Zobrazeno 1 - 10
of 10
pro vyhledávání: '"John Morris Sullivan"'
Autor:
Lew Truex, Jay K. Herman, John Morris Sullivan, Kanchan Narwani, Ellen A. Cannady, Thomas Ryan, Mark A. Carfagna
Publikováno v:
Regulatory Toxicology and Pharmacology. 92:458-471
Baricitinib is a potent and selective Janus kinase (JAK)1 and JAK2 inhibitor, and is approved for the treatment of moderately to severely active RA in adults in Europe, Japan, and other countries. This study evaluated the carcinogenic potential of ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82eb9c2e0ff18d96311a2b53fa68b1a1
https://doi.org/10.1016/j.yrtph.2017.11.020
https://doi.org/10.1016/j.yrtph.2017.11.020
Autor:
Hui-Rong Qian, Tao Wei, Josef G. Heuer, Kathleen M. Heinz-Taheny, Shannon M Harlan, Derek D. Yang, John Morris Sullivan, Jeffrey S. Boyles, Dianna L. Jaqua, Matthew D. Breyer, Derrick R. Witcher, Jonathan M. Wilson
Publikováno v:
American Journal of Physiology-Renal Physiology. 312:F951-F962
Transforming growth factor-alpha (TGFA) has been shown to play a role in experimental chronic kidney disease associated with nephron reduction, while its role in diabetic kidney disease (DKD) is unknown. We show here that intrarenal TGFA mRNA express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b27ff6c3129951dd87e3467722c37a
https://doi.org/10.1152/ajprenal.00443.2016
https://doi.org/10.1152/ajprenal.00443.2016
Autor:
Martin S. Cramer, Dianna L. Jaqua, Shannon M Harlan, Hana E. Baker, Tao Wei, Josef G. Heuer, John Morris Sullivan, Zhonghua Qi, Kathleen M. Heinz-Taheny, Tatiyana L. Shiyanova, Matthew D. Breyer
Publikováno v:
Journal of the American Society of Nephrology : JASN. 29(2)
Progress in research and developing therapeutics to prevent diabetic kidney disease (DKD) is limited by a lack of animal models exhibiting progressive kidney disease. Chronic hypertension, a driving factor of disease progression in human patients, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7a72d7cbfb08aef738890769df7105
https://pubmed.ncbi.nlm.nih.gov/29061652
https://pubmed.ncbi.nlm.nih.gov/29061652
Autor:
Amy L. Usborne, John Morris Sullivan, Aaron T. Smith, Jennie L. Walgren, Steven K. Engle, David E. Watson
Publikováno v:
Toxicologic Pathology. 42:195-203
Consistent, sensitive biomarkers of exocrine pancreatic injury (EPIJ) in animal models and humans have historically represented a poorly met need for investigators and clinicians. Experimental design: Sprague-Dawley CD/International Genetic Standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9ab763d43579905ea4fbcbfae6bd61
https://doi.org/10.1177/0192623313512030
https://doi.org/10.1177/0192623313512030
Autor:
A. Eric Schultze, John Morris Sullivan
Publikováno v:
Veterinary Clinical Pathology. 36:123-136
Background: Veterinary clinical and anatomic pathologists play a critical role in assessing the safety of new molecules. The process for evaluation of candidate molecules in drug discovery may vary markedly, depending on the unique characteristics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443ffe9fe6cf822b7c843ef1973aacb5
https://doi.org/10.1111/j.1939-165x.2007.tb00198.x
https://doi.org/10.1111/j.1939-165x.2007.tb00198.x
Autor:
Jamie L. Blackbourne, Amy L. Usborne, John Morris Sullivan, James T Meehan, John L. Vahle, Richard A. Byrd, Annick Prefontaine, Jennifer A. Martin, Florence Poitout-Belissent
Publikováno v:
Toxicologic pathology. 43(8)
Glucagon-like peptide-1 (GLP-1) receptor agonist therapy has been implicated as a possible risk factor for acute pancreatitis in patients with type 2 diabetes. Dulaglutide is a long-acting GLP-1 receptor agonist in development for treatment of type 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87d244541824b5e51f89b684617030c
https://pubmed.ncbi.nlm.nih.gov/26269615
https://pubmed.ncbi.nlm.nih.gov/26269615
The exocrine pancreas is strategically located in the anterior abdominal cavity adjacent to the stomach, duodenum, and liver to enable secretion of digestive enzymes into the small intestine, and to convert ingesta into absorbable proteins, carbohydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9946c64b86661177e869ad150552c5
https://doi.org/10.1016/b978-0-12-415759-0.00057-1
https://doi.org/10.1016/b978-0-12-415759-0.00057-1
'Have You Seen This?' Abnormal Lymphocytes in Simian Retrovirus (Type D)—Infected Cynomolgus Monkeys
Publikováno v:
Toxicologic Pathology. 27:468-470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe5ee658a615e9fa4669e558396f9dd
https://doi.org/10.1177/019262339902700412
https://doi.org/10.1177/019262339902700412
Autor:
Roy L. Kerlin, Terry Peters, Darlene Dixon, Gary A. Boorman, Michael R. Elwell, Karen S. Regan, Daniel Morton, John Morris Sullivan
Publikováno v:
Toxicologic pathology. 31(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7852e5c461bfe996be486adcf48fd8
https://pubmed.ncbi.nlm.nih.gov/14585740
https://pubmed.ncbi.nlm.nih.gov/14585740
Autor:
Karen S. Regan, Roy L. Kerlin, Daniel Morton, Darlene Dixon, Terry Peters, Michael R. Elwell, Gary A. Boorman, John Morris Sullivan
Publikováno v:
Toxicologic Pathology. 32:124-125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8167bcf913f55b76e39698c047a83f1
https://doi.org/10.1080/01926230490279402
https://doi.org/10.1080/01926230490279402