Templated Self-Assembly of Dynamic Peptide Nucleic Acids

Autor: Luke J. Leman, Yasuyuki Ura, M. Reza Ghadiri, John M. Beierle

Publikováno v: Biochemistry. 57(1)

Template-directed macromolecule synthesis is a hallmark of living systems. Inspired by this natural process, several fundamentally novel mechanisms for template-directed assembly of nucleic acid analogues have been developed. Although these approache

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c089e4d2abc324f6a175e1175a21e74c
https://pubmed.ncbi.nlm.nih.gov/28832127

An Improved Method for Site-Specific End Modification of Zeolite L for the Formation of Zeolite L and Gold Nanoparticle Self-Assembled Structures

Autor: Robby Roswanda, Wesley R. Browne, Ben L. Feringa, Petra M. Erne, Anthony C. Coleman, John M. Beierle

Publikováno v: Particle & Particle Systems Characterization, 30(3), 273-279. WILEY-V C H VERLAG GMBH
Particle & Particle Systems Characterization

The ability to site-selectively modify micro- and nanosized particles has allowed for directed self-assembly in two and three dimensions. Site-selective modification of particles can be a complicated task requiring the pre-organization of particles o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75855af7d4b9c67db9bc45998a1d517b
https://doi.org/10.1002/ppsc.201200077

Conformationally Homogeneous Heterocyclic Pseudotetrapeptides as Three‐Dimensional Scaffolds for Rational Drug Design: Receptor‐Selective Somatostatin Analogues

Autor: John M. Beierle, W.undefinedSeth Horne, JanundefinedH. vanundefinedMaarseveen, Beatrice Waser, JeanundefinedClaude Reubi, M.undefinedReza Ghadiri

Publikováno v: Angewandte Chemie. 121:4819-4823

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74b28dd23bac0406a1513139fb04a006
https://doi.org/10.1002/ange.200805901

Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: Receptor-selective somatostatin analogues

Autor: John M. Beierle, Jean Claude Reubi, Jan H. van Maarseveen, W. Seth Horne, Beatrice Waser, M. Reza Ghadiri

Publikováno v: Angewandte Chemie, International Edition, 48(26), 4725-4729. John Wiley and Sons Ltd

Many protein-protein interactions are mediated through the recognition of β-turn secondary structures. Consequently, small-molecule β-turn mimetics are invaluable as probes for assessing bioactive ligand conformations, establishing pharmacophoric r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824c44c717a48fc3fb9ff6380e36890c
https://hdl.handle.net/11245/1.312479

Epitope discovery for a synthetic polymer nanoparticle: A new strategy for developing a peptide tag

Autor: Linda F. Epstein, Keiichi Yoshimatsu, Yu Hoshino, John M. Beierle, Paul E. Rose, Kenneth J. Shea, Les P. Miranda, Philip Tagari, Tomohiko Yamazaki, Yusuke Yonamine

Publikováno v: Yoshimatsu, K; Yamazaki, T; Hoshino, Y; Rose, PE; Epstein, LF; Miranda, LP; et al.(2014). Epitope discovery for a synthetic polymer nanoparticle: A new strategy for developing a peptide tag. Journal of the American Chemical Society, 136(4), 1194-1197. doi: 10.1021/ja410817p. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9v59x55n
Journal of the American Chemical Society
Journal of the American Chemical Society, vol 136, iss 4

We describe a novel epitope discovery strategy for creating an affinity agent/peptide tag pair. A synthetic polymer nanoparticle (NP) was used as the "bait" to catch an affinity peptide tag. Biotinylated peptide tag candidates of varied sequence and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35d2dc9225546b043ece33982d85055
http://www.escholarship.org/uc/item/9v59x55n