Zobrazeno 1 - 10
of 20
pro vyhledávání: '"John M. Millholland"'
Autor:
Rohan Diwanji, Neil A. O'Brien, Jiyoung E. Choi, Beverly Nguyen, Tyler Laszewski, Angelo L. Grauel, Zheng Yan, Xin Xu, Jincheng Wu, David A. Ruddy, Michelle Piquet, Marc R. Pelletier, Alexander Savchenko, LaSalette Charette, Vanessa Rodrik-Outmezguine, Jason Baum, John M. Millholland, Connie C. Wong, Anne-Marie Martin, Glenn Dranoff, Iulian Pruteanu-Malinici, Viviana Cremasco, Catherine Sabatos-Peyton, Pushpa Jayaraman
Publikováno v:
Cancer Immunology Research. :OF1-OF15
High levels of IL1β can result in chronic inflammation, which in turn can promote tumor growth and metastasis. Inhibition of IL1β could therefore be a promising therapeutic option in the treatment of cancer. Here, the effects of IL1β blockade indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2113f881dcef8aa2a9477568837b9bec
https://doi.org/10.1158/2326-6066.cir-22-0290
https://doi.org/10.1158/2326-6066.cir-22-0290
Autor:
Pushpa Jayaraman, Catherine Sabatos-Peyton, Viviana Cremasco, Iulian Pruteanu-Malinici, Glenn Dranoff, Anne-Marie Martin, Connie C. Wong, John M. Millholland, Jason Baum, Vanessa Rodrik-Outmezguine, LaSalette Charette, Alexander Savchenko, Marc R. Pelletier, Michelle Piquet, David A. Ruddy, Jincheng Wu, Xin Xu, Zheng Yan, Angelo L. Grauel, Tyler Laszewski, Beverly Nguyen, Jiyoung E. Choi, Neil A. O'Brien, Rohan Diwanji
Supplementary tables S1-S5 and figures S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a762d6444e9a4cf2897afec74d3f1d1
https://doi.org/10.1158/2326-6066.22812251
https://doi.org/10.1158/2326-6066.22812251
Autor:
Pushpa Jayaraman, Catherine Sabatos-Peyton, Viviana Cremasco, Iulian Pruteanu-Malinici, Glenn Dranoff, Anne-Marie Martin, Connie C. Wong, John M. Millholland, Jason Baum, Vanessa Rodrik-Outmezguine, LaSalette Charette, Alexander Savchenko, Marc R. Pelletier, Michelle Piquet, David A. Ruddy, Jincheng Wu, Xin Xu, Zheng Yan, Angelo L. Grauel, Tyler Laszewski, Beverly Nguyen, Jiyoung E. Choi, Neil A. O'Brien, Rohan Diwanji
High levels of IL1β can result in chronic inflammation, which in turn can promote tumor growth and metastasis. Inhibition of IL1β could therefore be a promising therapeutic option in the treatment of cancer. Here, the effects of IL1β blockade indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3380997b9e0f7a82acb06dfc9d926a
https://doi.org/10.1158/2326-6066.c.6644591
https://doi.org/10.1158/2326-6066.c.6644591
Autor:
Ryan B. Corcoran, Eduard Gasal, Fatima Rangwala, Jan C. Brase, John M. Millholland, Eric Van Cutsem, Filip De Vos, Peter J. O'Dwyer, Rona Yaeger, Josep Tabernero, Michael S. Gordon, Salvatore Siena, Autumn J. McRee, Antoine Hollebecque, Johanna C. Bendell, Takayuki Yoshino, Jan H.M. Schellens, Chloe E. Atreya, Thierry André, Catarina D. Campbell, Yiqun Yang, Gary Middleton
Purpose:The influence of the transcriptional and immunologic context of mutations on therapeutic outcomes with targeted therapy in cancer has not been well defined. BRAF V600E–mutant (BM) colorectal cancer comprises two main transcriptional subtype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2eae5713e450f4d5e8eecaed117b7d
https://doi.org/10.1158/1078-0432.c.6530024
https://doi.org/10.1158/1078-0432.c.6530024
Autor:
