Zobrazeno 1 - 10 of 92 pro vyhledávání: '"John M. O'Shea"'
1
Akademický článek
Central Oregon obsidian from a submerged early Holocene archaeological site beneath Lake Huron.
Autor: John M O'Shea, Ashley K Lemke, Brendan S Nash, Elisabeth P Sonnenburg, Jeffery R Ferguson, Alex J Nyers, Danielle J Riebe
Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0250840 (2021)
Obsidian, originating from the Rocky Mountains and the West, was an exotic exchange commodity in Eastern North America that was often deposited in elaborate caches and burials associated with Middle Woodland era Hopewell and later complexes. In earli
Externí odkaz: https://doaj.org/article/21c2c3e16a844444af84dd8fa44514d2
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2
Akademický článek
Structural variation and its potential impact on genome instability: Novel discoveries in the EGFR landscape by long-read sequencing.
Autor: George W Cook, Michael G Benton, Wallace Akerley, George F Mayhew, Cynthia Moehlenkamp, Denise Raterman, Daniel L Burgess, William J Rowell, Christine Lambert, Kevin Eng, Jenny Gu, Primo Baybayan, John T Fussell, Heath D Herbold, John M O'Shea, Thomas K Varghese, Lyska L Emerson
Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0226340 (2020)
Structural variation (SV) is typically defined as variation within the human genome that exceeds 50 base pairs (bp). SV may be copy number neutral or it may involve duplications, deletions, and complex rearrangements. Recent studies have shown SV to
Externí odkaz: https://doaj.org/article/fe1a2512759f4a7b9faf0b60634d30a7
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3
Data from Histone Deacetylase Inhibition Has Targeted Clinical Benefit in ARID1A-Mutated Advanced Urothelial Carcinoma
Autor: Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Histone deacetylase (HDAC) inhibition has sporadic clinical efficacy in urothelial carcinoma; the genomic basis for clinical response is not known. In two separate phase I clinical trials testing pharmacokinetic aspects of HDAC inhibitors in advanced
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec4e1e38652dd7a79529d4ba01a40db4
https://doi.org/10.1158/1535-7163.c.6537834.v1
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