Zobrazeno 1 - 10
of 46
pro vyhledávání: '"John M. Polo"'
Autor:
M Jeff Bergen, Chien-Hsiung Pan, Catherine E Greer, Harold S Legg, John M Polo, Diane E Griffin
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10297 (2010)
A variety of vaccine platforms are under study for development of new vaccines for measles. Problems with past measles vaccines are incompletely understood and underscore the need to understand the types of immune responses induced by different types
Externí odkaz:
https://doaj.org/article/f6c5fc98738144dabb8a0cabc0520c8b
Autor:
Silvia Perri, Harold Legg, Michael Vajdy, Grazia Galli, Giulietta Saletti, John M. Polo, Susan W. Barnett, Gillis R. Otten, Rino Rappuoli, Yasushi Uematsu, Ying Lian, Catherine Greer
Publikováno v:
Clinical and Vaccine Immunology
Antivector immunity has been recognized as a potential caveat of using virus-based vaccines. In the present study, an alphavirus-based replicon particle vaccine platform, which has demonstrated robust immunogenicity in animal models, was tested for e
Publikováno v:
Revista de Ingeniería, Issue: 28, Pages: 105-99, Published: NOV 2008
Este artículo reporta el potencial de energía obtenido de corrientes de marea a lo largo de la costa colombiana en una extensión aproximada de 3 100 km. Se utilizan imágenes Landsat y sistemas de información geográfica para digitalizar la líne
Autor:
Kevin Crawford, Michael Houghton, Mark Wininger, Colin S. McCoin, Hall John A, John M. Polo, Doris Coit, Michael Vajdy, Christine Dong, Angelica Medina-Selby, Yi-Fei Zhu, Stephen R. Coates, Debbie Drane, Philip Ng, Taewoo Kwon, Jang Han, Yin-Ling Lin, Mark Selby, David Chien
Publikováno v:
Journal of Virology. 82:7492-7503
Broad, multispecific CD4 + and CD8 + T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chronic HCV patients with a favorabl
Autor:
Harold Legg, Zequn Tang, Yasushi Uematsu, Michael Vajdy, Catherine Greer, John M. Polo, Fengmin Zhou, J. Zur Megede, Amanda Goodsell
Publikováno v:
Scandinavian Journal of Immunology. 66:645-653
No licensed vaccines are available to protect against parainfluenza virus type 3 (PIV3), a significant health risk for infants. In search of a safe vaccine, we used an alphavirus-based chimeric vector, consisting of Sindbis virus (SIN) structural pro
Autor:
Fengmin Zhou, Tony Tang, Harold Legg, Paul A. Luciw, Jan zur Megede, Derek T. O'Hagan, Michael Vajdy, Susan W. Barnett, John M. Polo, Catherine Greer, John J. Donnelly, Soumi Gupta
Publikováno v:
AIDS Research and Human Retroviruses. 22:993-997
Mucosal and systemic transmission of HIV is prevalent. Therefore, mucosal followed by parenteral immunizations with chimeric vs. complete alphavirus-based replicon particles, encoding an HIV envelope glycoprotein, were tested. Female rhesus macaques
Autor:
Alejandra V. E. Capozzo, Eileen M. Barry, Marcela F. Pasetti, Myron M. Levine, John M. Polo, Jeffrey B. Ulmer, Karina Ramirez
Publikováno v:
The Journal of Immunology. 176:5671-5681
Infants younger than age 9 mo do not respond reliably to the live attenuated measles vaccine due the immaturity of their immune system and the presence of maternal Abs that interfere with successful immunization. We evaluated the immune responses eli
Autor:
Silvia Perri, Diane E. Griffin, Alexandra Valsamakis, John M. Polo, Fernando P. Polack, Catherine Greer, Teresa Colella, Chien Hsiung Pan, Robert J. Adams, Nitya Nair
Publikováno v:
Proceedings of the National Academy of Sciences. 102:11581-11588
Measles remains a major worldwide problem partly because of difficulties with vaccination of young infants. New vaccine strategies need to be safe and to provide sustained protective immunity. We have developed Sindbis virus replicon particles that e
Autor:
John M. Polo, Indresh K. Srivastava, Derek T. O'Hagan, Michael Vajdy, John J. Donnelly, Manmohan Singh
Publikováno v:
Immunology & Cell Biology. 82:617-627
Almost all vaccinations today are delivered through parenteral routes. Mucosal vaccination offers several benefits over parenteral routes of vaccination, including ease of administration, the possibility of self-administration, elimination of the cha
Autor:
Stephen R. Coates, Qui-Lim Choo, Hyun Chul Song, Takashi Harada, Piero Pileri, Konrad Stadler, Michael Houghton, John M. Polo, Byoung J. Yoo, Catherine Greer, Mi Young Seo, Jang H. Han, Sergio Abrignani, Yasushi Uematsu, Markus Eickmann, Rino Rappuoli
Publikováno v:
Journal of Virology
We have expressed and characterized the severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein in cDNA-transfected mammalian cells. The full-length spike protein (S) was newly synthesized as an endoglycosidase H (endo H)-sensitive gly