Ryan B. Corcoran, Eduard Gasal, Fatima Rangwala, Jan C. Brase, John M. Millholland, Eric Van Cutsem, Filip De Vos, Peter J. O'Dwyer, Rona Yaeger, Josep Tabernero, Michael S. Gordon, Salvatore Siena, Autumn J. McRee, Antoine Hollebecque, Johanna C. Bendell, Takayuki Yoshino, Jan H.M. Schellens, Chloe E. Atreya, Thierry André, Catarina D. Campbell, Yiqun Yang, Gary Middleton
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8a74b6976783c2956bfea8c409cd98
https://doi.org/10.1158/1078-0432.22478705
https://doi.org/10.1158/1078-0432.22478705
Autor:
Lanwei Xu, LiLi Tu, Karen Keeshan, Warren S. Pear, Avinash Bhandoola, Arivazhagan Sambandam, Ivan Maillard, Olga Shestova, Yumi Yashiro-Ohtani, John M. Millholland
Publikováno v:
The Journal of Experimental Medicine
Genetic inactivation of Notch signaling in CD4(-)CD8(-) double-negative (DN) thymocytes was previously shown to impair T cell receptor (TCR) gene rearrangement and to cause a partial block in CD4(+)CD8(+) double-positive (DP) thymocyte development in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a61abf0ab05bc46d2bc137922071734
https://doi.org/10.1084/jem.20061020
https://doi.org/10.1084/jem.20061020
Autor:
Carlos G. Rodriguez, Yue-Ming Li, John W. Tobias, Hong Sai, Andrew P. Weng, Cristina Del Bianco, John M. Millholland, Stephen C. Blacklow, Cathy Shachaf, Dean W. Felsher, Arthur Lau, Michael S. Wolfe, Yumi Yashiro-Ohtani, Carol Wai, Jon C. Aster, Warren S. Pear, Marie Laure Arcangeli
Publikováno v:
Genes & Development. 20:2096-2109
Human acute T-cell lymphoblastic leukemias and lymphomas (T-ALL) are commonly associated with gain-of-function mutations in Notch1 that contribute to T-ALL induction and maintenance. Starting from an expression-profiling screen, we identified c-myc a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d004a1baf785438636d18209f8bd926f
https://doi.org/10.1101/gad.1450406
https://doi.org/10.1101/gad.1450406
Publikováno v:
Progress in Retinal and Eye Research. 24:139-159
We have identified the heavy chain of ferritin as a developmentally regulated nuclear protein of embryonic chicken corneal epithelial cells. The nuclear ferritin is assembled into a supramolecular form that is indistinguishable from the cytoplasmic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfae17db78063540777b175f3122c9b
https://doi.org/10.1016/j.preteyeres.2004.08.004
https://doi.org/10.1016/j.preteyeres.2004.08.004
Autor:
Naomi B. Zak, John M. Fitch, James P. Canner, Cindy X. Cai, Maria Nurminskaya, Christopher J. Talbot, John M. Millholland, James K. Kubilus, Kelly E. Beazley, Thomas F. Linsenmayer
Publikováno v:
Oxidative Stress in Applied Basic Research and Clinical Practice ISBN: 9781493919345
Ultraviolet (UV) light constitutes a major environmental hazard for all exposed tissues of the body. UV light can damage a variety of macromolecules—including alterations to DNA that are potentially carcinogenic. Much of the UV-induced damage to DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44182152ad5654aebf1d1a8b4409563b
https://doi.org/10.1007/978-1-4939-1935-2_3
https://doi.org/10.1007/978-1-4939-1935-2_3
Publikováno v:
Research and Reports in Urology
John M Millholland, Shuqiang Li, Cecilia A Fernandez, Anthony P ShuberPredictive Biosciences Inc, Lexington, MA, USAAbstract: Biological fluid-based noninvasive biomarker assays for monitoring and diagnosing disease are clinically powerful. A major t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8da5116b2be96d81e01ae72ed93bd6f
https://pubmed.ncbi.nlm.nih.gov/24199180
https://pubmed.ncbi.nlm.nih.gov/24199180