Zobrazeno 1 - 10
of 11
pro vyhledávání: '"John M. Aversa"'
Autor:
Allen C. Steere, Luke S. Oh, Sheila L. Arvikar, Robert B. Lochhead, Benton E. Heyworth, David Ordoñez, John M. Aversa, Ruslan I. Sadreyev, Klemen Strle
Publikováno v:
Cellular Microbiology. 21
Lyme arthritis (LA), a late disease manifestation of Borrelia burgdorferi infection, usually resolves with antibiotic therapy. However, some patients develop proliferative synovitis lasting months to several years after spirochetal killing, called po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91055453eff8c71512c3508ae6b1ba46
https://doi.org/10.1111/cmi.12992
https://doi.org/10.1111/cmi.12992
Autor:
John M. Aversa, Allen C. Steere, Klemen Strle, Sheila L. Arvikar, Ruslan I. Sadreyev, Robert B. Lochhead
In most patients with Lyme arthritis (LA), antibiotic therapy results in Borrelia burgdorferi pathogen elimination, tissue repair, and return to homeostasis. However, despite spirochetal killing, some patients develop proliferative synovitis, charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101015f21e1c91fb09a6d1a415416841
https://europepmc.org/articles/PMC6724218/
https://europepmc.org/articles/PMC6724218/
Autor:
Robert B. Lochhead, Klemen Strle, Allen C. Steere, Nancy D. Kim, John M. Aversa, Sheila L. Arvikar, Minna J. Kohler
Objective Lyme arthritis (LA) is caused by infection with Borrelia burgdorferi and usually resolves following spirochetal killing with antibiotics. However, in some patients, arthritis persists after antibiotic therapy. To provide insights into under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e36fb80e9b0ea063dbe6beee1d99a89
https://europepmc.org/articles/PMC5406251/
https://europepmc.org/articles/PMC5406251/
Autor:
Elise E. Drouin, Diana Londoño, Klemen Strle, John M. Aversa, Diego Cadavid, Gail McHugh, Allen C. Steere
Publikováno v:
Arthritis & Rheumatology. 66:2124-2133
Lyme disease in the northeastern United States is caused by the tick-transmitted spirochete, Borrelia burgdorferi (1). The most common late manifestation of the infection is Lyme arthritis, which often affects one or both knees (2). Most patients can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14920e8bec4bd6afe44ce8ad27bc610
https://doi.org/10.1002/art.38618
https://doi.org/10.1002/art.38618
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 85:1488-1496
Background: Pain in the retrocalcaneal space can be incapacitating. Patients who do not respond to nonoperative treatment may seek a surgical solution. The first purpose of this paper was to describe and evaluate the efficacy of a minimally invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ecda6e91e7e8667057ef495630a170
https://doi.org/10.2106/00004623-200308000-00009
https://doi.org/10.2106/00004623-200308000-00009
Publikováno v:
Infection and Immunity. 69:1774-1780
The expression of adhesion molecules in synovium in patients with Lyme arthritis is surely critical in the control ofBorrelia burgdorferiinfection but may also have pathologic consequences. For example, molecular mimicry between a dominant T-cell epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c08bba45ba6e62e65a9cd20bd38d8c
https://doi.org/10.1128/iai.69.3.1774-1780.2001
https://doi.org/10.1128/iai.69.3.1774-1780.2001
Autor:
Allen C. Steere, Bradley J. Bloom, Jenifer Coburn, David Carlson, Jesus Hernandez, John M. Aversa
Publikováno v:
Arthritis & Rheumatism. 42:2705-2709
Objective. To determine whether Borrelia burgdorferi DNA may be detected in synovial tissue from patients with Lyme arthritis who have persistent synovial inflammation after antibiotic treatment. Methods. Synovial specimens obtained at synovectomy fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dcd8522660a10907f07a5bd40e5bd25
https://doi.org/10.1002/1529-0131(199912)42:12<2705::aid-anr29>3.0.co
https://doi.org/10.1002/1529-0131(199912)42:12<2705::aid-anr29>3.0.co
Publikováno v:
The Journal of Infectious Diseases. 178:1198-1201
Borrelia burgdorferi, the agent of Lyme disease, selectively expresses genes in the arthropod vector and mammalian host. Specific B. burgdorferi gene expression during human infection was examined in tissue specimens, using RNA ‐ polymerase chain r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedd36116ea14d7ee7c77cff634914f7
https://doi.org/10.1086/515684
https://doi.org/10.1086/515684
Autor:
Leonard H. Sigal, Sheldon M. Cooper, Harsh Trivedi, Karen Roessner, Lakshmi K. Gaur, Diantha B. Howard, John M. Aversa, Ralph C. Budd
Publikováno v:
Infection and Immunity. 66:1092-1099
A common concern with many autoimmune diseases of unknown etiology is the extent to which tissue T-lymphocyte infiltrates, versus a nonspecific infiltrate, reflect a response to the causative agent. Lyme arthritis can histologically resemble rheumato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd8fe70b6b1295fe3369cb24eb5be70
https://doi.org/10.1128/iai.66.3.1092-1099.1998
https://doi.org/10.1128/iai.66.3.1092-1099.1998
Publikováno v:
Arthritis & Rheumatism. 34:1056-1060
Of 20 patients who underwent arthroscopic synovectomy for refractory chronic Lyme arthritis of the knee, 16 (80%) had resolution of joint inflammation during the first month after surgery or soon thereafter, and they have remained well during the 3-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63c12d286e7c650f22428278a00fcb3
https://doi.org/10.1002/art.1780340817
https://doi.org/10.1002/art.1780340817