Zobrazeno 1 - 10
of 64
pro vyhledávání: '"John P. Driver"'
Autor:
Bianca L. Artiaga, Daniel Madden, Taeyong Kwon, Chester McDowell, Cassidy Keating, Velmurugan Balaraman, Darling Melany de Carvahlo Madrid, Laurie Touchard, Jamie Henningson, Philip Meade, Florian Krammer, Igor Morozov, Juergen A. Richt, John P. Driver
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1068 (2024)
Invariant natural killer T (iNKT) cells are glycolipid-reactive T cells with potent immunoregulatory properties. iNKT cells activated with the marine-sponge-derived glycolipid, α-galactosylceramide (αGC), provide a universal source of T-cell help t
Externí odkaz:
https://doaj.org/article/4868f73269404e89aa4a6ae8e8623447
Autor:
Bianca L. Artiaga, Igor Morozov, Russell Ransburgh, Taeyong Kwon, Velmurugan Balaraman, Sabarish V. Indran, Darling Melany De Carvalho Madrid, Weihong Gu, Jamie Henningson, Wenjun Ma, Jürgen A. Richt, John P. Driver
Publikováno v:
Animal Diseases, Vol 2, Iss 1, Pp 1-15 (2022)
Abstract Natural killer T (NKT) cells activated with the glycolipid ligand α-galactosylceramide (α-GalCer) stimulate a wide variety of immune cells that enhance vaccine-mediated immune responses. Several studies have used this approach to adjuvant
Externí odkaz:
https://doaj.org/article/ea1265ba55ee48449878b912d3357abe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response. A multitudinous group of lymphoid lineage cells does not fit the con
Externí odkaz:
https://doaj.org/article/8fabdf8613ed49518612798e8abc912b
Autor:
Darling Melany de C. Madrid, Weihong Gu, Bianca L. Artiaga, Guan Yang, Julia Loeb, Ian K. Hawkins, William L. Castleman, John A. Lednicky, Jürgen A. Richt, John P. Driver
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Influenza virus infections are a major cause of respiratory disease in humans. Neuraminidase inhibitors (NAIs) are the primary antiviral medication used to treat ongoing influenza infections. However, NAIs are not always effective for controlling vir
Externí odkaz:
https://doaj.org/article/1327e89a15c44f6abf55a6fe03ea04b8
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111050- (2022)
Summary: Many aspects of the porcine immune system remain poorly characterized, which poses a barrier to improving swine health and utilizing pigs as preclinical models. Here, we employ single-cell RNA sequencing (scRNA-seq) to create a cell atlas of
Externí odkaz:
https://doaj.org/article/91311324d54a4e28bb733be79417a068
Autor:
John P. Driver, Darling Melany de Carvalho Madrid, Weihong Gu, Bianca L. Artiaga, Jürgen A. Richt
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Influenza A viruses (IAVs) circulate widely among different mammalian and avian hosts and sometimes give rise to zoonotic infections. Vaccination is a mainstay of IAV prevention and control. However, the efficacy of IAV vaccines is often suboptimal b
Externí odkaz:
https://doaj.org/article/87061c3815094a9d8817ab85fd701543
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD1d-restricted invariant natural killer T (iNKT) cells are innate-like T cells that express an invariant T cell receptor (TCR) α-chain and recognize self and foreign glycolipid antigens. They can rapidly respond to agonist activation and stimulate
Externí odkaz:
https://doaj.org/article/6158b59e9070407bb4bfb09e794fc3a1
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
For more than 35 years, the NOD mouse has been the primary animal model for studying autoimmune diabetes. During this time, striking similarities to the human disease have been uncovered. In both species, unusual polymorphisms in a major histocompati
Externí odkaz:
https://doaj.org/article/653f97150f07450da6c8106f2a47115d
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 68 (2017)
Invariant natural killer T (iNKT) cells are an “innate-like” T cell lineage that recognize glycolipid rather than peptide antigens by their semi-invariant T cell receptors. Because iNKT cells can stimulate an extensive array of immune responses,
Externí odkaz:
https://doaj.org/article/21fab40a0508448a97399b631371e2b7
Autor:
Tania S. Bonny, John P. Driver, Taylor Paisie, Marco Salemi, John Glenn Morris, Lisa A. Shender, Lisa Smith, Carolyn Enloe, Kevin Oxenrider, Jeffery A. Gore, Julia C. Loeb, Chang-Yu Wu, John A. Lednicky
Publikováno v:
Diseases, Vol 5, Iss 1, p 7 (2017)
Bats are natural reservoirs of coronaviruses and other viruses with zoonotic potential. Florida has indigenous non-migratory populations of Brazilian free-tailed bats (Tadarida brasiliensis) that mostly roost in colonies in artificial structures. Unl
Externí odkaz:
https://doaj.org/article/d073be62ab2a4236a82268657680b03c