Zobrazeno 1 - 10
of 818
pro vyhledávání: '"John Nicholas"'
Autor:
Ali Vaeli Zadeh, MD, Alexander Justicz, MD, Juan Plate, MD, Michael Cortelli, MD, I-wen Wang, MD, PhD, John Nicholas Melvan, MD, PhD
Publikováno v:
JTCVS Open, Vol 18, Iss , Pp 145-155 (2024)
Objective: Human immunodeficiency virus infection (HIV+) is associated with a 2-fold increased risk of cardiovascular disease. Increasingly, patients who are HIV + are being evaluated to undergo cardiac surgery. Current risk-adjusted scoring systems,
Externí odkaz:
https://doaj.org/article/a065cf3923ab4e06bf0fb88f4e6cd696
Autor:
Alok Kapoor, Parth Patel, Soumya Chennupati, Daniel Mbusa, Hammad Sadiq, Sanjeev Rampam, Robert Leung, Megan Miller, Kevin Rivera Vargas, Patrick Fry, Mary Martin Lowe, Christina Catalano, Charles Harrison, John Nicholas Catanzaro, Sybil Crawford, Anne Marie Smith
Publikováno v:
JMIR Cardio, Vol 8, p e49590 (2024)
BackgroundThe gap in anticoagulation use among patients with atrial fibrillation (AF) is a major public health threat. Inadequate patient education contributes to this gap. Patient portal–based messaging linked to educational materials may help bri
Externí odkaz:
https://doaj.org/article/0e9321968b9d488098803726ec7f60ab
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011806 (2023)
Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that target cellular IRFs and/or other innate-immune and stress signaling regulators and suppress the cellular response to viral infection and replication. For vIRF-
Externí odkaz:
https://doaj.org/article/6bc7a849263843dc96979c4eb790cf16
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010676 (2022)
Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma (KS)-associated herpesvirus, is involved etiologically in AIDS-associated KS, primary effusion lymphoma (PEL), and multicentric Castleman's disease, in which both viral latent and lytic func
Externí odkaz:
https://doaj.org/article/79a5ee72fb91437194eb37d67139e521
Autor:
Michael J. LaRiviere, MD, Patricia Mae G. Santos, MD, Joshua A. Jones, MD, John Nicholas Lukens, MD, Neha Vapiwala, MD, Samuel D. Swisher-McClure, MD, MSHP, Abigail T. Berman, MD, MSCE
Publikováno v:
Advances in Radiation Oncology, Vol 5, Iss 2, Pp 289-291 (2020)
Despite the fact that a large portion of medical students pursue training in a cancer-related discipline, oncology is emphasized to a disproportionately lesser extent than are other disciplines in medical school. Medical students have wide gaps in th
Externí odkaz:
https://doaj.org/article/e7bc9b421519461a8c78fa94dcd6f430
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Impaired removal of damaged mitochondria by mitophagy can activate innate immune signaling, but impact on virus replication remains unclear. Here the authors show that viral IRF-1 of human herpesvirus 8 activates mitophagy via interaction with the mi
Externí odkaz:
https://doaj.org/article/0190118766754883975cadf68938321e
Autor:
Francesca Fiorentino, Iqbal Shergill, Manal Kumar, Martin John Connor, Taimur Tariq Shah, Katarzyna Smigielska, Emily Day, Johanna Sukumar, Naveed Sarwar, Michael Gonzalez, Alison Falconer, Natalia Klimowska-Nassar, Martin Evans, Olivia Frances Naismith, Kamalram Thippu Jayaprakash, Derek Price, Shiva Gayadeen, Dolan Basak, Gail Horan, Denise Sheehan, Azman Ibrahim, Cathryn Brock, Rachel A. Pearson, Nicola Anyamene, Catherine Heath, Bhavan Rai, Giles Hellawell, Stuart McCracken, Bijan Khoubehi, Stephen Mangar, Vincent Khoo, Tim Dudderidge, John Nicholas Staffurth, Mathias Winkler, Hashim Uddin Ahmed
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Introduction Survival in men diagnosed with de novo synchronous metastatic prostate cancer has increased following the use of upfront systemic treatment, using chemotherapy and other novel androgen receptor targeted agents, in addition to standard an
Externí odkaz:
https://doaj.org/article/5990ac2cc8ae4ff48516b35753c3f048
Autor:
Mark Manzano, Thomas Günther, Hyunwoo Ju, John Nicholas, Elizabeth T. Bartom, Adam Grundhoff, Eva Gottwein
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Kaposi’s sarcoma-associated herpesvirus (KSHV) causes primary effusion lymphoma (PEL). The cellular transcription factor (TF) interferon (IFN) regulatory factor 4 (IRF4) is an essential oncogene in PEL, but its specific role in PEL and how
Externí odkaz:
https://doaj.org/article/a7cead49aba0468cb9441394698b0a5e
Autor:
John Nicholas Crofts, Norman E. Taylor
Publikováno v:
Journal of Community Safety and Well-Being, Vol 3, Iss 3 (2018)
Externí odkaz:
https://doaj.org/article/d58a01fb16284a90a82c8be979d97110