Zobrazeno 1 - 10
of 75
pro vyhledávání: '"John N. Evans"'
Hemodynamic and Biochemical Characteristics of the Aorta in the WKY, SHR, WKHT, and WKHA Rat Strains
Autor:
John N. Evans, Edith D. Hendley, Lise Cloutier, William S. Stirewalt, Jeffrey M. Slaiby, Patricia Nichols, Michael A. Ricci
Publikováno v:
Annals of the New York Academy of Sciences. 800:121-130
This study was designed to characterize the hemodynamic and biochemical properties of the abdominal aorta in four genetically related inbred rat strains that express genetic hypertension and hyperactive behavior in varying combinations. These include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563dc3d344b910eb3f0fdc0372d56c17
https://doi.org/10.1111/j.1749-6632.1996.tb33303.x
https://doi.org/10.1111/j.1749-6632.1996.tb33303.x
Publikováno v:
Methods in Cell Science. 17:245-249
The development of methods to culture intact viable tissue is integral to understanding mechanisms of disease. Mature lung tissue, in particular, is difficult to maintain for any extended period of time in culture due to collapse of airspaces and rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f0a5e60d601149c643ab543e531e08b
https://doi.org/10.1007/bf00986229
https://doi.org/10.1007/bf00986229
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 267:L720-L727
Elevated fractions of inspired O2 induce significant remodeling of the airways and vasculature of the lung. The present study was undertaken to determine the direct effects of altered levels of O2 on protein synthesis and cell proliferation in lung t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5331fb1d4d78e9fc1d6fc20b95876e47
https://doi.org/10.1152/ajplung.1994.267.6.l720
https://doi.org/10.1152/ajplung.1994.267.6.l720
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 264:L74-L79
These studies were undertaken to determine the relationship of early changes in the synthesis rates and contents of collagen, elastin, and soluble tissue protein of pulmonary arteries in rats exposed chronically to normobaric hyperoxia. The growth re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1823ed13b91768000153756c7b1ad4fb
https://doi.org/10.1152/ajplung.1993.264.1.l74
https://doi.org/10.1152/ajplung.1993.264.1.l74
Autor:
John N. Evans, Leslie W. Barger
Publikováno v:
American Review of Respiratory Disease. 144:64-69
We compared the potentiating effect of U46619, a stable thromboxane analogue, on muscarinic contractile responses of rat trachealis and large and small intrapulmonary bronchi. Cylindrical proximal and distal bronchi and midtracheal strips were excise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdfa2fe0ff2c334c293495103daf97f
https://doi.org/10.1164/ajrccm/144.1.64
https://doi.org/10.1164/ajrccm/144.1.64
Autor:
Jean Z. Wong, John J. Mitchell, Sheryl L. White, Linda C. Baldor, Patricia Rippetoe, John N. Evans, Marlene Absher, Janet Woodcock-Mitchell, Kirk M. McHugh, Robert B. Low
Publikováno v:
Scopus-Elsevier
In this study, the expression of smooth muscle actin and myosin was examined in cultures of rat tracheal smooth muscle cells. Protein and mRNA analyses demonstrated that these cells express α- and γ-smooth muscle actin and smooth muscle myosin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f056142d75b8a7eba9970e39d9b143ae
https://pubmed.ncbi.nlm.nih.gov/9612294
https://pubmed.ncbi.nlm.nih.gov/9612294
Publikováno v:
The Journal of biological chemistry. 271(10)
In airway smooth muscle cells ligand binding to the seven-transmembrane endothelin and thrombin receptors stimulates cell growth. Rapid activation of the extracellular regulated kinase 2 and c-Jun NH2-terminal kinase groups of mitogen-activated prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf07fbfed019c674d4eadb8e3af0782a
https://pubmed.ncbi.nlm.nih.gov/8621441
https://pubmed.ncbi.nlm.nih.gov/8621441
Autor:
Chiara Florio, Marlene Absher, John N. Evans, R. W. Samsel, Seymour I. Heisler, Michael D. Kelleher, Mark K. Abe, Julian Solway, Edward T. Naureckas, Marc B. Hershenson
Publikováno v:
American journal of respiratory cell and molecular biology. 12(3)
We previously demonstrated that hyperoxia-exposed immature rats develop airway smooth muscle layer thickening; this remodeling appears partially attributable to smooth muscle hyperplasia. In this study, we tested the hypothesis that excess mitogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdd781e367be7bd7496ae46e2c6619d
https://pubmed.ncbi.nlm.nih.gov/7873192
https://pubmed.ncbi.nlm.nih.gov/7873192
Publikováno v:
The American journal of physiology. 267(2 Pt 1)
Exposure of the lung to elevated oxygen leads to structural and cellular injury followed by extensive tissue remodeling. In vitro models utilizing isolated cells exposed to hyperoxic conditions or exogenously added oxidants may be injurious or stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c8b3d89d0a3be36bd6eab9801b86b2
https://pubmed.ncbi.nlm.nih.gov/8074231
https://pubmed.ncbi.nlm.nih.gov/8074231
Publikováno v:
The Pulmonary Circulation, Normal and Abnormal ISBN: 9781512801736
The Pulmonary Circulation, Normal and Abnormal: Mechanisms, Management, and the National Registry
The Pulmonary Circulation, Normal and Abnormal: Mechanisms, Management, and the National Registry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26e11ddcf41b95b82b8bbca61f07755f
https://doi.org/10.9783/9781512801736-007
https://doi.org/10.9783/9781512801736-007
