Zobrazeno 1 - 5
of 5
pro vyhledávání: '"John M. Temperley"'
Publikováno v:
Gut. 12:825-829
Pentagastrin is rapidly removed from the circulation of the dog. It is excreted by the liver into the bile, largely in an inactivated form. Preliminary results indicate that it meets the same fate in man.
Autor:
John M. Temperley
Publikováno v:
International Journal of Clinical Practice. 28:217-219
Publikováno v:
The British journal of surgery. 61(1)
Pentagastrin is deamidated to pentagastrin acid by high-speed supernatant preparations obtained from rat, dog and human liver. The product, which contains all the amino acids in the parent substance, is biologically inactive. Experiments with pentaga
Publikováno v:
Gut. 12(5)
Experiments on dogs and rats showed that synthetic human gastrin I was inactivated in the small bowel but not in the liver, whereas pentagastrin was rapidly inactivated by the liver. Similar results were obtained with tissue homogenates. The signific
Publikováno v:
Nature. 228:58-59
RADIOIODINATED polypeptide hormones are widely used as tracers for both radioimmunoassay and in vivo metabolic studies. The process of iodination may induce gross chemical changes which are detectable by physico-chemical techniques, but such techniqu