Zobrazeno 1 - 10
of 20
pro vyhledávání: '"John N. Davis"'
Autor:
Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 232-244 (2021)
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using establishe
Externí odkaz:
https://doaj.org/article/2b342b9766dc49d78a5a680f8de8cf26
Autor:
Shelby Puckett, Douglas S. Lyles, Teddy E. Kim, Anthony N. van den Pol, David A. Ornelles, John N. Davis, Denise Herpai, Waldemar Debinski, Kailong Zhang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss, Pp 232-244 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using establishe
Publikováno v:
The Journal of Physiology. 597:1605-1625
Key points Excitatory glutamate neurons are sparse in the rostral hypothalamic arcuate nucleus (ARC), the subregion that has received the most attention in the past. In striking contrast, excitatory neurons are far more common (by a factor of 10) in
Autor:
John N. Davis, Ayesha B. Alvero, Gil Mor, Xiaobing Zhang, Eydis Lima, N. Albayrak, Mary Pitruzzello, AN van den Pol
Publikováno v:
Virology
Ovarian cancer is the third most common female cancer, with poor survival in later stages of metastatic spread. We test a chimeric virus consisting of genes from Lassa and vesicular stomatitis viruses, LASV-VSV; the native VSV glycoprotein is replace
Autor:
Michael D. Robek, John N. Davis, Xue Zhang, Tingting Zhang, Andrea Marzi, Anthony N. van den Pol, Anthony M. Marchese
Publikováno v:
J Virol
Given that the Ebola virus (EBOV) infects a wide array of organs and cells yet displays a relative lack of neurotropism, we asked whether a chimeric vesicular stomatitis virus (VSV) expressing the EBOV glycoprotein (GP) might selectively target brain
Publikováno v:
The Journal of Applied Management and Entrepreneurship. 20:6-24
Zika virus (ZIKV), a positive-sense RNA flavivirus, has attracted considerable attention recently for its potential to cause serious neurological problems, including microcephaly, cortical thinning, and blindness during early development. Recent find
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d8783a5ff652b13b67ab98bd143c86
http://hdl.handle.net/10281/157344
http://hdl.handle.net/10281/157344
Publikováno v:
Journal of Virology. 87:6644-6659
Metastatic malignant melanoma remains one of the most therapeutically challenging forms of cancer. Here we test replication-competent vesicular stomatitis viruses (VSV) on 19 primary human melanoma samples and compare these infections with those of n
Publikováno v:
Journal of virology. 91(6)
Recombinant vesicular stomatitis virus (VSV)-based chimeric viruses that include genes from other viruses show promise as vaccines and oncolytic viruses. However, the critical safety concern is the neurotropic nature conveyed by the VSV glycoprotein.
Autor:
Kelly L. Gorres, George Miller, John N. Davis, Sara Ornaghi, Michael J. Paidas, Anthony N. van den Pol
Cytomegalovirus (CMV) infection can generate debilitating disease in immunocompromised individuals and neonates. It is also the most common infectious cause of congenital birth defects in infected fetuses. Available anti-CMV drugs are partially effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ba22800b588141ab1624adb63bb8ca
https://europepmc.org/articles/PMC5102808/
https://europepmc.org/articles/PMC5102808/