Zobrazeno 1 - 3
of 3
pro vyhledávání: '"John M. Replogle"'
Autor:
Anthony Letai, Stephen J. Lippard, John M. Replogle, Angelika Amon, Jeremy Ryan, James M. McFarland, Wen Zhou, Adrianna E. Amaro, Jason M. Sheltzer, Mariana Villalobos-Ortiz, Uri Ben-David, Ömer H. Yilmaz
Publikováno v:
Proc Natl Acad Sci U S A
Aneuploidy, defined as whole chromosome gains and losses, is associated with poor patient prognosis in many cancer types. However, the condition causes cellular stress and cell cycle delays, foremost in G1 and S phase. Here, we investigate how aneupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4d6a39075df7abe99a035b136944d2
https://doi.org/10.1073/pnas.2009506117
https://doi.org/10.1073/pnas.2009506117
Autor:
Charles A. Whittaker, Duanduan Ma, Xiaofeng A. Su, James F. Amatruda, James V. Parsons, Angelika Amon, Kimberly Stegmaier, John M. Replogle
Publikováno v:
Cancer Research. 80:B52-B52
Many tumor types harbor specific chromosome gains or losses. In Ewing sarcoma (ES) chromosome 8 gain is extremely common, indicating that this trisomy drives tumorigenesis. However, in primary cells, whole chromosome gains and losses are universally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b45f9c3a2994e4eb878de2631ab758
https://doi.org/10.1158/1538-7445.pedca19-b52
https://doi.org/10.1158/1538-7445.pedca19-b52
Autor:
Nicole M. Sayles, Zuzana Storchova, Jason M. Sheltzer, Julie H. Ko, Angelika Amon, Colleen M. Meehl, Nicole C. Habibe Burgos, John M. Replogle, Erica S. Chung, Verena Passerini
Publikováno v:
PMC
Aneuploidy is a hallmark of cancer, although its effects on tumorigenesis are unclear. Here, we investigated the relationship between aneuploidy and cancer development using cells engineered to harbor single extra chromosomes. We found that nearly al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916a16040f256a8322aee6bb986bd689
https://orcid.org/0000-0003-2735-8195
https://orcid.org/0000-0003-2735-8195
