Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John P. Leach"'
Autor:
Fabian L. Cardenas-Diaz, Derek C. Liberti, John P. Leach, Apoorva Babu, Jonathan Barasch, Tian Shen, Maria A. Diaz-Miranda, Su Zhou, Yun Ying, Danielle A. Callaway, Michael P. Morley, Edward E. Morrisey
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112451- (2023)
Summary: Alveolar epithelial type 2 (AT2) cells harbor the facultative progenitor capacity in the lung alveolus to drive regeneration after lung injury. Using single-cell transcriptomics, software-guided segmentation of tissue damage, and in vivo mou
Externí odkaz:
https://doaj.org/article/4e618927980d43068b36d605302b2cf2
Autor:
Rebecca Windmueller, John P. Leach, Apoorva Babu, Su Zhou, Michael P. Morley, Aoi Wakabayashi, Nataliya B. Petrenko, Patrick Viatour, Edward E. Morrisey
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 3105-3116.e4 (2020)
Summary: The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more r
Externí odkaz:
https://doaj.org/article/4cc9d514ae934b469d3b2fc8c7e2809f
Autor:
James W. Mitchell, Adam Noble, Gus Baker, Rachel Batchelor, Francesco Brigo, Jakob Christensen, Jacqueline French, Antonio Gil-Nagel, Alla Guekht, Nathalie Jette, Reetta Kälviäinen, John Paul Leach, Melissa Maguire, Terence O’Brien, Felix Rosenow, Philippe Ryvlin, Phil Tittensor, Manjari Tripathi, Eugen Trinka, Samuel Wiebe, Paula R. Williamson, Tony Marson
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background A Core Outcome Set (COS) is a standardised list of outcomes that should be reported as a minimum in all clinical trials. In epilepsy, the choice of outcomes varies widely among existing studies, particularly in clinical trials. Th
Externí odkaz:
https://doaj.org/article/ea6743552dd24e56831464c47d62202f
Autor:
Rachael Wood, Marion Bennie, John Paul Leach, Gavin MacColl, Stuart McTaggart, Karen Gronkowski
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Objective To examine the impact of Medicines and Healthcare products Regulatory Agency (MHRA) safety alerts on valproate prescribing among women aged 14–45 years in Scotland and examine trends in pregnancies exposed to valproate.Design Population-b
Externí odkaz:
https://doaj.org/article/dcfc4701ae8240f89d82d5de6cf0a640
Autor:
Anthony G Marson, Girvan Burnside, Richard Appleton, Dave Smith, John Paul Leach, Graeme Sills, Catrin Tudur-Smith, Catrin O Plumpton, Dyfrig A Hughes, Paula R Williamson, Gus Baker, Silviya Balabanova, Claire Taylor, Richard Brown, Dan Hindley, Stephen Howell, Melissa Maguire, Rajiv Mohanraj, Philip EM Smith
Publikováno v:
Health Technology Assessment, Vol 25, Iss 75 (2021)
Background: Levetiracetam (Keppra®, UCB Pharma Ltd, Slough, UK) and zonisamide (Zonegran®, Eisai Co. Ltd, Tokyo, Japan) are licensed as monotherapy for focal epilepsy, and levetiracetam is increasingly used as a first-line treatment for generalised
Externí odkaz:
https://doaj.org/article/a6bb255ed29d423996d9ff3ae50435f9
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Objective To measure Differential Attainment (DA) among Scottish medical students and to explore whether attainment gaps increase or decrease during medical school.Design A retrospective analysis of undergraduate medical student performance on writte
Externí odkaz:
https://doaj.org/article/b6ed3ab5a431420d9cdabb87ef864421
Autor:
Girvan Burnside, Munir Pirmohamed, Anthony Guy Marson, John Paul Leach, Gus Baker, Catrin Tudur-Smith, Richard Appleton, Silviya Balabanova, Graeme Sills, Catrin Plumpton
Publikováno v:
BMJ Open, Vol 10, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/541ff5dc48e5411788ae6c76f19c71fa
Autor:
Aishan Patil, John P Leach
Publikováno v:
International Journal of Head and Neck Surgery. 13:92-97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8fa2b64189e0d91957103683e0ab8f6
https://doi.org/10.5005/jp-journals-10001-1529
https://doi.org/10.5005/jp-journals-10001-1529
Autor:
Jeremy Katzen, Luis Rodriguez, Yaniv Tomer, Apoorva Babu, Ming Zhao, Aditi Murthy, Paige Carson, Matthew Barrett, Maria C. Basil, Justine Carl, John P. Leach, Michael Morley, Matthew D. McGraw, Surafel Mulugeta, Timothy Pelura, Glenn Rosen, Edward E. Morrisey, Michael F. Beers
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
Disruption of alveolar type 2 cell (AEC2) protein quality control has been implicated in chronic lung diseases, including pulmonary fibrosis (PF). We previously reported the in vivo modeling of a clinical surfactant protein C (SP-C) mutation that led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec8843e7364e236c11b6a7d03444c39
https://pubmed.ncbi.nlm.nih.gov/36252035
https://pubmed.ncbi.nlm.nih.gov/36252035
Autor:
Frances L. Chen, Eva M. Oxford, Shao-Pei Chou, Na Li, John P. Leach, Sienna K. Perry, Bhargav D. Sanketi, Christina Cong, Sophie A. Kupiec-Weglinski, Rebecca Dubowitz, Erin Daugherity, James F. Martin, Charles G. Danko, Natasza A. Kurpios
RationaleThe most significantly associated atrial fibrillation (AF) risk loci in humans map to a noncoding gene desert upstream of the evolutionarily conserved left-right (LR) transcription factor Pitx2, a master regulator of LR asymmetric organ deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ada7a1701e1802800399543c779ff5
https://doi.org/10.1101/2022.09.20.508562
https://doi.org/10.1101/2022.09.20.508562
