Zobrazeno 1 - 10
of 97
pro vyhledávání: '"John M. O'Shea"'
Autor:
John M O'Shea, Ashley K Lemke, Brendan S Nash, Elisabeth P Sonnenburg, Jeffery R Ferguson, Alex J Nyers, Danielle J Riebe
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250840 (2021)
Obsidian, originating from the Rocky Mountains and the West, was an exotic exchange commodity in Eastern North America that was often deposited in elaborate caches and burials associated with Middle Woodland era Hopewell and later complexes. In earli
Externí odkaz:
https://doaj.org/article/21c2c3e16a844444af84dd8fa44514d2
Autor:
George W Cook, Michael G Benton, Wallace Akerley, George F Mayhew, Cynthia Moehlenkamp, Denise Raterman, Daniel L Burgess, William J Rowell, Christine Lambert, Kevin Eng, Jenny Gu, Primo Baybayan, John T Fussell, Heath D Herbold, John M O'Shea, Thomas K Varghese, Lyska L Emerson
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226340 (2020)
Structural variation (SV) is typically defined as variation within the human genome that exceeds 50 base pairs (bp). SV may be copy number neutral or it may involve duplications, deletions, and complex rearrangements. Recent studies have shown SV to
Externí odkaz:
https://doaj.org/article/fe1a2512759f4a7b9faf0b60634d30a7
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Histone deacetylase (HDAC) inhibition has sporadic clinical efficacy in urothelial carcinoma; the genomic basis for clinical response is not known. In two separate phase I clinical trials testing pharmacokinetic aspects of HDAC inhibitors in advanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec4e1e38652dd7a79529d4ba01a40db4
https://doi.org/10.1158/1535-7163.c.6537834.v1
https://doi.org/10.1158/1535-7163.c.6537834.v1
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
GSEA with Hallmark gene sets performed on transcriptional changes in HT1197 cells treated with panobinostat for 48 hours. A. Top 6 downregulated GSEA signatures B. Top 6 upregulated GSEA signatures C. GSEA HT1197 vs UMUC3 ( comparison of transcriptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3dc70c008073ca019badbdc66ba909
https://doi.org/10.1158/1535-7163.22504713
https://doi.org/10.1158/1535-7163.22504713
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Heat map of top 50 genes affected in HT1197 cells when treated with panobinostat at 48 hours log2 gene expression change(HT1197 A-B and C represent control replicates, HT1197 Pano A, B, C represent treated replicates). For the cell lines with replica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a56af42c97fabe3bfcd48fef55e9f8
https://doi.org/10.1158/1535-7163.22504722
https://doi.org/10.1158/1535-7163.22504722
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Individual drug characteristics and doses, maximum plasma levels and protein binding of panobinostat and belinostat in the two phase 1 studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881bc6ec7f2724358ba7b34045aa5295
https://doi.org/10.1158/1535-7163.22504716
https://doi.org/10.1158/1535-7163.22504716
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Study Schema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d03082dfc96e6a789b51e7093790f38
https://doi.org/10.1158/1535-7163.22504728.v1
https://doi.org/10.1158/1535-7163.22504728.v1
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Swimmer Plot to show the best overall response and duration of benefit in seven bladder cancer patients from Table 1 treated with HDAC inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abb7b29048342a29e3e1e00fea1a0e2
https://doi.org/10.1158/1535-7163.22504725.v1
https://doi.org/10.1158/1535-7163.22504725.v1
Autor:
Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Demographic and clinical characteristics of patients treated with belinostat and panobinostat with archived tumor tissue available for study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c198553b1a7942eb81be0ac158350da0
https://doi.org/10.1158/1535-7163.22504719.v1
https://doi.org/10.1158/1535-7163.22504719.v1
Autor:
John M. O’Shea
Publikováno v:
Submerged Prehistory in the Americas ISBN: 9781003371106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b95b7f1552a05746dbd5a0bc1d3f24e
https://doi.org/10.4324/9781003371106-7
https://doi.org/10.4324/9781003371106-7