Zobrazeno 1 - 10
of 68
pro vyhledávání: '"John P Christianson"'
Autor:
Anthony Djerdjaj, Nathaniel S Rieger, Bridget H Brady, Bridget N Carey, Alexandra J Ng, John P Christianson
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0281794 (2023)
The ability to detect, appraise, and respond to another's emotional state is essential to social affective behavior. This is mediated by a network of brain regions responsible for integrating external cues with internal states to orchestrate situatio
Externí odkaz:
https://doaj.org/article/4fb2a5b51c2d434e8780ca2a00d7fc7b
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0200971 (2018)
Familiarity between conspecifics may influence how social affective cues shape social behaviors. In a social affective preference test, experimental rats, when given the choice to explore an unfamiliar stressed or a naive adult, will avoid interactio
Externí odkaz:
https://doaj.org/article/4a482e8638da4fae9800d00dd8725a58
Autor:
Simon R. Bushell, Ashley C. W. Pike, Maria E. Falzone, Nils J. G. Rorsman, Chau M. Ta, Robin A. Corey, Thomas D. Newport, John C. Christianson, Lara F. Scofano, Chitra A. Shintre, Annamaria Tessitore, Amy Chu, Qinrui Wang, Leela Shrestha, Shubhashish M. M. Mukhopadhyay, James D. Love, Nicola A. Burgess-Brown, Rebecca Sitsapesan, Phillip J. Stansfeld, Juha T. Huiskonen, Paolo Tammaro, Alessio Accardi, Elisabeth P. Carpenter
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
TMEM16K is a member of the TMEM16 family of integral membrane proteins that are either lipid scramblases or chloride channels. Here the authors combine cell biology, electrophysiology measurements, X-ray crystallography, cryo-EM and MD simulations to
Externí odkaz:
https://doaj.org/article/602dd2cc133c49529d8807b7b0d875ca
Autor:
Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson
Publikováno v:
eLife, Vol 9 (2020)
Ubiquitin ligases (E3s) embedded in the endoplasmic reticulum (ER) membrane regulate essential cellular activities including protein quality control, calcium flux, and sterol homeostasis. At least 25 different, transmembrane domain (TMD)-containing E
Externí odkaz:
https://doaj.org/article/1e66b996a9fb4681a2ea07de56be7231
Autor:
John P. Christianson
Publikováno v:
American Journal of Psychiatry. 180:262-264
Autor:
Milena Vitale, Anush Bakunts, Andrea Orsi, Federica Lari, Laura Tadè, Alberto Danieli, Claudia Rato, Caterina Valetti, Roberto Sitia, Andrea Raimondi, John C Christianson, Eelco van Anken
Publikováno v:
eLife, Vol 8 (2019)
How endoplasmic reticulum (ER) stress leads to cytotoxicity is ill-defined. Previously we showed that HeLa cells readjust homeostasis upon proteostatically driven ER stress, triggered by inducible bulk expression of secretory immunoglobulin M heavy c
Externí odkaz:
https://doaj.org/article/1fadbf5d07454278a95cd18f5e2395cb
Serotonin modulates social responses to stressed conspecifics via insular 5-HT (2C) receptors in rat
Publikováno v:
bioRxiv
Social interaction allows for the transfer of affective states among individuals, and the behaviors and expressions associated with pain and fear can evoke anxiety-like states in observers which shape subsequent social interactions. We hypothesized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3edefac8788a12794ec014a37093a8
https://europepmc.org/articles/PMC9949146/
https://europepmc.org/articles/PMC9949146/
Autor:
Nathaniel S. Rieger, Juan A. Varela, Alexandra J. Ng, Lauren Granata, Anthony Djerdjaj, Heather C. Brenhouse, John P. Christianson
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47(6)
Impairments in identifying and responding to the emotions of others manifest in a variety of psychopathologies. Therefore, elaborating the neurobiological mechanisms that underpin social responses to social emotions, or social affective behavior, is
Publikováno v:
Behavioural Brain Research. 435:114050
Vocalizations, chemosignals, and behaviors are influenced by one's internal affective state and are used by others to shape social behaviors. A network of interconnected brain structures, often called the social behavior network or social decision-ma
Autor:
Anthony Djerdjaj, Morgan M. Rogers-Carter, Katherine B. Gribbons, Juan A. Varela, John P. Christianson
Publikováno v:
J Neurosci
Social interactions are shaped by features of the interactants, including age, emotion, sex, and familiarity. Age-specific responses to social affect are evident when an adult male rat is presented with a pair of unfamiliar male conspecifics, one of