Zobrazeno 1 - 10
of 181
pro vyhledávání: '"John P Mordes"'
Autor:
Agata Jurczyk, Steven C Pino, Bryan O'Sullivan-Murphy, Martha Addorio, Erich A Lidstone, Philip Diiorio, Kathryn L Lipson, Clive Standley, Kevin Fogarty, Lawrence Lifshitz, Fumihiko Urano, John P Mordes, Dale L Greiner, Aldo A Rossini, Rita Bortell
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11812 (2010)
The centrosome is important for microtubule organization and cell cycle progression in animal cells. Recently, mutations in the centrosomal protein, pericentrin, have been linked to human microcephalic osteodysplastic primordial dwarfism (MOPD II), a
Externí odkaz:
https://doaj.org/article/87eb60336d2e4579be48ca104bae968e
Autor:
Steven C Pino, Bryan O'Sullivan-Murphy, Erich A Lidstone, Chaoxing Yang, Kathryn L Lipson, Agata Jurczyk, Philip diIorio, Michael A Brehm, John P Mordes, Dale L Greiner, Aldo A Rossini, Rita Bortell
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5468 (2009)
Gimap5 (GTPase of the immunity-associated protein 5) has been linked to the regulation of T cell survival, and polymorphisms in the human GIMAP5 gene associate with autoimmune disorders. The BioBreeding diabetes-prone (BBDP) rat has a mutation in the
Externí odkaz:
https://doaj.org/article/b47c27fdea4649c3bca3dcc7d7cff892
Autor:
Marika Bogdani, Linda Faxius, Malin Fex, Anita Ramelius, Anya Wernersson, John P. Mordes, Elizabeth P. Blankenhorn, Åke Lernmark
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The depleting Vβ13a T cell receptor monoclonal antibody (mAb) 17D5 prevents both induced and spontaneous autoimmune diabetes in BB rats. Here it was tested in congenic DRLyp/Lyp rats, all of which spontaneously developed diabetes. Starting at 40 day
Externí odkaz:
https://doaj.org/article/e1a7e8195e1e4c168a52d1dc2471ea9b
Autor:
Laura Cort, Brian G. Pierce, John P. Mordes, Ryan A. Eberwine, Elizabeth P. Blankenhorn, Zhijun Liu
Publikováno v:
Genes
Volume 12
Issue 6
Genes, Vol 12, Iss 852, p 852 (2021)
Volume 12
Issue 6
Genes, Vol 12, Iss 852, p 852 (2021)
Genetic analyses of human type 1 diabetes (T1D) have yet to reveal a complete pathophysiologic mechanism. Inbred rats with a high-risk class II major histocompatibility complex (MHC) haplotype (RT1B/Du) can illuminate such mechanisms. Using T1D-susce
Autor:
Qingqing Lou, Jitao Feng, Lin Liu, Yong Huang, Yanjun Liu, Zhaohui Fang, Jianping Shen, John P. Mordes, Tao Chen, Xiaodan Yuan, Jianing Li, Xia Dai, Cunyi Hsue, Chao Liu, Joshua D. Miller
Publikováno v:
Journal of Diabetes. 12:25-37
It is clear that aerobic training (AT) can delay pancreatic exhaustion and slow the progression from prediabetes to type 2 diabetes (T2D), but there is little information regarding the effects of resistance training (RT) in people with prediabetes. T
Autor:
Malin Fex, Marika Bogdani, Anya Wernersson, Anita Ramelius, Elizabeth P. Blankenhorn, Linda Faxius, Åke Lernmark, John P. Mordes
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
The depleting Vβ13a T cell receptor monoclonal antibody (mAb) 17D5 prevents both induced and spontaneous autoimmune diabetes in BB rats. Here it was tested in congenic DRLyp/Lyp rats, all of which spontaneously developed diabetes. Starting at 40 day
Publikováno v:
Immunotherapy of Diabetes and Selected Autoimmune Diseases ISBN: 9781351073448
Immunotherapy of Diabetes and Selected Autoimmune Diseases
Immunotherapy of Diabetes and Selected Autoimmune Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8d3055beafcbed4a2d7137d32845409
https://doi.org/10.1201/9781351073448-3
https://doi.org/10.1201/9781351073448-3
Autor:
Frank Bearoff, Patrick W Marsh, Elizabeth P. Blankenhorn, Åke Lernmark, Ozkan Aydemir, Janelle A. Noble, Jeffrey A. Bailey, John P. Mordes, Agnes Andersson Svärd
Publikováno v:
Diabetes
Type 1 diabetes (T1D) involves the interaction of multiple gene variants, environmental factors, and immunoregulatory dysfunction. Major T1D genetic risk loci encode HLA-DR and -DQ. Genetic heterogeneity and linkage disequilibrium in the highly polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c58011882c7a3bda6a882a15599e6bb
https://europepmc.org/articles/PMC6609989/
https://europepmc.org/articles/PMC6609989/
Autor:
Chaoxing Yang, Rita Bortell, Sarah R. Oikemus, John P. Mordes, Michael H. Brodsky, Suvana Lin, Glennice Ryan, Natasha Qaisar, Jennifer P. Wang
Publikováno v:
Diabetes
The pathogenesis of human type 1 diabetes, characterized by immune-mediated damage of insulin-producing β-cells of pancreatic islets, may involve viral infection. Essential components of the innate immune antiviral response, including type I interfe
Autor:
Fang Zhao, Xia Dai, Xiaohui Guo, Li Yuan, Huiying Yang, Qingqing Lou, Jin Huang, Zilin Sun, John P. Mordes, Lin Liu, Li Shen
Publikováno v:
Diabetes/Metabolism Research and Reviews. 31:811-816
BACKGROUND The prevalence of type 2 diabetes in China is increasing rapidly. Appropriate management of glycemia, blood pressure and dyslipidemia in this population is a major public health concern. OBJECTIVE The aim of this study was to assess metabo