Zobrazeno 1 - 10
of 50
pro vyhledávání: '"John P. Gray"'
Autor:
Spencer D. Fallek, Vikram S. Sandhu, Ryan A. McGill, John M. Gray, Holly N. Tinkey, Craig R. Clark, Kenton R. Brown
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract The trapped-ion quantum charge-coupled device (QCCD) architecture is a leading candidate for advanced quantum information processing. In current QCCD implementations, imperfect ion transport and anomalous heating can excite ion motion during
Externí odkaz:
https://doaj.org/article/53d0d882d9bb4b5a88bbe71815b6ea87
Autor:
Oluwarotimi O. Folorunso, Stephanie E. Brown, Jugajyoti Baruah, Theresa L. Harvey, Shekib A. Jami, Inna Radzishevsky, Herman Wolosker, James M. McNally, John A. Gray, Anju Vasudevan, Darrick T. Balu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The proper development and function of telencephalic GABAergic interneurons is critical for maintaining the excitation and inhibition (E/I) balance in cortical circuits. Glutamate contributes to cortical interneuron (CIN) development via N-m
Externí odkaz:
https://doaj.org/article/c1a3de421db14b62abea4c8f005bf011
Autor:
Inmaculada M. González-González, John A. Gray, Joana Ferreira, María Jose Conde-Dusman, Delphine Bouchet, Isabel Perez-Otaño, Laurent Groc
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112477- (2023)
Summary: Signaling via N-methyl-d-aspartate receptors (NMDARs) is critical for the maturation of glutamatergic synapses, partly through a developmental switch from immature synapses expressing primarily GluN2B- and GluN3A-containing subtypes to GluN2
Externí odkaz:
https://doaj.org/article/bf9666f4a96d4c7eb23dd56fc77bb8ac
Autor:
Mark A. Brimble, Pei-Hsin Cheng, Stephen M. Winston, Isaiah L. Reeves, Aisha Souquette, Yunyu Spence, Junfang Zhou, Yong-Dong Wang, Christopher L. Morton, Marcus Valentine, Paul G. Thomas, Amit C. Nathwani, John T. Gray, Andrew M. Davidoff
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 280-291 (2022)
Recombinant adeno-associated virus (rAAV) vectors are increasingly being used for clinical gene transfer and have shown great potential for the treatment of several monogenic disorders. However, contaminant DNA from producer plasmids can be packaged
Externí odkaz:
https://doaj.org/article/9ce90bd19a374a6086d2a19259d8a399
Autor:
Deborah K. Park, Samuel Petshow, Margarita Anisimova, Eden V. Barragan, John A. Gray, Ivar S. Stein, Karen Zito
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105772- (2022)
Schizophrenia is a psychiatric disorder that affects over 20 million people globally. Notably, schizophrenia is associated with decreased density of dendritic spines and decreased levels of d-serine, a co-agonist required for opening of the N-methyl-
Externí odkaz:
https://doaj.org/article/2f0119526f84455fa51830e1cb293a2b
Autor:
Joy Luba Lomole Waya, Richard Lako, Sudhir Bunga, Helen Chun, Valerie Mize, Boniface Ambani, Joseph Francis Wamala, Argata Guracha Guyo, John Henry Gray, Malick Gai, Sylvester Maleghemi, Matthew Kol
Publikováno v:
The Pan African Medical Journal, Vol 37, Iss 384 (2020)
INTRODUCTION: The coronavirus disease 2019 (COVID-19) was declared a pandemic on March 11, 2020. South Sudan, a low-income and humanitarian response setting, reported its first case of COVID-19 on April 5, 2020. We describe the socio-demographic and
Externí odkaz:
https://doaj.org/article/420e1554192940139f58d427b9387e9c
Publikováno v:
Case Reports in Vascular Medicine, Vol 2020 (2020)
Arterial dissection is a well-recognized pathology often seen in Vascular Surgery offices and Emergency Departments alike; however, visceral arterial dissection is an extremely rare, small subset of this entity. With that, an isolated celiac artery d
Externí odkaz:
https://doaj.org/article/c48e0193b5e54998bd030b21017f69d9
Autor:
Jenny A. Greig, Jayme M.L. Nordin, Christine Draper, Deirdre McMenamin, Edward A. Chroscinski, Peter Bell, John T. Gray, Laura K. Richman, James M. Wilson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 237-244 (2018)
Liver metabolism disorders are attractive targets for gene therapy, because low vector doses can reverse the buildup of toxic metabolites in the blood. Crigler-Najjar syndrome is an inherited disorder of bilirubin metabolism that is caused by the abs
Externí odkaz:
https://doaj.org/article/0cdfa4f8c1e84e47b68f369400bd39cb
Autor:
Calvin Ly, Alexandra C. Greb, Lindsay P. Cameron, Jonathan M. Wong, Eden V. Barragan, Paige C. Wilson, Kyle F. Burbach, Sina Soltanzadeh Zarandi, Alexander Sood, Michael R. Paddy, Whitney C. Duim, Megan Y. Dennis, A. Kimberley McAllister, Kassandra M. Ori-McKenney, John A. Gray, David E. Olson
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3170-3182 (2018)
Summary: Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the
Externí odkaz:
https://doaj.org/article/fab3a30f83314b318faa3be216735c44
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Neonicotinoids are known to affect insect navigation and vision, however the mechanisms of these effects are not fully understood. A visual motion sensitive neuron in the locust, the Descending Contralateral Movement Detector (DCMD), integra
Externí odkaz:
https://doaj.org/article/db266815db0d4fd0bfb1c2262cccac88