Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation

Autor: Johana Monteserin, João Perdigão, Andrew Kitchen, Kristian Alfsnes, Francois Balloux, Maxine Caws, Ingerid Ørjansen Kirkeleite, Sarah J. Dunstan, Jon Bohlin, Isabel Portugal, Fatima Fandinho, Tyler S. Brown, Mary B. O’Neill, Dick van Soolingen, Kathryn E. Holt, Vegard Eldholm, Caitlin S. Pepperell, Miguel Viveiros, Louis Grandjean, Nadia Debech, Beatriz López, Barun Mathema, Edward J. Feil, Marcia Aparecida da Silva, John O.-H. Pettersson, Philip Noel Suffys, Viviana Ritacco, Ola Brønstad Brynildsrud, Phan Vuong Khac Thai, Taane G. Clark

Publikováno v: Science Advances
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Repeated emergence, not international dissemination, is behind the rise of multidrug-resistant lineage 4 tuberculosis.
On the basis of population genomic and phylogeographic analyses of 1669 Mycobacterium tuberculosis lineage 4 (L4) genomes, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fba6fdd2ef8ae46581ba751bc746eb0
https://doi.org/10.1126/sciadv.aat5869