Zobrazeno 1 - 10
of 79
pro vyhledávání: '"John M. Amatruda"'
Autor:
Ronald B. Langdon, Gregory T. Golm, Juan Camilo Arjona Ferreira, John M. Amatruda, Julie Hill, Yu Chen, Adrian S. Dobs, Lorraine Duran, Pablo Aschner, Keith D. Kaufman, D. E. Williams-Herman, Barry J. Goldstein, Edward S. Horton, Guillermo E. Umpierrez
Publikováno v:
Journal of Diabetes. 5:68-79
Background: New therapeutic approaches are needed to improve glycemic control in patients with type 2 diabetes (T2D), a progressive disorder that often requires combination therapy. The present study assessed the efficacy and safety of sitagliptin as
Autor:
Naoko Tajima, Kenji Nonaka, Mikio Nishii, John M. Amatruda, Juan Camilo Arjona Ferreira, Takashi Kadowaki, Atsunori Kashiwagi, Tadaaki Taniguchi
Publikováno v:
Journal of Diabetes Investigation. 2:381-390
Aims/Introduction: Patients with type 2 diabetes mellitus often require treatment with more than one oral antihyperglycemic agent to achieve their glycemic goal. The present study was carried out to assess the efficacy and safety of sitagliptin as ad
Autor:
Gregory T. Golm, G. R. Shockey, R. Teng, John M. Amatruda, Keith D. Kaufman, Kun Ho Yoon, Helmut O. Steinberg, Alan G. Meehan, P. Thakkar, D. E. Williams-Herman
Publikováno v:
International Journal of Clinical Practice. 65:154-164
Summary Aim/hypothesis: To assess the safety and efficacy of initial combination therapy with sitagliptin and pioglitazone compared with pioglitazone monotherapy in drug-naive patients with type 2 diabetes. Methods: A total of 520 patients were rando
Autor:
Keith D. Kaufman, Ngozi Erondu, Amy O. Johnson-Levonas, Søren Toubro, Shailaja Suryawanshi, Menghui Chen, Deborah R. Shapiro, John M. Amatruda, Ira Gantz, Wendy L. Carofano, Thomas A. Wadden, Ken Fujioka, Steven B. Heymsfield
Publikováno v:
Obesity. 18:2301-2310
Improving the maintenance of weight loss remains a critical challenge for obesity researchers. The present 1-year, randomized, placebo-controlled trial evaluated the safety and efficacy of weight maintenance counseling combined with either placebo or
Autor:
S. B. Heymsfield, Ken Fujioka, Priscilla Hollander, Deborah R. Shapiro, John M. Amatruda, M. Z. Chou, M. S. Kipnes, Yue Shentu, Ngozi Erondu, Ira Gantz, Shailaja Suryawanshi, Keith D. Kaufman, Amy O. Johnson-Levonas, Kaifeng Lu, Thomas Seck
Publikováno v:
Diabetes, Obesity and Metabolism. 12:517-531
Aim: To evaluate the efficacy and safety of taranabant in overweight and obese patients with type 2 diabetes mellitus (T2DM). Methods: This was a multicenter, double-blind, randomized, placebo-controlled study in overweight and obese patients with T2
Autor:
Keith D. Kaufman, Jeremy Johnson, E. Luo, John M. Amatruda, Michael J. Davies, Rujun Teng, D. E. Williams-Herman, Barry J. Goldstein
Publikováno v:
Current Medical Research and Opinion. 25:569-583
To assess the 54-week efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes and inadequate glycemic control (HbA(1c) 7.5-11%) on diet and exercise.This was multinational study conducted at
Autor:
Wenying Yang, Peter P. Stein, Liliane Noble, Viswanathan Mohan, John M. Amatruda, Keith D. Kaufman, Lei Xu, Ronald B. Langdon, Ho-Young Son
Publikováno v:
Diabetes Research and Clinical Practice. 83:106-116
The efficacy and safety of sitagliptin as monotherapy were evaluated in Chinese, Indian, and Korean patients with type 2 diabetes inadequately controlled by diet and exercise. In a randomized, placebo-controlled, double-blind, 18-week trial, 530 pati
Effect of NPY5R Antagonist MK-0557 on Weight Regain after Very-low-calorie Diet-induced Weight Loss*
Autor:
Bret J. Musser, Arnaud Basdevant, Steven B. Heymsfield, Allison Martin Nguyen, John M. Amatruda, Ngozi Erondu, Harold Bays, Ira Gantz, Keith D. Kaufman, Patrick M. O'Neil, Thomas A. Wadden, George A. Bray
Publikováno v:
Obesity. 15:895-905
Objective: To evaluate whether MK-0557, a highly selective, orally administered neuropeptide Y Y5 receptor antagonist, could limit weight regain after very-low-calorie diet (VLCD)-induced weight loss. Research Methods and Procedures: We enrolled 502
Publikováno v:
Metabolism. 44:1413-1416
Obesity is a well-known health risk factor. Several studies have demonstrated that upper-body fat distribution plays a major role in the association between increased adiposity and metabolic disorders. The present study was undertaken to evaluate cha
Autor:
John M. Amatruda, Silvio E. Inzucchi
Publikováno v:
Diabetes Care. 26:1309-1311
“… with fat diabetes begins. From fat diabetics die, formerly of coma and recently of … arteriosclerosis.” Three-quarters of a century ago, Dr. Elliot Joslin succinctly summarized two of the lethal consequences of diabetes before (ketoacidosi