Zobrazeno 1 - 10
of 19
pro vyhledávání: '"John Orgah"'
Autor:
Yule Wang, Shuang He, Xinyan Liu, Zhixiong Li, Lin Zhu, Guangxu Xiao, Xiaoli Du, Hongxia Du, Wen Zhang, Yiqian Zhang, John Orgah, Yuxin Feng, Boli Zhang, Yan Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Effective therapies for stroke are still limited due to its complex pathological manifestations. QiShenYiQi (QSYQ), a component-based Chinese medicine capable of reducing organ injury caused by ischemia/reperfusion, may offer an alternative option fo
Externí odkaz:
https://doaj.org/article/53106faef4474caca2cd006d9340f260
Autor:
Xiaohu Yang, John Orgah, Dandan Wang, Guanwei Fan, Hu Jingyang, Jihong Han, Gangjian Qin, Xiumei Gao, Yan Zhu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Although Danhong injection (DHI) is one of the most prescribed cardiovascular medicines in China, its therapeutic indications and mechanisms remain partially defined. We now identify molecular targets of DHI in resistance vasculatures and de
Externí odkaz:
https://doaj.org/article/710ceb661faa41bf82d55f05f5a93304
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78026 (2013)
BACKGROUND AND PURPOSE: Shenfu injection (SFI), derived from the ancient traditional Chinese medicine (Red Radix Ginseng and Radix Aconitum Carmichaeli), has been widely used in the clinical for the treatment of cardiovascular diseases for more than
Externí odkaz:
https://doaj.org/article/a1c31d282de44b6888aa6611813d0215
Publikováno v:
Neuropsychiatric Disease and Treatment
Vascular dementia (VaD), a cognitive disorder caused by cerebrovascular pathologies, is the most common cause of dementia in the elderly, being second only to Alzheimer’s disease. Researches have shown that adequate cerebral blood flow (CBF) is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132ba3b6cf9b6e40777da7b96430dc1d
http://europepmc.org/articles/PMC8502063
http://europepmc.org/articles/PMC8502063
Autor:
Shuang He, Haixin Liu, John Orgah, Jie Ren, Tiechan Zhao, Jiang Zhenzuo, Yuefei Wang, Peng Zhang, Xiumei Gao, Yan Zhu, Rongrong Chen, Zihao Chen, Li Peng
Objective: We aimed to investigate the chemical basis and mechanism of angiogenesis regulation by a multicomponent Chinese medicine Danhong injection (DHI). Methods: A chemical fraction library of DHI was screened and validated for angiogenesis activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cefaceac62ac3947e6ad69a1389e309
https://doi.org/10.21203/rs.3.rs-961602/v1
https://doi.org/10.21203/rs.3.rs-961602/v1
Publikováno v:
Restorative Neurology and Neuroscience. 37:375-395
Background A cerebral ischemic stroke involves mitochondrial dysfunction, motor deficits, and paralysis; and Danhong injection (DHI) might possess mitochondrial protection and functional recovery in a stroke subject through promoting expression of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fe8f2239d8bfbd1fe215a7d4b7755f
https://doi.org/10.3233/rnn-180828
https://doi.org/10.3233/rnn-180828
Publikováno v:
Journal of Ethnopharmacology. 293:115301
Ischemic stroke is one of the leading causes of mortality and long-term disability worldwide. Currently, approved therapies of intravenous thrombolysis and mechanical thrombectomy are limited only to selected patients with rescuable brain tissue. Chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24723e3042f4d58579a7e0e50b20f18c
https://doi.org/10.1016/j.jep.2022.115301
https://doi.org/10.1016/j.jep.2022.115301
Publikováno v:
Gerontology. 64:457-465
Background: Tetrahydroxystilbene glucoside (TSG) is a main bioactive component of Polygonum multiflorum, a traditional Chinese medicine known for certain anti-aging effects. Since TSG has been found to extend lifespan in the nematode Caenorhabditis e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afe2267a6ad3bb1f2ea93e0745f8bef
https://doi.org/10.1159/000487360
https://doi.org/10.1159/000487360
Autor:
Xiumei Gao, Xiaohu Yang, John Orgah, Miao Wang, Jihong Han, Guanwei Fan, Gangjian Qin, Yan Zhu, Qi Zhang, Zhilong Wang, Dandan Wang
Publikováno v:
Kidney & Blood Pressure Research, Vol 43, Iss 1, Pp 12-24 (2018)
Background/Aims: High blood pressure is a major risk factor for chronic kidney disease. Currently, single-target anti-hypertensive drugs are not designed for high blood pressure-related organ damages. Danhong injection (DHI), made from the aqueous ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe1b54de4e9b7bbcfa4a6ce517c5828
https://doi.org/10.1159/000486735
https://doi.org/10.1159/000486735
Autor:
Hong Lv, Tong Yin, Yan Zhu, Wang Xianrui, Yaqing Guo, Xiaoming Wang, Hong-Hua Wu, Fan Zhang, Guixiang Pan, John Orgah
Publikováno v:
Journal of Ethnopharmacology. 209:264-282
Ethnopharmacological relevance Plants of the genus Cimicifuga have long been used as an ethnomedicine in China, Europe, and North America for its high medicinal value and health benefits. Their dried rhizomes are widely used for treating wind-heat he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79eb69092869363e5d5f4aade304a74f
https://doi.org/10.1016/j.jep.2017.07.040
https://doi.org/10.1016/j.jep.2017.07.040