Zobrazeno 1 - 10
of 489
pro vyhledávání: '"John P Atkinson"'
Autor:
Maria I Fonseca, Shuhui Chu, Aimee L Pierce, William D Brubaker, Richard E Hauhart, Diego Mastroeni, Elizabeth V Clarke, Joseph Rogers, John P Atkinson, Andrea J Tenner
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149792 (2016)
Chronic activation of the complement system and induced inflammation are associated with neuropathology in Alzheimer's disease (AD). Recent large genome wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in the C3b
Externí odkaz:
https://doaj.org/article/e80b68870340438f96ecae3c7cc77d03
Autor:
Amelia K Pinto, Hilario J Ramos, Xiaobo Wu, Shilpa Aggarwal, Bimmi Shrestha, Matthew Gorman, Kristin Y Kim, Mehul S Suthar, John P Atkinson, Michael Gale, Michael S Diamond
Publikováno v:
PLoS Pathogens, Vol 10, Iss 4, p e1004086 (2014)
The type I interferon (IFN) signaling response limits infection of many RNA and DNA viruses. To define key cell types that require type I IFN signaling to orchestrate immunity against West Nile virus (WNV), we infected mice with conditional deletions
Externí odkaz:
https://doaj.org/article/c8d49265e18846b997d2aafa046d8842
Autor:
Patience B Tetteh-Quarcoo, Christoph Q Schmidt, Wai-Hong Tham, Richard Hauhart, Haydyn D T Mertens, Arthur Rowe, John P Atkinson, Alan F Cowman, J Alexandra Rowe, Paul N Barlow
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34820 (2012)
Complement receptor-type 1 (CR1, CD35) is the immune-adherence receptor, a complement regulator, and an erythroid receptor for Plasmodium falciparum during merozoite invasion and subsequent rosette formation involving parasitized and non-infected ery
Externí odkaz:
https://doaj.org/article/1bd17d28c12044c59c9376624a417214
Autor:
Jane E Salmon, Cara Heuser, Michael Triebwasser, M Kathryn Liszewski, David Kavanagh, Lubka Roumenina, D Ware Branch, Tim Goodship, Veronique Fremeaux-Bacchi, John P Atkinson
Publikováno v:
PLoS Medicine, Vol 8, Iss 3, p e1001013 (2011)
Pregnancy in women with systemic lupus erythematosus (SLE) or antiphospholipid antibodies (APL Ab)--autoimmune conditions characterized by complement-mediated injury--is associated with increased risk of preeclampsia and miscarriage. Our previous stu
Externí odkaz:
https://doaj.org/article/1b26febdcd804b58aaa8bfc8862bf688
Publikováno v:
PLoS Pathogens, Vol 4, Iss 12, p e1000249 (2008)
Poxviruses subvert the host immune response by producing immunomodulatory proteins, including a complement regulatory protein. Ectromelia virus provides a mouse model for smallpox where the virus and the host's immune response have co-evolved. Using
Externí odkaz:
https://doaj.org/article/2503160090c6487e97ac92a673524df2
Autor:
Panisadee Avirutnan, Lijuan Zhang, Nuntaya Punyadee, Ananya Manuyakorn, Chunya Puttikhunt, Watchara Kasinrerk, Prida Malasit, John P Atkinson, Michael S Diamond
Publikováno v:
PLoS Pathogens, Vol 3, Iss 11, p e183 (2007)
Dengue virus (DENV) nonstructural protein-1 (NS1) is a secreted glycoprotein that is absent from viral particles but accumulates in the supernatant and on the plasma membrane of cells during infection. Immune recognition of cell surface NS1 on endoth
Externí odkaz:
https://doaj.org/article/29a6b69726c64cd7b7fcbb6be0d9e168
Autor:
Johanna M. Seddon, Dikha De, William Casazza, Shun-Yun Cheng, Claudio Punzo, Mark Daly, Danlei Zhou, Samantha L. Coss, John P. Atkinson, Chack-Yung Yu
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Introduction: Age-related macular degeneration (AMD) is the leading cause of central vision loss in the elderly. One-third of the genetic contribution to this disease remains unexplained.Methods: We analyzed targeted sequencing data from two independ
Externí odkaz:
https://doaj.org/article/b3376f1811e74e0083f92b034e76bf47
Autor:
Ajay A. Madhavan, MD, John C. Benson, MD, Jeremy K. Cutsforth-Gregory, MD, John D. Atkinson, MD, Carrie M. Carr, MD
Publikováno v:
Radiology Case Reports, Vol 17, Iss 9, Pp 2968-2971 (2022)
Spontaneous intracranial hypotension can be caused by spinal dural tears or CSF-venous fistulas. It is rare for patients to have more than one type of leak at any given time. Here, we illustrate 3 examples of dural tears that co-existed with CSF-veno
Externí odkaz:
https://doaj.org/article/6935eca83b7f4aaebd73f347d223f001
Autor:
Pooja Khonde, Deyali Chatterjee, Madonna Bogacki, M. Kathryn Liszewski, Andria L. Ford, Jonathan J. Miner, John P. Atkinson, Elizabeth M. Brunt
Publikováno v:
Human Pathology. 135:22-34
Autor:
Sanjaya K. Sahu, Ayşe N. Ozantürk, Devesha H. Kulkarni, Lina Ma, Ruteja A. Barve, Linus Dannull, Angel Lu, Marick Starick, Ja’Nia McPhatter, Lorena Garnica, Maxwell Sanfillipo-Burchman, Jeremy Kunen, Xiaobo Wu, Andrew E. Gelman, Steven L. Brody, John P. Atkinson, Hrishikesh S. Kulkarni
Publikováno v:
Science Immunology. 8
The complement component C3 is a fundamental plasma protein for host defense, produced largely by the liver. However, recent work has demonstrated the critical importance of tissue-specific C3 expression in cell survival. Here, we analyzed the effect