Zobrazeno 1 - 10
of 30
pro vyhledávání: '"John Miao"'
Autor:
Yao Yang, Jihan Zhou, Zipeng Zhao, Geng Sun, Saman Moniri, Colin Ophus, Yongsoo Yang, Ziyang Wei, Yakun Yuan, Cheng Zhu, Yang Liu, Qiang Sun, Qingying Jia, Hendrik Heinz, Jim Ciston, Peter Ercius, Philippe Sautet, Yu Huang, Jianwei (John) Miao
Heterogeneous catalysts play a key role in the chemical and energy industries1. To date, most industrial-scale heterogeneous catalytic reactions have relied on nanocatalysts2,3. However, despite significant progress from theoretical, experimental and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977795b605c87d958c768a487c813d6e
https://doi.org/10.21203/rs.3.rs-1471299/v1
https://doi.org/10.21203/rs.3.rs-1471299/v1
Autor:
Arjun Rana, Chen-Ting Liao, Ezio Iacocca, Ji Zou, Minh Pham, Xingyuan Lu, Emma-Elizabeth Cating Subramanian, Yuan Hung Lo, Sinéad Ryan, Charles Bevis, Robert Karl, Andrew Glaid, Jeffrey Rable, Pratibha Mahale, Joel Hirst, Thomas Ostler, William Liu, Colum O’Leary, Young-Sang Yu, Karen Bustillo, Hendrik Ohldag, David Shapiro, Sadegh Yazdi, Thomas Mallouk, Stanley Osher, Henry Kapteyn, Vincent Crespi, John Badding, Yaroslav Tserkovnyak, Margaret Murnane, Jianwei (John) Miao
Topological magnetic monopoles, also known as hedgehogs or Bloch points, are three-dimensional (3D) nonlocal spin textures that are robust to thermal and quantum fluctuations due to their topology1-4. Understanding their properties is of both fundame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d817697fdefa4047e33e2af143e827
https://doi.org/10.21203/rs.3.rs-1413330/v1
https://doi.org/10.21203/rs.3.rs-1413330/v1
Autor:
Chen-Ting Liao, Arjun Rana, Ezio Iacocca, Ji Zou, Minh Pham, Xingyuan Lu, Emma-Elizabeth Cating Subramanian, Yuan Hung Lo, Sinéad A. Ryan, Charles S. Bevis, Robert M. Karl, Andrew J. Glaid, Jeffrey Rable, Pratibha Mahale, Joel Hirst, Thomas Ostler, William Liu, Colum M. O'Leary, Young-Sang Yu, Karen Bustillo, Hendrik Ohldag, David A. Shapiro, Sadegh Yazdi, Thomas E. Mallouk, Stanley J. Osher, Henry C. Kapteyn, Vincent H. Crespi, John V. Badding, Yaroslav Tserkovnyak, Jianwei (John) Miao, Margaret M. Murnane
Publikováno v:
Optica High-brightness Sources and Light-driven Interactions Congress 2022.
We developed soft x-ray vector ptychography at 10 nm spatial resolution without requiring a priori knowledge, which is then used to quantitatively image 3D magnetization vector fields of topological magnetic monopoles and their interactions.
