Dynamic Optimization and Non-linear Model Predictive Control to Achieve Targeted Particle Morphologies

Autor: Preet Joy, Omar Naeem, José M. Asua, Juraj Kosek, Alexander Mitsos, Alexei A. Lapkin, Wolfgang Gerlinger, Noushin Rajabalinia, Shaghayegh Hamzehlou, Adel Mhamdi, Peter Singstad, John O. Suberu, Fredrik Gjertsen, Tomas Chaloupka, Johannes M.M. Faust, Jose R. Leiza, Ekkehard Jahns, Svein Olav Hauger

Publikováno v: Chemie-Ingenieur-Technik 91(3), 323-335 (2019). doi:10.1002/cite.201800118 special issue: "Special Issue: Digitalisierung in Forschung und Entwicklung"
Addi. Archivo Digital para la Docencia y la Investigación
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Chemie-Ingenieur-Technik

Chemie - Ingenieur - Technik x, xx (2018). doi:10.1002/cite.201800118
Published by Wiley-VCH Verl., Weinheim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7d81160be4e9ef1638fe9a836bb244
https://publications.rwth-aachen.de/record/753595

Integrating medicinal plants extraction into a high-value biorefinery: An example of Artemisia annua L

Autor: Guy C. Barker, Andrew J. Clark, Eba Adou, John O. Suberu, Benhilda Mlambo, Alexei A. Lapkin, Alana E. C. Collis, Smain Chemat

Publikováno v: Comptes Rendus Chimie. 17:232-241

A principle of biorefining is extended to medicinal plants with the view of developing a more sustainable business model for biomass producers and extractors. This is demonstrated for Artemisia annua L. currently cultivated or harvested in the wild f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ca7fd8ba36adfe149b1715c8acc349b
https://doi.org/10.1016/j.crci.2013.10.023

Cellular engineering of Artemisia annua and Artemisia dubia with the rol ABC genes for enhanced production of potent anti-malarial drug artemisinin

Autor: John O. Suberu, Bushra Mirza, Bushra Hafeez Kiani

Publikováno v: Malaria Journal

Background Malaria is causing more than half of a million deaths and 214 million clinical cases annually. Despite tremendous efforts for the control of malaria, the global morbidity and mortality have not been significantly changed in the last 50 yea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfc59a4db00f08da4e2d030a665450d
http://europepmc.org/articles/PMC4855502

The effect of O-methylated flavonoids and other co-metabolites on the crystallization and purification of artemisinin

Autor: John O. Suberu, Kai Leonhard, Guy C. Barker, Alexei A. Lapkin, Peyman Yamin, Neil Sullivan, Smain Chemat, Lijiang Song

Publikováno v: Journal of biotechnology. 171

Methoxylated flavonoids casticin, artemetin and retusin were identified as putative causative factors for low crystallization yields of artemisinin from extracts. Comparative profiling of biomass grown in different countries found elevated levels (�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e162d5f73471b2ab38f05fae7e4ff1
https://pubmed.ncbi.nlm.nih.gov/24333126

Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract--possible synergistic and resistance mechanisms.

Autor: John O Suberu, Alexander P Gorka, Lauren Jacobs, Paul D Roepe, Neil Sullivan, Guy C Barker, Alexei A Lapkin

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e80790 (2013)

Artemisia annua hot water infusion (tea) has been used in in vitro experiments against P. falciparum malaria parasites to test potency relative to equivalent pure artemisinin. High performance liquid chromatography (HPLC) and mass spectrometric analy

Externí odkaz: https://doaj.org/article/840410d0d1e8431c913375c68cfe8712