Derivation, validation, and comparison of a new prognostic scoring system for acute lower gastrointestinal bleeding

Autor: Christopher Smith, Gillian Leggett, Anthoor Jayaprakash, Mohammed Khan, John M. Thomson, Balasubramaniam Vijayan, Andrew Fraser, John S. Leeds

Publikováno v: DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)

Abstract Objectives Lower gastrointestinal bleeding is a common presentation with little data concerning risk factors for adverse outcomes. The aim was to derive and validate a scoring system to stratify risk in lower gastrointestinal bleeding and co

Externí odkaz: https://doaj.org/article/9dba2a25f4dc491dbb1931590b5dcfa4

Genome-Wide Methylation Profiling in 229 Patients With Crohn’s Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn’s Disease (TOPPIC)Summary

Autor: Nicholas T. Ventham, Nicholas A. Kennedy, Rahul Kalla, Alex T. Adams, Alexandra Noble, Holly Ennis, Craig Mowat, Malcolm G. Dunlop, Jack Satsangi, Ian Arnott, Aiden Cahill, Malcolm Smith, Tariq Ahmad, Sreedhar Subramanian, Simon Travis, John Morris, John Hamlin, Anjan Dhar, Chuka Nwokolo, Cathryn Edwards, Tom Creed, Stuart Bloom, Mohamed Yousif, Linzi Thomas, Simon Campbell, Stephen J. Lewis, Shaji Sebastian, Sandip Sen, Simon Lal, Chris Hawkey, Charles Murray, Fraser Cummings, Jason Goh, James O. Lindsay, Naila Arebi, Lindsay Potts, Aileen J. McKinley, John M. Thomson, John A. Todd, Mhairi Collie, Ashley Mowat, Daniel R. Gaya, Jack Winter, Graham D. Naismith, Catriona Keerie, Steff Lewis, Robin J. Prescott, Gordan Lauc, Harry Campbell, Dermot P.B. McGovern, Vito Annese, Vlatka Zoldoš, Iain K. Permberton, Manfred Wuhrer, Daniel Kolarich, Daryl L. Fernandes, Evropi Theorodorou, Victoria Merrick Daniel I. Spencer, Richard A. Gardner, Ray Doran, Archana Shubhakar, Ray Boyapati, Igor Rudan, Paolo Lionetti, Irena Trbojević Akmačić, Jasminka Krištić, Frano Vuč ković, Jerko Štambuk, Mislav Novokmet, Maja Pučić-Baković, Olga Gornik, Angelo Andriulli, Laura Cantoro, Giancarlo Sturniolo, Gionata Fiorino, Natalia Manetti, Anna Latiano, Anna Kohn, Renata D’Inca`, Silvio Danese, Ian D. Arnott, Colin L. Noble, Charlie W. Lees, Alan G. Shand, Gwo-Tzer Ho, Lee Murphy, Jude Gibson, Louise Evenden, Nicola Wrobel, Tamara Gilchrist, Angie Fawkes, Guinevere S.M. Kammeijer, Florent Clerc, Noortje de Haan, Aleksandar Vojta, Ivana Samaržija, Dora Markulin, Marija Klasić, Paula Dobrinić, Yurii Aulchenko, Tim van den Heuve, Daisy Jonkers, Marieke Pierik

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 431-450 (2023)

Background & Aims: DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine whether the circulating DNA me

Externí odkaz: https://doaj.org/article/f32b67ecfa854c6487a3c5196a5070e3

Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

Autor: Robert L. Hollis, John P. Thomson, Barbara Stanley, Michael Churchman, Alison M. Meynert, Tzyvia Rye, Clare Bartos, Yasushi Iida, Ian Croy, Melanie Mackean, Fiona Nussey, Aikou Okamoto, Colin A. Semple, Charlie Gourley, C. Simon Herrington

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)

The molecular classification of endometroid ovarian carcinomas (EnOC) has not been established, preventing the development of stratified therapeutic approaches. Here the authors characterise the molecular landscape of EnOC by whole exome sequencing,

Externí odkaz: https://doaj.org/article/232b42338ac04ca39f011da44d0890a8

Prediction Method of Driving Strategy of High-Power IGBT Module Based on MEA-BP Neural Network

Autor: Zhaoliang Meng, Yuan Yang, Yong Gao, Shengsheng Ai, Yue Zhang, Yaru Lv, Zetao Zhang, Yang Wen, Lei Wu, Ping Zhang, John Douglas Thomson

Publikováno v: IEEE Access, Vol 8, Pp 94731-94747 (2020)

An insulated gate bipolar transistor (IGBT) driver is crucial for improving the reliability of a power electronics system. This paper proposes a method for predicting the optimal driving strategy of high-power IGBT module based on backpropagation neu

Externí odkaz: https://doaj.org/article/2ec12be9d01c45739debf71cc546e4f4

The Scottish COVID Cancer Immunity Prevalence Study: A Longitudinal Study of SARS-CoV-2 Immune Response in Patients Receiving Anti–Cancer Treatment

Autor: Karin Purshouse, John P Thomson, Mahéva Vallet, Lorna Alexander, Isaac Bonisteel, Maree Brennan, David A Cameron, Jonine D Figueroa, Elizabeth Furrie, Pamela Haig, Mattea Heck, Hugh McCaughan, Paul Mitchell, Heather McVicars, Lorraine Primrose, Ines Silva, Kate Templeton, Natalie Wilson, Peter S Hall

Publikováno v: Purshouse, K, Thomson, J P, Vallet, M, Alexander, L, Bonisteel, I, Brennan, M, Cameron, D A, Figueroa, J D, Furrie, E, Haig, P, Heck, M, Mccaughan, H, Mitchell, P, Mcvicars, H, Primrose, L, Silva, I, Templeton, K, Wilson, N & Hall, P S 2023, ' The Scottish COVID Cancer Immunity Prevalence Study: A Longitudinal Study of SARS-CoV-2 Immune Response in Patients Receiving Anti–Cancer Treatment ', The Oncologist . https://doi.org/10.1093/oncolo/oyac257, https://doi.org/10.1093/oncolo/oyac257

Background Cancer and anti-cancer treatment (ACT) may be risk factors for severe SARS-CoV-2 infection and limited vaccine efficacy. Long–term longitudinal studies are needed to evaluate these risks. The Scottish COVID cancer immunity prevalence (SC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b049fed637355b9b0d849624398af19
https://doi.org/10.1093/oncolo/oyac257