Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John P. Hinds"'
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272771 (2022)
MYC is one of the most dysregulated oncogenes and is thought to be fundamental to tumor formation and/or maintenance in many cancer types. This dominant pro-tumor activity makes MYC an attractive target for cancer therapy. However, MYC is a transcrip
Externí odkaz:
https://doaj.org/article/ca75accf74d641108228b7a91f836076
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225784 (2019)
Our primary goal is to therapeutically target the oncogenic transcription factor MYC to stop tumor growth and cancer progression. Here, we report aspects of the biophysical states of the MYC protein and its interaction with one of the best-characteri
Externí odkaz:
https://doaj.org/article/26a7772084ca417296973f55f6a1d8aa
Autor:
Jenny A Rudnick, Lisa M Arendt, Ina Klebba, John W Hinds, Vandana Iyer, Piyush B Gupta, Stephen P Naber, Charlotte Kuperwasser
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24605 (2011)
Fibroblasts are important in orchestrating various functions necessary for maintaining normal tissue homeostasis as well as promoting malignant tumor growth. Significant evidence indicates that fibroblasts are functionally heterogeneous with respect
Externí odkaz:
https://doaj.org/article/8c770b64fc1f420da2cf9d1615a89c98
Publikováno v:
Gastroenterology. 100:465-470
We measured anorectal sensory and motor function in 11 patients with multiple sclerosis and fecal incontinence, 11 continent patients with multiple sclerosis, 10 diabetics with fecal incontinence, and 12 healthy control subjects. The threshold volume
Publikováno v:
Gastroenterology. 98:1538-1542
An unselected outpatient population of 280 individuals with multiple sclerosis was surveyed to determine the prevalence of bowel dysfunction and to define their characteristics and their relationship to the nongastrointestinal manifestations of the d
Publikováno v:
Digestive diseases and sciences. 35(4)
We prospectively evaluated 36 patients who complained of chronic constipation and/or defecatory difficulties to determine the role of anorectal manometry and evacuation proctography in delineating the pathogenesis of these complaints. Twenty patients
Publikováno v:
Gastroenterology. 98:1394-1395
Publikováno v:
Gastroenterology. 97(4)
This study prospectively evaluated psychological profiles and selected parameters of colonic and anorectal sensorimotor function in 25 consecutive patients who were referred for severe idiopathic constipation. Measurement of colonic transit of radiop