Výsledky vyhledávání - "John M. Toomasian"

Inflammatory Effects of Blood–Air Interface in a Porcine Cardiopulmonary Bypass Model

Autor: Megan A. Coughlin, John M. Toomasian, Robert H. Bartlett, Azmath Mohammed, Amalia E. Gomez-Rexrode, Jonathan W. Haft, Benjamin D. Carr, Alvaro Rojas-Pena, Thomas J Johnson

Publikováno v: ASAIO J

Cardiopulmonary bypass (CPB) causes a systemic inflammatory response syndrome (SIRS) associated with multiorgan injury. A model was developed to test whether a blood-air interface in the CPB circuit causes blood element activation and inflammation. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fd9261005a1b443ffbea62b534adb7
https://doi.org/10.1097/mat.0000000000000938

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Tidal Flow Perfusion for the Artificial Placenta: A Paradigm Shift

Autor: Marie S. Cornell, Mark M.P. Jeakle, Alvaro Rojas-Pena, Taylor L. Fegan, Samantha C. Toor, Peter R. Kordell, Jacqueline C. Kading, Rachel A. Pfannes, Mark W. Langley, Mary Reiber, George B. Mychaliska, John M. Toomasian, Robert H. Bartlett, Gergely Lautner

Publikováno v: ASAIO J

The modalities of vascular access for the extracorporeal artificial placenta (AP) have undergone many iterations over the past decade. We hypothesized that single lumen cannulation (SLC) of the jugular vein using tidal flow extracorporeal life (ECLS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be3f9e2f804adc72bd5dad3ab1b7305
https://doi.org/10.1097/mat.0000000000001077

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Novel Leukocyte Modulator Device Reduces the Inflammatory Response to Cardiopulmonary Bypass

Autor: Deborah A. Buffington, John M. Toomasian, Thomas M. Johnson, Alvaro Rojas-Pena, Jonathan W. Haft, Kimberly A. Johnston, H. David Humes, Angela J. Westover

Publikováno v: ASAIO J

Leukocyte (LE) activation during cardiopulmonary bypass (CPB) promotes a systemic inflammatory response that contributes to organ injury and postoperative organ dysfunction. A leukocyte modulatory device (L-MOD) for use during (and after) CPB to limi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e1818de3538091e95b2df26df3bbf7
https://doi.org/10.1097/mat.0000000000000822

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CO2clearance by membrane lungs

Autor: Andreas Kaesler, Liqun Sun, John M. Toomasian, Piyumindri Fernando, Alex J. Thompson, Robert H. Bartlett

Publikováno v: Perfusion. 33:249-253

Introduction:Commercial membrane lungs are designed to transfer a specific amount of oxygen per unit of venous blood flow. Membrane lungs are much more efficient at removing CO2than adding oxygen, but the range of CO2transfer is rarely reported.Metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e7ab769f37651a9f8a8220997be335e
https://doi.org/10.1177/0267659117736379

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A Membrane Lung Design Based on Circular Blood Flow Paths

Autor: Joseph A. Potkay, Alex J. Thompson, Joseph L. Bull, Robert H. Bartlett, Peter C. Schlanstein, Ronald B. Hirschl, Andreas Kaesler, John M. Toomasian, Jutta Arens, Hannah Cheriyan, Uditha Piyumindri Fernando

Publikováno v: ASAIO Journal. 63:637-643

Current hollow fiber membrane lungs feature a predominantly straight blood path length across the fiber bundle, resulting in limited oxygen transfer efficiency due to the diffusion boundary layer effect. Using computational fluid dynamics and optical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c581fad6d72e406ef6fa82830de0061
https://doi.org/10.1097/mat.0000000000000616

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