Výsledky vyhledávání - "John P, Chamberland"

Supplementary Data 5 from Direct Role of Adiponectin and Adiponectin Receptors in Endometrial Cancer: In Vitro and Ex Vivo Studies in Humans

Autor: Christos S. Mantzoros, Sofia Tseleni-Balafouta, Konstantinos Aronis, John P. Chamberland, Hyun-Seuk Moon

PDF file - 74K, The cell culture and introduction of AdipRs siRNA were performed as described in detail in the "Methods" section. The cells were treated with adiponectin (20 �g/ml) for 24 hr (A) and for 30 min (B). The proliferation assay and Weste

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https://doi.org/10.1158/1535-7163.22496829

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Supplementary Data 3 from Direct Role of Adiponectin and Adiponectin Receptors in Endometrial Cancer: In Vitro and Ex Vivo Studies in Humans

Autor: Christos S. Mantzoros, Sofia Tseleni-Balafouta, Konstantinos Aronis, John P. Chamberland, Hyun-Seuk Moon

PDF file - 134K, Immunohistochemical analysis was performed as described in detail in the "Materials and Methods" section. A&F: normal human proliferative endometrial tissue, B&G: human decidual, C&H: human hyperplastic endometrium, D&I: normal human

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https://doi.org/10.1158/1535-7163.22496835

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Data from Abdominal Obesity, Independent from Caloric Intake, Accounts for the Development of Intestinal Tumors in Apc1638N/+ Female Mice

Autor: Christos S. Mantzoros, John P. Chamberland, Gil Atzmon, John J. Lofrese, Xueying Zhang, Leonard H. Augenlicht, Derek M. Huffman

To determine whether visceral fat (VF), independent of other confounders, is causally linked to intestinal tumorigenesis, we surgically removed visceral fat in Apc1638/N+ mice. At 15 weeks of age, male and female Apc1638/N+ mice were randomized to on

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https://doi.org/10.1158/1940-6207.c.6544508

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Supplementary Data 4 from Direct Role of Adiponectin and Adiponectin Receptors in Endometrial Cancer: In Vitro and Ex Vivo Studies in Humans

Autor: Christos S. Mantzoros, Sofia Tseleni-Balafouta, Konstantinos Aronis, John P. Chamberland, Hyun-Seuk Moon

PDF file - 67K, The cells were cultured as described in detail in the "Materials and Methods" section. Expression of adiponectin receptors in KLE and RL95-2 cell lines was detected by Western Blotting. Human subcutaneous adipose tissue (SCF) was used

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https://doi.org/10.1158/1535-7163.22496832

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Retromer revisited: Evolving roles for retromer in endosomal sorting

Autor: John P. Chamberland, Brigitte Ritter

Publikováno v: The Journal of Cell Biology

By revisiting the classical role of retromer in endosomal sorting of the cation-independent mannose 6-phosphate receptor (CI-MPR), Simonetti et al. reveal that CI-MPR sorting actually occurs via SNX1/2–SNX5/6 membrane-tubulating complexes, thereby

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https://doi.org/10.1083/jcb.201708111

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Fetuin-A levels and free leptin index are reduced in patients with chronic lymphocytic leukemia: a hospital-based case-control study

Autor: Ilias Migdalis, Antigoni Lekka, Maria Dalamaga, Stergios A. Polyzos, Maria Triantafilli, John P. Chamberland, Christos S. Mantzoros, Evangelia Papadavid, Konstantinos Karmaniolas

Publikováno v: Leukemia & Lymphoma. 57:577-584

There are limited data on fetuin-A, soluble leptin receptor (sOB-R) and free leptin index (FLI) in patients with chronic lymphocytic leukemia (CLL). The aim of this study was to compare circulating fetuin-A, sOB-R levels and FLI between 95 patients w

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https://doi.org/10.3109/10428194.2015.1075523

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Lack of mature lymphocytes results in obese but metabolically healthy mice when fed a high-fat diet

Autor: Huizhi Gong, Xiaowen Liu, Joo Young Huh, O-P R Hamnvik, Christos S. Mantzoros, John P. Chamberland, Mary Brinkoetter

Publikováno v: International Journal of Obesity. 39:1548-1557

Obesity is characterized by chronic inflammation and immune dysregulation, as well as insulin resistance, but the link between obesity and adaptive immunity remains to be fully studied. To elucidate the role of adaptive immunity on body composition,

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https://doi.org/10.1038/ijo.2015.93

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Omentin-1 levels are reduced by pharmacologic doses of leptin, but remain unaffected by energy deprivation and display no day–night variation

Autor: Christos S. Mantzoros, Konstantinos N. Aronis, Ole-Petter R. Hamnvik, Benjamin E. Schneider, Bindiya Thakkar, John P. Chamberland

Publikováno v: International journal of obesity (2005)

Objective To study the day-night variation of omentin-1 levels and assess whether leptin, and/or short-and long-term energy deprivation alter circulating omentin-1 levels via cytokines. Design and Methods Omentin-1 levels were measured hourly in seru

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https://doi.org/10.1038/ijo.2014.106

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