Zobrazeno 1 - 10
of 156
pro vyhledávání: '"John N. Brady"'
Autor:
Cynthia A. Pise-Masison, Kyung-Jin Jung, John N. Brady, Claudio Fenizia, Katherine M. McKinnon, Dustin C. Edwards
Publikováno v:
Viruses, Vol 3, Iss 10, Pp 1815-1835 (2011)
Human T-cell leukemia virus type-1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL), an aggressive and highly chemoresistant malignancy. Rho family GTPases regulate multiple signaling pathways in tumorigenesis: cytoskeletal organizati
Externí odkaz:
https://doaj.org/article/0746c52d29624c1e96a3b2b48e4992e5
Autor:
Sébastien A Chevalier, Jocelyn Turpin, Anne Cachat, Philippe V Afonso, Antoine Gessain, John N Brady, Cynthia A Pise-Masison, Renaud Mahieux
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003917 (2014)
Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in
Externí odkaz:
https://doaj.org/article/73e1715ede6243709166bd62b0e813e8
Autor:
Sébastien A Chevalier, Stéphanie Durand, Arindam Dasgupta, Michael Radonovich, Andrea Cimarelli, John N Brady, Renaud Mahieux, Cynthia A Pise-Masison
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41003 (2012)
Human T-cell Lymphotropic Viruses type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma. Although associated with lymphocytosis, HTLV-2 infection is not associated with any malignant hematological disease. Similarly, no infection
Externí odkaz:
https://doaj.org/article/d51b8c86ff8648239f1431f871855ad3
Autor:
Chloé Journo, Josina Filipe, Frédégonde About, Sébastien A Chevalier, Philippe V Afonso, John N Brady, David Flynn, Frédéric Tangy, Alain Israël, Pierre-Olivier Vidalain, Renaud Mahieux, Robert Weil
Publikováno v:
PLoS Pathogens, Vol 5, Iss 7, p e1000521 (2009)
Nuclear factor (NF)-kappaB is a major survival pathway engaged by the Human T-Lymphotropic Virus type 1 (HTLV-1) Tax protein. Tax1 activation of NF-kappaB occurs predominantly in the cytoplasm, where Tax1 binds NF-kappaB Essential Modulator (NEMO/IKK
Externí odkaz:
https://doaj.org/article/372ff74895804ec8ae6b73c5a6028ff1
Autor:
Kyung-Jin Jung, Dustin Edwards, Claudio Fenizia, Cynthia A. Pise-Masison, John N. Brady, Katherine McKinnon
Publikováno v:
Viruses, Vol 3, Iss 10, Pp 1815-1835 (2011)
Viruses; Volume 3; Issue 10; Pages: 1815-1835
Viruses
Viruses; Volume 3; Issue 10; Pages: 1815-1835
Viruses
Human T-cell leukemia virus type-1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL), an aggressive and highly chemoresistant malignancy. Rho family GTPases regulate multiple signaling pathways in tumorigenesis: cytoskeletal organizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47837ecb1807864a8a08890711377fd4
http://www.mdpi.com/1999-4915/3/10/1815/
http://www.mdpi.com/1999-4915/3/10/1815/
Autor:
William R. Welch, Ke Hao, Michael E. Johnson, J. Carl Barrett, Wing Hung Wong, Howard Donninger, Tomas Bonome, Mike Randonovich, Michael J. Birrer, Goli Samimi, Laurent Ozbun, John N. Brady, Kwong Kwok Wong, Aaron Bell, Cindy Pise-Masison, Dong Choon Park, Daniel K.P. Yip, Vinod Vathipadiekal, Ross S. Berkowitz, Samuel C. Mok
Publikováno v:
Cancer Cell. 16(6):521-532
Ovarian cancer is the most lethal gynecologic cancer, and this is largely related to its late diagnosis. High grade serous cancers often initially respond to chemotherapy, resulting in a better survival rate, compared to other ovarian carcinoma subty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a33e6a1a414d948971c1eb6c268e66
Autor:
Kathleen M. Dohoney, John C. Morris, John E. Janik, John N. Brady, Cynthia A. Pise-Masison, Deirdre O'Mahony, Min-Jung Lee, Michael F. Radonovich, Jane B. Trepel, Thomas A. Waldmann
Publikováno v:
Blood. 113:4016-4026
Adult T-cell leukemia/lymphoma (ATL) is an aggressive and fatal disease. We have examined 32 patients with smoldering, chronic, lymphoma and acute leukemia using Affymetrix HG-U133A2.0 arrays. Using the BRB array program, we identified genes differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8358c13cbffd4fab5a0a17ce37379df
https://doi.org/10.1182/blood-2008-08-175901
https://doi.org/10.1182/blood-2008-08-175901
Publikováno v:
Journal of Virology. 83:2140-2153
Kaposi's sarcoma-associated herpesvirus (KSHV/human herpesvirus 8) is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and a subset of multicentric Castleman's diseases. KS typically presents as a multicentric angiopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d5a0436ba02124f0e4d2fca95f0d08
https://doi.org/10.1128/jvi.01871-08
https://doi.org/10.1128/jvi.01871-08
Autor:
Soo-Jin Jeong, Cynthia A. Pise-Masison, Katerina Gurova, John N. Brady, Kyung-Jin Jung, Keven Huang, Arindam Dasgupta
Publikováno v:
Journal of Virology. 82:8537-8547
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of the aggressive and fatal disease adult T-cell leukemia. Previous studies have demonstrated that the HTLV-1-encoded Tax protein inhibits the function of tumor suppressor p53 through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a602a640e0d93ee46cd8fe6ce27c1b3
https://doi.org/10.1128/jvi.00690-08
https://doi.org/10.1128/jvi.00690-08
Autor:
John N. Brady, Mike Randonovich, J. Carl Barrett, Douglas A. Levine, Laurent Ozbun, Joanna H. Shih, Michael J. Birrer, Cynthia A. Pise-Masison, Tomas Bonome, Jeff Boyd, Faina Bogomolniy
Publikováno v:
Cancer Research. 68:5478-5486
Despite the existence of morphologically indistinguishable disease, patients with advanced ovarian tumors display a broad range of survival end points. We hypothesize that gene expression profiling can identify a prognostic signature accounting for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f2bf4f00198f359f5d04946323f1be
https://doi.org/10.1158/0008-5472.can-07-6595
https://doi.org/10.1158/0008-5472.can-07-6595