Zobrazeno 1 - 10
of 86
pro vyhledávání: '"John P. Horn"'
Autor:
Paul H. M. Kullmann, John P. Horn
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Neurons in paravertebral sympathetic ganglia are innervated by converging nicotinic synapses of varying strength. Based upon intracellular recordings of excitatory postsynaptic potentials (EPSPs) with sharp microelectrodes these synapses were classif
Externí odkaz:
https://doaj.org/article/fabaf0cf0d644c4f9c5ca8318409a131
Autor:
Jingjun Wang, Mary E. Ritchey, Kamika Reynolds, Madeleine Carbonneau, Adam Carrera, Noelia Goti, John R. Horn, Cynthia J. Girman
Publikováno v:
Drugs - Real World Outcomes, Vol 10, Iss 3, Pp 439-446 (2023)
Abstract Background Patients with overactive bladder (OAB) experience sudden, intense urges to urinate, which may include urge urinary incontinence and nocturia. Pharmacotherapy includes β3-adrenergic receptor agonists such as mirabegron; however, m
Externí odkaz:
https://doaj.org/article/1d79bf1b904046eebf3537d3a5b48742
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Sascha Dublin, Sophie P. Chung, John R. Horn, Kacie F. Bogar, Charles E. Leonard
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 2, Pp 326-337 (2023)
Abstract Antidepressants are associated with traumatic injury and are widely used with other medications. It remains unknown how drug–drug–drug interactions (3DIs) between antidepressants and two other drugs may impact potential injury risks asso
Externí odkaz:
https://doaj.org/article/2b2adebda87e4a949890c4d970be9f12
Autor:
Mary E. Ritchey, Jingjun Wang, Jessica C. Young, Rajat Chandra, Adam Carrera, Noelia Goti, John R. Horn, Cynthia J. Girman
Publikováno v:
Drugs - Real World Outcomes, Vol 10, Iss 1, Pp 119-129 (2022)
Abstract Background Overactive bladder (OAB) is characterized by the presence of bothersome urinary symptoms. Pharmacologic treatment options for OAB include anticholinergics and β3-adrenergic agonists. Use of β3-adrenergic agonists may result in s
Externí odkaz:
https://doaj.org/article/210d52b5326c4be88f4630bc3d3b32cf
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Emily K. Acton, Warren B. Bilker, Sophie P. Chung, Ghadeer K. Dawwas, John R. Horn, Todd A. Miano, Thanh Phuong Pham Nguyen, Charles E. Leonard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Drug interactions involving benzodiazepines and related drugs (BZDs) are increasingly recognized as a contributor to increased risk of unintentional traumatic injury. Yet, it remains unknown to what extent drug interaction triads (3DIs) may
Externí odkaz:
https://doaj.org/article/863d6552694c41f8a3429b96706fcd46
Autor:
Emily K. Acton, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Todd A. Miano, Sascha Dublin, John R. Horn, Sophie Chung, Douglas J. Wiebe, Allison W. Willis, Charles E. Leonard
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Growing evidence suggests that drug interactions may be responsible for much of the known association between opioid use and unintentional traumatic injury. While prior research has focused on pairwise drug interactions, the role of higher-order (i.e
Externí odkaz:
https://doaj.org/article/8903caadb0e649668316aac9393704b4
Autor:
John D. Horn, Michael J. Johnson, Zbigniew Starosolski, Avner Meoded, Dianna M. Milewicz, Ananth Annapragada, Shaolie S. Hossain
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Moyamoya disease (MMD) is a progressive steno-occlusive cerebrovascular disease leading to recurrent stroke. There is a lack of reliable biomarkers to identify unilateral stroke MMD patients who are likely to progress to bilateral disease and experie
Externí odkaz:
https://doaj.org/article/c898209b6867446389e42ceb87778dca
Autor:
Charles E. Leonard, Colleen M. Brensinger, Thanh Phuong Pham Nguyen, John R. Horn, Sophie Chung, Warren B. Bilker, Sascha Dublin, Samantha E. Soprano, Ghadeer K. Dawwas, David W. Oslin, Douglas J. Wiebe, Sean Hennessy
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 130, Iss , Pp 110531- (2020)
Background: Efforts to minimize harms from opioid drug interactions may be hampered by limited evidence on which drugs, when taken concomitantly with opioids, result in adverse clinical outcomes. Objective: To identify signals of opioid drug interact
Externí odkaz:
https://doaj.org/article/fd6a7a9c408e4979b787885473c933fd
Autor:
Deepti Ramadoss, John P. Horn
In July 2021, sixteen months into the Covid-19 pandemic, the institutional climate for PhD training in the School of Medicine was assessed for a second time. This survey of graduate students occurred 1 year after initial surveys of graduate students
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::385b2e36dc3d49b966c6b324467f16c3
https://doi.org/10.1101/2022.01.13.476194
https://doi.org/10.1101/2022.01.13.476194
In July 2020, four months into the disruption of normal life caused by the Covid-19 pandemic, we assessed the institutional climate within the School of Medicine. Voluntary surveys were completed by 135 graduate students in 11 PhD-granting programs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::debb6f180282017d553751e30cea1d01
https://doi.org/10.1101/2022.01.06.475246
https://doi.org/10.1101/2022.01.06.475246