Zobrazeno 1 - 10
of 19
pro vyhledávání: '"John Neumeyer"'
Autor:
Louise, Lincoln, Ria, Fisher, Michael J, Jackson, Peter, Jenner, John, Neumeyer, Anna W, Sromek, Andrew J, Lees, Sarah, Rose
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 31(9)
The D1/D2 dopamine agonist apomorphine has poor oral bioavailability, necessitating subcutaneous administration in the treatment of Parkinson's disease (PD). Acute subcutaneous injection is used as rescue therapy from "off" periods, whereas continuou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::799ad9abbf8854e3de0acc7fc1117caa
https://pubmed.ncbi.nlm.nih.gov/27133947
https://pubmed.ncbi.nlm.nih.gov/27133947
Autor:
Kazumata K, Dhawan V, Chaly T, Antonini A, Margouleff C, Belakhlef A, John Neumeyer, Eidelberg D
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane (FPCIT) has been synthesized as a dopamine transporter ligand for PET studies. We evaluated the regional brain uptake and the plasma metabolism of [18F]-FPCIT.PET stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5379f0f124d41a2fff0570367a01701c
http://hdl.handle.net/11577/3252213
http://hdl.handle.net/11577/3252213
Autor:
Ishikawa T, Dhawan V, Kazumata K, Chaly T, Mandel F, John Neumeyer, Margouleff C, Babchyck B, Zanzi I, Eidelberg D
Publikováno v:
Europe PubMed Central
SPECT imaging of the dopamine transporter is now an alternative to PET in the quantification of nigrostriatal dopaminergic function. We compared [123I] beta CIT-FP/SPECT and [18F]FDOPA/PET in the assessment of nigrostriatal dopaminergic function in P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::66b3c621a8b8212d1a969ecf8d025bf2
https://pubmed.ncbi.nlm.nih.gov/8917170
https://pubmed.ncbi.nlm.nih.gov/8917170
Publikováno v:
Europe PubMed Central
Iodine-123-beta-CIT is a SPECT radioligand for dopamine and 5-HT transporters with potential use in Parkinson's disease, schizophrenia and cocaine addiction studies. At present, preparation of no-carrier-added (NCA) [123I] beta-CIT is achieved by iod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::db94a217ba5bcbc6d2a15c3d5bb16feb
https://pubmed.ncbi.nlm.nih.gov/7884521
https://pubmed.ncbi.nlm.nih.gov/7884521
Autor:
Jp, Seibyl, Wallace E, Eo, Smith, Stabin M, Rm, Baldwin, Zoghbi S, Zea-Ponce Y, Gao Y, Wy, Zhang, John Neumeyer
Publikováno v:
Europe PubMed Central
SPECT imaging with 123I-labeled methyl 3 beta-(4-iodophenyl)tropane-2 beta-carboxylate ([123I]beta-CIT) in nonhuman primates has shown brain striatal activity, which primarily reflects binding to the dopamine transporter. The biodistribution and calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ed55abfbfc10e7da1b03c92be6790253
https://pubmed.ncbi.nlm.nih.gov/7699474
https://pubmed.ncbi.nlm.nih.gov/7699474
Publikováno v:
Europe PubMed Central
Alkyl and arylalkyl derivatives of the dopamine (DA) D2 antagonist spiperone were prepared and characterized chemically and pharmacologically. They included the N-methyl, N-phenethyl (NPS), and N-p-aminophenethyl (NAPS) derivatives, as well as the al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b473406ecb2896f2d147acc0d9ca25e4
https://pubmed.ncbi.nlm.nih.gov/1435753
https://pubmed.ncbi.nlm.nih.gov/1435753
Autor:
Ao Zhang, John Neumeyer
Publikováno v:
Current Topics in Medicinal Chemistry. 7:341-341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b93345204bff1f06b6ae6d6f8b40a975
https://doi.org/10.2174/156802607779941189
https://doi.org/10.2174/156802607779941189
Publikováno v:
Neurochemical Research; Oct2008, Vol. 33 Issue 10, p2142-2150, 9p
Publikováno v:
Europe PubMed Central
Prompted by conflicting reports of both agonist and antagonist properties of the S-(+)-enantiomer of the potent dopamine agonist R-(-)-N-n-propylnorapomorphine (NPA), we carried out extracellular, single unit recording studies to compare the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::282ec5c8cd763e91407b3b52d6db51f0
https://pubmed.ncbi.nlm.nih.gov/3171980
https://pubmed.ncbi.nlm.nih.gov/3171980
Publikováno v:
Europe PubMed Central
The potent cocaine analog 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)-tropane (CFT, also designated WIN 35,428) was tritiated and evaluated as a molecular probe for cocaine receptors in caudate putamen membranes of cynomolgus monkeys. Kinetic, satura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::20dadb36d54d5adedc53eee2b6850980
https://pubmed.ncbi.nlm.nih.gov/2811854
https://pubmed.ncbi.nlm.nih.gov/2811854