Zobrazeno 1 - 10
of 31
pro vyhledávání: '"John Mallon"'
Autor:
Jenny Zheng, John Mallon, Alex Lammers, Theopi Rados, Thomas Litschel, Edmund R. R. Moody, Diego A. Ramirez-Diaz, Amy Schmid, Tom A. Williams, Alexandre W. Bisson-Filho, Ethan Garner
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTAcross the domains of life, actin homologs are integral components of many essential processes, such as DNA segregation, cell division, and cell shape determination. Archaeal genomes, like those of bacteria and eukaryotes, also encode actin h
Externí odkaz:
https://doaj.org/article/9e8ae4a3f3054c1f8f30c151a05fcb87
Autor:
Dominic Francis John Mallon, Justin Callaghan, Chloe Goodred, Brittany Rose Stevenson, Jack Bourke
Publikováno v:
The journal of allergy and clinical immunology. In practice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616627cddae4c9ea9eb8ffc9582d6665
https://pubmed.ncbi.nlm.nih.gov/36410661
https://pubmed.ncbi.nlm.nih.gov/36410661
Autor:
Yanbo Wang, Scott Bailey, Taekjip Ha, Digvijay Singh, Myung Hyun Jo, Haobo Wang, John Mallon, Boyang Hua
Publikováno v:
Proc Natl Acad Sci U S A
CRISPR-Cas9 from Streptococcus pyogenes is an RNA-guided DNA endonuclease, which has become the most popular genome editing tool. Coordinated domain motions of Cas9 prior to DNA cleavage have been extensively characterized but our understanding of Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f672a0d79660ea56c44528024bf75b
https://doi.org/10.1073/pnas.2010650118
https://doi.org/10.1073/pnas.2010650118
Akademický článek
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Publikováno v:
Journal of the Royal Statistical Society Series A: Statistics in Society. 184:1600-1601
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f6701b98d28a7eebf1c248b7c4e7c5b
https://doi.org/10.1111/rssa.12726
https://doi.org/10.1111/rssa.12726
Autor:
Yanbo Wang, Taekjip Ha, Scott Bailey, Haobo Wang, Xinyu Ashlee Feng, Wayne Taylor Cottle, John Mallon, Momčilo Gavrilov
Publikováno v:
Mol Cell
Cas9 in complex with a programmable guide RNA targets specific double-stranded DNA for cleavage. By harnessing Cas9 as a programmable loader of superhelicase to genomic DNA, here we report a physiological-temperature DNA FISH method termed Genome Oli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6125f6ed09c745875c8944be26825cdb
https://pubmed.ncbi.nlm.nih.gov/33657402
https://pubmed.ncbi.nlm.nih.gov/33657402
Autor:
Yanbo Wang, Wayne T. Cottle, Haobo Wang, Xinyu A. Feng, John Mallon, Momcilo Gavrilov, Roger Zou, Scott Bailey, Taekjip Ha
Publikováno v:
Biophysical Journal. 121:20a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e7f708ef82ef2803f2af4179a0d980d
https://doi.org/10.1016/j.bpj.2021.11.2610
https://doi.org/10.1016/j.bpj.2021.11.2610
Autor:
Yanbo Wang, Anustup Poddar, Digvijay Singh, Taekjip Ha, John Mallon, Scott Bailey, Ramreddy Tippana, Olivia Yang
Publikováno v:
Proceedings of the National Academy of Sciences. 115:5444-5449
CRISPR-Cas9, which imparts adaptive immunity against foreign genomic invaders in certain prokaryotes, has been repurposed for genome-engineering applications. More recently, another RNA-guided CRISPR endonuclease called Cpf1 (also known as Cas12a) wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441115b4d1928e7d6e68a4feec3dc317
https://doi.org/10.1073/pnas.1718686115
https://doi.org/10.1073/pnas.1718686115
Autor:
Scott Bailey, Sergey Shmakov, Ekaterina Savitskaya, John Mallon, Kirill A. Datsenko, Konstantin Kuznedelov, Ishita Jain, Brian Bothner, Alexander F. Yakunin, Konstantin Severinov, Ekaterina Semenova, Monika Tokmina-Lukaszewska, Vladimir Mekler, Sofia Lemak
Publikováno v:
Nucleic Acids Research
The Escherichia coli type I-E CRISPR-Cas system Cascade effector is a multisubunit complex that binds CRISPR RNA (crRNA). Through its 32-nucleotide spacer sequence, Cascade-bound crRNA recognizes protospacers in foreign DNA, causing its destruction d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194e031d0c6c9da426426301553d1ac4
https://doi.org/10.1093/nar/gkw914
https://doi.org/10.1093/nar/gkw914
Autor:
Damon Ceylan, Scott Bailey, Taekjip Ha, Anustup Poddar, John Mallon, Jingyi Fei, Yanbo Wang, Olivia Yang, Digvijay Singh
Publikováno v:
Nature structuralmolecular biology. 25(4)
Cas9 (from Streptococcus pyogenes) in complex with a guide RNA targets complementary DNA for cleavage. Here, we developed a single-molecule FRET analysis to study the mechanisms of specificity enhancement of two engineered Cas9s (eCas9 and Cas9-HF1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb2ee18cac13e4c00921ccd9a7a196c
https://pubmed.ncbi.nlm.nih.gov/29622787
https://pubmed.ncbi.nlm.nih.gov/29622787