Zobrazeno 1 - 10
of 30
pro vyhledávání: '"John M. Ngunjiri"'
Autor:
Amir Ghorbani, John M. Ngunjiri, Gloria Rendon, Christopher B. Brooke, Scott P. Kenney, Chang-Won Lee
Publikováno v:
Viruses, Vol 15, Iss 10, p 2107 (2023)
Influenza A virus (IAV) populations harbor large subpopulations of defective-interfering particles characterized by internally deleted viral genomes. These internally deleted genomes have demonstrated the ability to suppress infectivity and boost inn
Externí odkaz:
https://doaj.org/article/d259cfc757a440fc94edf0b21ef88107
Autor:
Mahesh KC, John M. Ngunjiri, Joonbum Lee, Jinsoo Ahn, Mohamed Elaish, Amir Ghorbani, Michael E.C. Abundo, Kichoon Lee, Chang-Won Lee
Publikováno v:
Poultry Science, Vol 99, Iss 12, Pp 6513-6524 (2020)
Toll-like receptor 3 (TLR3) induces host innate immune response on recognition of viral double-stranded RNA (dsRNA). Although several studies of avian TLR3 have been reported, none of these studies used a gene knockout (KO) model to directly assess i
Externí odkaz:
https://doaj.org/article/9dfccae0cef446528782a333ad927387
Autor:
John M. Ngunjiri, Kara J.M. Taylor, Hana Ji, Michael C. Abundo, Amir Ghorbani, Mahesh KC, Chang-Won Lee
Publikováno v:
PeerJ, Vol 9, p e11806 (2021)
Turkey respiratory and gut microbiota play important roles in promoting health and production performance. Loss of microbiota homeostasis due to pathogen infection can worsen the disease or predispose the bird to infection by other pathogens. While t
Externí odkaz:
https://doaj.org/article/86723a96cfa34c9093d58aca9d8dab5e
Publikováno v:
Avian Diseases. 67
Autor:
Hyesun Jang, Mohamed Elaish, Mahesh Kc, Michael C Abundo, Amir Ghorbani, John M Ngunjiri, Chang-Won Lee
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195285 (2018)
Outbreaks of novel highly pathogenic avian influenza viruses have been reported in poultry species in the United States since 2014. These outbreaks have proven the limitations of biosecurity control programs, and new tools are needed to reinforce the
Externí odkaz:
https://doaj.org/article/fad9201142a743d9a983a6918f3aec58
Autor:
Mohamed Elaish, John M Ngunjiri, Ahmed Ali, Ming Xia, Mahmoud Ibrahim, Hyesun Jang, Jagadish Hiremath, Santosh Dhakal, Yosra A Helmy, Xi Jiang, Gourapura J Renukaradhya, Chang-Won Lee
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171174 (2017)
The current inactivated influenza vaccines provide satisfactory protection against homologous viruses but limited cross-protection against antigenically divergent strains. Consequently, there is a need to develop more broadly protective vaccines. The
Externí odkaz:
https://doaj.org/article/d68f1e00333948a285cfd46c5d100992
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156603 (2016)
Influenza virus mutants that encode C-terminally truncated NS1 proteins (NS1-truncated mutants) are attractive candidates for avian live attenuated influenza vaccine (LAIV) development because they are both attenuated and immunogenic in chickens. We
Externí odkaz:
https://doaj.org/article/ac32d86d2612420b8d2714ef40fc63c3
Autor:
Jinsoo Ahn, Chang-Won Lee, Mohamed Elaish, Joonbum Lee, Amir Ghorbani, John M. Ngunjiri, Michael C. Abundo, Kichoon Lee, Krishnan Mahesh
Publikováno v:
Poultry Science, Vol 99, Iss 12, Pp 6513-6524 (2020)
Poultry Science
Poultry Science
Toll-like receptor 3 (TLR3) induces host innate immune response on recognition of viral double-stranded RNA (dsRNA). Although several studies of avian TLR3 have been reported, none of these studies used a gene knockout (KO) model to directly assess i
Autor:
Chang-Won Lee, Kara J.M. Taylor, John M. Ngunjiri, Hana Ji, Amir Ghorbani, Krishnan Mahesh, Michael C. Abundo
Publikováno v:
PeerJ, Vol 9, p e11806 (2021)
PeerJ
PeerJ
Turkey respiratory and gut microbiota play important roles in promoting health and production performance. Loss of microbiota homeostasis due to pathogen infection can worsen the disease or predispose the bird to infection by other pathogens. While t
Autor:
John M. Ngunjiri, Amir Ghorbani, Michael C. Abundo, Krishnan Mahesh, Kathryn Q. Wilbanks, Chang-Won Lee, Kichoon Lee
Publikováno v:
Avian diseases. 65(3)
Toll-like receptor 3 (TLR3) and melanoma differentiation-associated gene 5 (MDA5) are double-stranded RNA (dsRNA)-recognizing receptors that mediate innate immune responses to virus infection. However, the roles played by these receptors in the patho