Autor:
Joseph Tringali, Christina Amidei, Patrick Y. Wen, John Loewy, Wenya Linda Bi, Kyla A. Truman, Nathan Demars, Leah Seften, Rimas V. Lukas, Jill Buck, E. Antonio Chiocca, Nira Hadar, Dan Triggs, Arnold Gelb, Kamal Chadha, Ganesh Rao, Grace E. Park, James Grant, Pierpaolo Peruzzi, Taylor Estupinan, David A. Reardon, Clark C. Chen, Laurence J.N. Cooper, John Miao
Publikováno v:
Neuro Oncol
Background Veledimex (VDX)-regulatable interleukin-12 (IL-12) gene therapy in recurrent glioblastoma (rGBM) was reported to show tumor infiltration of CD8+ T cells, encouraging survival, but also up-regulation of immune checkpoint signaling, providin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f3b57f3cf7f1182cf02ed4925d31a2
https://europepmc.org/articles/PMC9159462/
https://europepmc.org/articles/PMC9159462/
Autor:
Jill Buck, Yunxia Wang, Nira Hadar, Laurence J.N. Cooper, Nathan Demars, John Miao, John Loewy, John S. Yu, Nancy Ann Oberheim Bush, Rimas V. Lukas, Joseph Landolfi, Arnold Gelb, Robert Cavaliere, Sylvia Kurz, E. Antonio Chiocca
Publikováno v:
Neuro Oncol
Ad-RTS-hIL-12 (Ad) is a gene therapy candidate for intratumoral (IT) delivery that conditionally expresses IL-12 (IL-12) under the transcriptional control of orally administered veledimex (V) acting via the RheoSwitch Therapeutic Systemâ gene switch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c81a9468f41bd3331cc06fa6cc0f2f
https://europepmc.org/articles/PMC7650356/
https://europepmc.org/articles/PMC7650356/
Autor:
Jinlong Gao, Jihan Zhou, Zhenyu Liu, Yonggang Yao, Miaolun Jiao, Peng Zhang, Zhennan Huang, Reza Shahbazian-Yassar, Liangbing Hu, David Morris, Tangyuan Li, Zou Finfrock, Chao Wang, Guofeng Wang, Jianwei John Miao, Yimin Mao, Pengfei Xie
Publikováno v:
Science Advances
We developed a computationally aided alloy synthesis in the multi-element space toward highly efficient and durable catalysts.
Multi-elemental alloy nanoparticles (MEA-NPs) hold great promise for catalyst discovery in a virtually unlimited compo
Multi-elemental alloy nanoparticles (MEA-NPs) hold great promise for catalyst discovery in a virtually unlimited compo
Autor:
Nate Demars, John S. Yu, Kamal Chadha, John Loewy, Nancy Ann Oberheim-Bush, Rimas V. Lukas, Christina Amidei, Jill Buck, Nira Hadar, Taylor Estupinan, Laurence J.N. Cooper, Robert Cavaliere, E. Antonio Chiocca, Christine Cordova, Clark C. Chen, Joseph Landolfi, John Miao
Publikováno v:
Neuro Oncol
Ad-RTS-hIL-12(Ad) is a gene therapy candidate conditionally expressing IL-12 under the transcriptional control of veledimex(V) acting via the RheoSwitch Therapeutic System® gene switch. Veledimex plasma and tumor PK demonstrated a dose-response rela
Autor:
Nathan Demars, Yunxia Wang, Laurence J.N. Cooper, Amy Smith, John Miao, Ennio Antonio Chiocca, Arnold Gelb, Jill Buck, Sylvia Kurz, Rimas V. Lukas, John S. Yu, John Zhou, Ganesh Rao, Joseph Landolfi
Publikováno v:
Neuro Oncol
Ad-RTS-hIL-12 (Ad) is a novel gene therapy, conditionally expressing IL-12 via the RheoSwitch Therapeutic System® (RTS®) gene switch under control of an oral activator ligand, veledimex (V). We previously reported results from 51 subjects (NCT02026
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ceb0131cf8d19db1b45fb83fa8e382e
https://europepmc.org/articles/PMC6847372/
https://europepmc.org/articles/PMC6847372/
Autor:
Amy Smith, Ganesh Rao, Nathan Demars, John Zhou, Rimas V. Lukas, Ennio Antonio Chiocca, Arnold Gelb, Laurence J.N. Cooper, John Miao, Jill Buck
Publikováno v:
Neuro Oncol
Monotherapy with intratumoral Ad-RTS-hIL-12 (Ad), a novel gene therapeutic conditionally expressing IL-12 under the transcriptional control of oral veledimex (V, 20 mg) acting via the proprietary RheoSwitch Therapeutic System® (RTS®), was shown in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f1a8ae9159db78ba3a6855c2355437
https://europepmc.org/articles/PMC6847446/
https://europepmc.org/articles/PMC6847446/
Publikováno v:
Clinical Pharmacology in Drug Development. 6:246-257
Major obstacles to developing effective immunotherapy are the ability of tumors to escape the immune system and the toxicity associated with systemic administration. To overcome these challenges, a gene delivery platform technology, RheoSwitch Therap