zobrazeno 1 - 10
of 140
pro vyhledávání: '"John P. M. Wood"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Retinal detachment is a sight-threatening disorder, which occurs when the photoreceptors are separated from their vascular supply. The aim of the present study was to shed light on photoreceptor energy metabolism during experimental detachment in rat
Externí odkaz:
https://doaj.org/article/11282eb7a4ec43578efa43f5b70f4ab7
Autor:
Robert J. Casson, John P. M. Wood, Jack Ao, Jagjit S. Gilhotra, Shane R. Durkin, James Muecke, WengOnn Chan, Glyn Chidlow
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 2, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/f690866a6f014552bf76d90ae8b43538
Publikováno v:
BMC Neuroscience, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background The Pde6brd1 (Rd1) mouse is widely used as a murine model for human retinitis pigmentosa. Understanding the spatio-temporal patterns of cone degeneration is important for evaluating potential treatments. In the present study we pe
Externí odkaz:
https://doaj.org/article/6b0ea6d24a86451783ab8c4250639f47
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Recent studies suggest cone degeneration in retinitis pigmentosa (RP) may result from intracellular energy depletion. We tested the hypothesis that cones die when depleted of energy by examining the effect of two bioenergetic, nutraceutical agents on
Externí odkaz:
https://doaj.org/article/d7edd97d33294ab88b0673946e6e97bc
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
The vascular hypothesis of glaucoma proposes that retinal ganglion cell axons traversing the optic nerve head (ONH) undergo oxygen and nutrient insufficiency as a result of compromised local blood flow, ultimately leading to their degeneration. To da
Externí odkaz:
https://doaj.org/article/d371aa1df45d4112bb43580a6e4c777c
Autor:
Luke A. Halliday, John P. M. Wood, Glyn Chidlow, Robert J. Casson, Dinesh Selva, Michelle T. Sun
Publikováno v:
Eye. 37:62-68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c1161c88106e9639b8068e10b76c62
https://doi.org/10.1038/s41433-021-01872-9
https://doi.org/10.1038/s41433-021-01872-9
Autor:
John P. M. Wood, Glyn Chidlow, Luke A. Halliday, Robert J. Casson, Dinesh Selva, Michelle Sun
Publikováno v:
Translational vision sciencetechnology. 11(11)
The purpose of this study was to determine whether rodent lacrimal glands (LGs) represent a suitable surrogate for human tissue in bio-engineering research, we undertook a meticulous histological and histochemical comparison of these two tissues.Hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0197d8be52461a3165d1fff59ce0c9
https://pubmed.ncbi.nlm.nih.gov/36374486
https://pubmed.ncbi.nlm.nih.gov/36374486
Publikováno v:
Clinical & Experimental Ophthalmology. 49:454-469
Background To treat healthy retinal pigmented epithelium (RPE) with the 3-ns retinal rejuvenation therapy (2RT) laser and to investigate the subsequent wound-healing response of these cells. Methods Primary rat RPE cells were treated with the 2RT las
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4e0d52b0a5a5ca7a06ab7e7d17bfe6
https://doi.org/10.1111/ceo.13931
https://doi.org/10.1111/ceo.13931
Autor:
Dennis H. Lau, John W. Finnie, Muayad Alasady, Krupesh P. Patel, Rajiv Mahajan, John P. M. Wood, Jonathan M. Kalman, Prashanthan Sanders, Nicholas J. Shipp, Anthony G. Brooks, Jim Manavis, Chrishan S. Samuel
Publikováno v:
JACC: Clinical Electrophysiology. 7:630-641
Objectives This study sought to evaluate the effect of weight loss on the atrial substrate for atrial fibrillation (AF). Background Whether weight loss can reverse the atrial substrate of ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e36956f5fe6535d34641d448e8ae489
https://doi.org/10.1016/j.jacep.2020.11.015
https://doi.org/10.1016/j.jacep.2020.11.015
Autor:
Glyn Chidlow, Simon W. M. John, Jeffrey M. Harder, Evangelia Daskalaki, Peter A. Williams, Nicole E. Foxworth, Craig E. Wheelock, Tionna B Ouellette, Robert J Casson, Chelsea Guymer, John P. M. Wood, Chi Zhang, Brynn H Cardozo, Christa Montgomery, Kelly E Deering, Revathi Balasubramanian
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Age-related bioenergetic insufficiency increases the vulnerability of retinal ganglion cells to intraocular pressure during glaucoma pathogenesis. This paper addresses these relationships and provides a deeper understanding of this commo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f090f275df2db2821fdf8d2ab659d2f
http://europepmc.org/articles/PMC7776900
http://europepmc.org/articles/PMC7776900