Zobrazeno 1 - 10
of 60
pro vyhledávání: '"John P. Leader"'
Autor:
Michael J. Jennings, Timothy C. A. Molteno, Robert J. Walker, Jennifer J. Bedford, John P. Leader, Tony Poole
Publikováno v:
Data, Vol 6, Iss 11, p 118 (2021)
The primary cilium has recently become the focus of intensive investigations into understanding the physical structure and processes of eukaryotic cells. This paper describes two tilt-series image datasets, acquired by transmission electron microscop
Externí odkaz:
https://doaj.org/article/440750d14c2844c6872880efaa8a42be
Autor:
Mark M. James, John Francis Leader
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
The COVID-19 pandemic led to social restrictions that often prevented us from hugging the ones we love. This absence helped some realize just how important these interactions are to our sense of care and connection. Many turned to digitally mediated
Externí odkaz:
https://doaj.org/article/86cada37ebc0472090f4cf505a459435
Publikováno v:
American Journal of Physiology-Cell Physiology. 322:C1151-C1165
We endeavored to understand the factors determining the peak force-resting membrane potential ( EM) relationships of isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles from mice (25°C), especially in relation to fati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbba349b6b62c04b722fb82d9c94a2ca
https://doi.org/10.1152/ajpcell.00401.2021
https://doi.org/10.1152/ajpcell.00401.2021
Autor:
John P. Leader, Michael J. Jennings, Jennifer J. Bedford, Robert J. Walker, T. C. A. Molteno, Tony Ca Poole
Publikováno v:
Data, Vol 6, Iss 118, p 118 (2021)
The primary cilium has recently become the focus of intensive investigations into understanding the physical structure and processes of eukaryotic cells. This paper describes two tilt-series image datasets, acquired by transmission electron microscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08d150a76af8d2f8a48bd8c5f0c15aa
https://www.mdpi.com/2306-5729/6/11/118
https://www.mdpi.com/2306-5729/6/11/118
Autor:
Amanda Higgins, John P. Leader, Denis S. Loiselle, Simeon P. Cairns, Wei Lin, Jean-Marc Renaud
Publikováno v:
Journal of Applied Physiology. 118:662-674
We examined whether a Ca2+-K+ interaction was a potential mechanism operating during fatigue with repeated tetani in isolated mouse muscles. Raising the extracellular Ca2+ concentration ([Ca2+]o) from 1.3 to 10 mM in K+-depressed slow-twitch soleus a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0968afb4118198d6a494033c4282328d
https://doi.org/10.1152/japplphysiol.00705.2013
https://doi.org/10.1152/japplphysiol.00705.2013
Publikováno v:
Annals of Translational Medicine. 7:S332-S332
It is now more than fifty years since Burg made a signal advance in the study of renal physiology by reporting a method of isolating and perfusing tubules from selected regions of the kidney (1). Prior to this, knowledge of renal tubular function had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d54e9fc9831bb5c5ddc3d86ffd9ab9a
https://doi.org/10.21037/atm.2019.09.120
https://doi.org/10.21037/atm.2019.09.120
Publikováno v:
Nephrology (Carlton, Vic.). 23(1)
Aim Long-term administration of lithium has been associated with the development of a chronic interstitial fibrosis in addition to nephrogenic diabetes insipidus (NDI). Earlier studies have demonstrated that amiloride, by blocking the epithelial sodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc47aae0bbc27cc9961275b580369e6
https://pubmed.ncbi.nlm.nih.gov/27682266
https://pubmed.ncbi.nlm.nih.gov/27682266
Autor:
Robert J. Walker, Hans-Peter Marti, Catherine J Leader, Andreas Scherer, Jennifer J. Bedford, Aaron Jeffs, John P. Leader
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0168240 (2016)
PLoS ONE, Vol 11, Iss 12, p e0168240 (2016)
Accurate diagnosis of fibrosis is of paramount clinical importance. A human fibrosis classifier based on metzincins and related genes (MARGS) was described previously. In this investigation, expression changes of MARGS genes were explored and evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfdf0b79750b42aa64d6c02f52d2826
https://pubmed.ncbi.nlm.nih.gov/28002484
https://pubmed.ncbi.nlm.nih.gov/28002484
Autor:
Michael P. O'Donnell, John P. Leader
Publikováno v:
Archives of Insect Biochemistry and Physiology. 63:123-134
The effects of stimulants of fluid secretion on net transepithelial transport of the MRP2 substrate Texas Red and the p-glycoprotein substrate daunorubicin were examined in Malpighian tubules of Drosophila melanogaster. Fluid secretion rates were det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad74ec4d9b7280be950a2f6ba335baf8
https://doi.org/10.1002/arch.20148
https://doi.org/10.1002/arch.20148
Autor:
Michael P. O'Donnell, John P. Leader
Publikováno v:
Journal of Experimental Biology. 208:4363-4376
SUMMARYTransport of fluorescent substrates of p-glycoprotein (P-gp) and multidrug resistance-associated protein 2 (MRP2) by insect Malpighian tubules was examined using confocal laser scanning microscopy (CLSM). Isolated tubules of the cricket Teleog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cc2601371815291ccc6f2dfea4e8e0
https://doi.org/10.1242/jeb.01911
https://doi.org/10.1242/jeb.01911