Zobrazeno 1 - 10
of 25
pro vyhledávání: '"John O. Capobianco"'
Autor:
Robert C. Goldman, Seth W. Snyder, Tom Mcgonigal, Karl A. Walter, Uri S. Ladror, John O. Capobianco, Sarah A. Dorwin, Rohinton Edalji, David A. Egan, Thomas F. Holzman, Robert W. Johnson, Aparna V. Sarthy
Publikováno v:
Protein Science. 7:2595-2601
Elongation-factor-3 (EF-3) is an essential factor of the fungal protein synthesis machinery. In this communication the structure of EF-3 from Saccharomyces cerevisiae is characterized by differential scanning calorimetry (DSC), ultracentrifugation, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7c059e34682363bfa73fa29b741180
https://doi.org/10.1002/pro.5560071213
https://doi.org/10.1002/pro.5560071213
Autor:
Robert C. Goldman, Florence Doucet-Populaire, John O. Capobianco, Vincent Jarlier, Dorothy Zakula
Publikováno v:
Journal of Antimicrobial Chemotherapy. 41:179-187
Clarithromycin, the 6-O-methyl derivative of erythromycin, is approved for treatment of Mycobacterium avium infections and for prophylaxis in patients at risk. Since clarithromycin is more active against mycobacteria than the parent compound, erythro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6430e390a0fb4b3e7082f42cf4db1deb
https://doi.org/10.1093/jac/41.2.179
https://doi.org/10.1093/jac/41.2.179
Publikováno v:
Journal of Antimicrobial Chemotherapy. 39:261-264
We have identified four non-azole inhibitors of lanosterol 14a-demethylase in Candida albicans CCH442. The most potent compound, A-39806, had IC50 values for ergosterol inhibition of 0.9 microM (0.3 mg/L) and 1.9 microM (0.6 mg/L) in whole cell and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce544ca2d712e94ce3be486ff1f7d79d
https://doi.org/10.1093/jac/39.2.261
https://doi.org/10.1093/jac/39.2.261
Autor:
John O. Capobianco, Robert C. Goldman
Publikováno v:
International Journal of Antimicrobial Agents. 4:183-189
[(14)C]Erythromycin and [(14)C]azithromycin uptake rates were studied in Escherichia coli strains containing normal OmpC and OmpF porins (strain MRC 106) and altered OmpC porins due to small insertions (strains RAM121 and OC1555) or deletions (strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620775c9849c90e71412c0f6aea16495
https://doi.org/10.1016/0924-8579(94)90007-8
https://doi.org/10.1016/0924-8579(94)90007-8
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:1496-1500
Clarithromycin is a recently approved macrolide with improved pharmacokinetics, antibacterial activity, and efficacy in treating bacterial infections including those caused by Helicobacter pylori, an agent implicated in various forms of gastric disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f582b0c349d3b278a49e8e36aac1ef2
https://doi.org/10.1128/aac.38.7.1496
https://doi.org/10.1128/aac.38.7.1496
Publikováno v:
Analytical Biochemistry. 204:96-102
A fluorescent method for monitoring the activity of the secreted Candida carboxyl (aspartic) proteinase (EC 3.4.23.6) was developed using a fluorogenic substrate based on resonance energy transfer. The fluorescent assay was used to monitor proteinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6bd7e7b66b95e5e9fc82b2b61e6b2f
https://doi.org/10.1016/0003-2697(92)90145-w
https://doi.org/10.1016/0003-2697(92)90145-w
Publikováno v:
Journal of General Microbiology. 138:1527-1533
Lipopolysaccharide (LPS) synthesis was inhibited, new lipid A metabolites accumulated, and growth ceased, when the plant pathogen Agrobacterium tumefaciens and the fish pathogen Aeromonas salmonicida were treated with an antibacterial agent which spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4106fa00d2c00770cf97a71ce0969cf
https://doi.org/10.1099/00221287-138-7-1527
https://doi.org/10.1099/00221287-138-7-1527
Publikováno v:
Journal of Antimicrobial Chemotherapy. 30:781-790
6-Hydroxy-N-methyl-N-(2-[4-phenylphenyl] ethyl)-1,2,3,4-tetrahydro-1- napthalene methanamine (A60586), a new non-azole inhibitor of ergosterol biosynthesis in Candida albicans ATCC62376 has been identified. In whole cells A60586 produced a dose relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7720b6bb5948f93872423dcee3e472c
https://doi.org/10.1093/jac/30.6.781
https://doi.org/10.1093/jac/30.6.781
Autor:
Leping Li, John O. Capobianco, Larry L. Klein, Robert C. Goldman, Dorothy Zakula, David Frost, Paul A. Lartey
Publikováno v:
Antimicrobial agents and chemotherapy. 42(2)
A novel synthetic cyclopeptamine, A172013, rapidly accumulated by passive diffusion into Candida albicans CCH442. Drug influx could not be totally facilitated by the membrane-bound target, β-(1,3)-glucan synthase, since accumulation was unsaturable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b053ec46a6e1531bfd0ab51dbdf950
https://pubmed.ncbi.nlm.nih.gov/9527791
https://pubmed.ncbi.nlm.nih.gov/9527791
Autor:
Karl A. Walter, Aparna V. Sarthy, Robert C. Goldman, Tom Mcgonigal, John O. Capobianco, Thomas H. Holzman, David A. Egan
Publikováno v:
Analytical biochemistry. 254(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8fd2d05e10653c822cf118fd629c79
https://pubmed.ncbi.nlm.nih.gov/9417791
https://pubmed.ncbi.nlm.nih.gov/9417791