Accurate template-based modeling in CASP12 using the IntFOLD4-TS, ModFOLD6, and ReFOLD methods

Autor: Bajuna R. Salehe, Ali H. A. Maghrabi, Daniel B. Roche, John O. Nealon, Ahmad N. Shuid, Robert Kempster, Liam J. McGuffin, Jennifer D. Atkins

Publikováno v: Proteins: Structure, Function, and Genetics
Proteins: Structure, Function, and Genetics, 2018, 86, pp.335-344. ⟨10.1002/prot.25360⟩
Proteins: Structure, Function, and Genetics, Wiley, 2018, 86, pp.335-344. ⟨10.1002/prot.25360⟩

International audience; Our aim in CASP12 was to improve our Template‐Based Modeling (TBM) methods through better model selection, accuracy self‐estimate (ASE) scores and refinement. To meet this aim, we developed two new automated methods, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b1124c092328803fe484a0b04c4c6
https://doi.org/10.1002/prot.25360

Predictive and Experimental Approaches for Elucidating Protein–Protein Interactions and Quaternary Structures

Autor: Liam J. McGuffin, John O. Nealon, Limcy Seby Philomina

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 12, p 2623 (2017)
International Journal of Molecular Sciences

The elucidation of protein–protein interactions is vital for determining the function and action of quaternary protein structures. Here, we discuss the difficulty and importance of establishing protein quaternary structure and review in vitro and i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab722d76437fd53602ddc7a300988a6
https://doi.org/10.3390/ijms18122623