Zobrazeno 1 - 10
of 20
pro vyhledávání: '"John M. Heumann"'
Autor:
Charlotte Guyomar, Clément Bousquet, Siou Ku, John M Heumann, Gabriel Guilloux, Natacha Gaillard, Claire Heichette, Laurence Duchesne, Michel O Steinmetz, Romain Gibeaux, Denis Chrétien
Publikováno v:
eLife, Vol 11 (2022)
Microtubules are tubes of about 25 nm in diameter that are critically involved in a variety of cellular functions, including motility, compartmentalization, and division. They are considered as pseudo-helical polymers whose constituent αβ-tubulin h
Externí odkaz:
https://doaj.org/article/9c51fb0f95b84d70af1fa4796c5053a7
Autor:
Charlotte Guyomar, Clément Bousquet, Siou Ku, John M Heumann, Gabriel Guilloux, Natacha Gaillard, Claire Heichette, Laurence Duchesne, Michel O Steinmetz, Romain Gibeaux, Denis Chrétien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3a8deed3fd0a50b8f8e23accf083d3a
https://doi.org/10.7554/elife.83021.sa2
https://doi.org/10.7554/elife.83021.sa2
Autor:
Laurence Duchesne, Romain Gibeaux, Gaillard N, Michel O. Steinmetz, Siou Ku, Gabriel Guilloux, John M. Heumann, Claire Heichette, Denis Chrétien, Charlotte Guyomar, Bousquet C
Microtubules are tubes of about 25 nm in diameter that are critically involved in a variety of cellular functions including motility, compartmentalization, and division. They are considered as pseudo-helical polymers whose constituent αβ-tubulin he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2613d0f7170831631be62333bfd9ddf
https://doi.org/10.1101/2021.07.14.452321
https://doi.org/10.1101/2021.07.14.452321
Autor:
Nicholas K. Sauter, Aaron S. Brewster, Grant J. Jensen, Petrus H. Zwart, John M. Heumann, Qing Yao, Ariana Peck
Publikováno v:
Acta crystallographica. Section D, Structural biology, vol 77, iss Pt 5
Acta Crystallographica. Section D, Structural Biology
Acta Crystallographica. Section D, Structural Biology
A data-processing pipeline to solve structures from tomograms of protein nanocrystals is presented and validated using simulated crystals. The robustness of this workflow to radiation damage is assessed to investigate optimal data-collection strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7602af84b4d5d56b47b4db6743b64ea4
https://escholarship.org/uc/item/2426j1hs
https://escholarship.org/uc/item/2426j1hs
Autor:
Koustav Maity, John M. Heumann, Aaron P. McGrath, Noah J. Kopcho, Po-Kai Hsu, Chang-Wook Lee, James H. Mapes, Denisse Garza, Srinivasan Krishnan, Garry P. Morgan, Kevin J. Hendargo, Thomas Klose, Steven D. Rees, Arturo Medrano-Soto, Milton H. Saier, Miguel Piñeros, Elizabeth A. Komives, Julian I. Schroeder, Geoffrey Chang, Michael H. B. Stowell
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 28
Sensing and responding to environmental water deficiency and osmotic stresses are essential for the growth, development, and survival of plants. Recently, an osmolality-sensing ion channel called OSCA1 was discovered that functions in sensing hyperos
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43783 (2012)
Giardia lamblia is a flagellated, unicellular parasite of mammals infecting over one billion people worldwide. Giardia's two-stage life cycle includes a motile trophozoite stage that colonizes the host small intestine and an infectious cyst form that
Externí odkaz:
https://doaj.org/article/63939e4088704ea99b6bcfd493a31ec1
Autor:
Pradeep K. Luther, Michael K. Reedy, Kuan Wang, John M. Heumann, Thomas Burgoyne, Jun Liu, Edward P. Morris, Carlo Knupp, Kenneth A. Taylor
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(31)
Striated muscle enables movement in all animals by the contraction of myriads of sarcomeres joined end to end by the Z-bands. The contraction is due to tension generated in each sarcomere between overlapping arrays of actin and myosin filaments. At t
Autor:
Srinivasan Krishnan, Milton H. Saier, Noah J. Kopcho, Aaron P. McGrath, Geoffrey Chang, John M. Heumann, Elizabeth A. Komives, Arturo Medrano-Soto, Julian I. Schroeder, Miguel A. Piñeros, Po-Kai Hsu, Michael H. B. Stowell, Koustav Maity
Publikováno v:
Biophysical Journal. 118:211a
Autor:
Davide, Zabeo, John M, Heumann, Cindi L, Schwartz, Azusa, Suzuki-Shinjo, Garry, Morgan, Per O, Widlund, Johanna L, Höög
Publikováno v:
Scientific Reports
Eukaryotic flagella are complex cellular extensions involved in many human diseases gathered under the term ciliopathies. Currently, detailed insights on flagellar structure come mostly from studies on protists. Here, cryo-electron tomography (cryo-E
Autor:
Michael H. B. Stowell, Keeshia Wang, Tamara Basta, Jonas Lee, John M. Heumann, Yung-Cheng Lee, Douglas C. Rees, Mary K. Morphew, Hsin-Jui Wu, Jeffrey Y. Lai, Nilanjan Ghosh
Publikováno v:
Proceedings of the National Academy of Sciences. 111:670-674
We demonstrate that membrane proteins and phospholipids can self-assemble into polyhedral arrangements suitable for structural analysis. Using the Escherichia coli mechanosensitive channel of small conductance (MscS) as a model protein, we prepared m