Výsledky vyhledávání - "John M. A. Northover"

Life after PROSPER. What do people do for external rectal prolapse?

Autor: A Senapati, S. R. Brown, C. K. Gunner, John M. A. Northover

Publikováno v: Colorectal Disease. 18:811-814

Aim A questionnaire completed by members of the ACPGBI in 1997 was a precursor to the PROSPER trial. It showed a significant variation in favoured practice for the surgical treatment of external rectal prolapse. We repeated the same questionnaire to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e63e64694aa1ef9b4d5e9b9a2253ba9
https://doi.org/10.1111/codi.13255

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Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I)

Autor: Helen Meadows, Rob Glynne-Jones, Roger D James, S Wan, David Sebag-Montefiore, John M. A. Northover, Mark Jitlal, Jonathan A. Ledermann

Publikováno v: British Journal of Cancer

Background: The first UKCCCR Anal Cancer Trial (1996) demonstrated the benefit of chemoradiation over radiotherapy (RT) alone for treating epidermoid anal cancer, and it became the standard treatment. Patients in this trial have now been followed up

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83968c7dfa71af520dcf577185327bdc
http://europepmc.org/articles/PMC2853094

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Can histopathologic assessment of circumferential margin after preoperative pelvic chemoradiotherapy for T3-T4 rectal cancer predict for 3-year disease-free survival?

Autor: Alastair Windsor, Jeremy I Livingstone, Mark Harrison, Richard Ashford, Suzannah Mawdsley, Andreas Makris, Peter MacDonald, John M. A. Northover, Richard A. Harrison, Richard Novell, John Meyrick-Thomas, Marina Wallace, Paul Richman, Melanie Osborne, Rob Glynne-Jones, Juliet Grainger, Ian C. Mitchell

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 63:745-752

Purpose: This study set out to determine the impact of a positive circumferential resection margin (CRM) (R1-R2) and pathologic downstaging on local recurrence and survival in patients with borderline resectable or unresectable rectal adenocarcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f7ac97f29f0e29ded641c399f369a9
https://doi.org/10.1016/j.ijrobp.2005.03.003

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Can pathological complete response in the primary tumour following pre-operative pelvic chemoradiotherapy for T3–T4 rectal cancer predict for sterilisation of pelvic lymph nodes, a low risk of local recurrence and the appropriateness of local excision?

Autor: Rob Glynne-Jones, Robin K. S. Phillips, Matthew T. Harrison, Richard Ashford, Roger A Harrison, A. Windsor, I.C. Mitchell, J. Meyrick Thomas, P.J. Mcdonald, Andreas Makris, J. Grainger, Marina Wallace, Paul Richman, J.R. Novell, John M. A. Northover, R. Hughes, Jeremy I Livingstone

Publikováno v: International Journal of Colorectal Disease. 21:11-17

Local excision is considered inappropriate treatment for T3–T4 rectal adenocarcinomas, as it cannot provide prognostic information regarding lymph node involvement and has a high risk of pelvic recurrence. Preoperative chemoradiation (CRT) studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479df7ea0d3a65414c503c70ffa7b793
https://doi.org/10.1007/s00384-005-0749-y

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Use of a modified Delphi approach to develop research priorities for the association of coloproctology of Great Britain and Ireland

Autor: Bruce George, J. Wheeler, Nicola S Fearnhead, Andrew Cook, Laura Magill, Azmina Verjee, I. Geh, John M. A. Northover, J. Tiernan

Publikováno v: Colorectal Disease

AIM:The modified Delphi approach is an established method for reaching a consensus opinion among a group of experts in a particular field. We have used this technique to survey the entire membership of the Association of Coloproctology of Great Brita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c1382bf89e55def1585a5d4946c1a1
https://pubmed.ncbi.nlm.nih.gov/25284641

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Surgery for colorectal cancer in elderly patients: a systematic review

Autor: Roger B. Buchanan, Ian S. Fentiman, Chris Baughan, John M. A. Northover, Margot Gosney, Stephen L. George, Peter Simmonds, C.E. Davis, Chris Williams, L Best

Publikováno v: The Lancet. 356:968-974

Summary Background The effectiveness of surgery for colorectal cancer depends on it being carried out safely, which allows most patients to return to productive lives, with an improved postoperative life expectancy, or at least one that is not dimini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d36b23011b671cbc9dfdc7be7048853c
https://doi.org/10.1016/s0140-6736(00)02713-6

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Evaluation of surgery for perianal Crohn's fistulas

Autor: John M. A. Northover, Humphrey J. Scott

Publikováno v: Diseases of the Colon & Rectum. 39:1039-1043

PURPOSE: This study was designed to evaluate the operative treatments performed on patients with perianal Crohn's disease at a tertiary referral colorectal university hospital and to determine the efficacy of management by assessing patient satisfact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0beacb42fa0e9eee42c21a0eb7ccb4c1
https://doi.org/10.1007/bf02054696

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'Mind the gap'--the impact of variations in the duration of the treatment gap and overall treatment time in the first UK Anal Cancer Trial (ACT I)

Autor: Alec McDonald, Mark Jitlal, John M. A. Northover, David Sebag-Montefiore, Simon Gollins, Rob Glynne-Jones, Roger D James, Helen Meadows, Richard Adams

Publikováno v: International journal of radiation oncology, biology, physics. 81(5)

Purpose: The United Kingdom Coordinating Committee on Cancer Research anal cancer trial demonstrated the benefit of combined modality treatment (CMT) using radiotherapy (RT), infusional 5-fluorouracil, and mitomycin C over RT alone. The present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c9c00dfda5ec4a7974d330cb86f592
https://pubmed.ncbi.nlm.nih.gov/20934265

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Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial

Autor: Wendy S, Atkin, Rob, Edwards, Ines, Kralj-Hans, Kate, Wooldrage, Andrew R, Hart, John M A, Northover, D Max, Parkin, Jane, Wardle, Stephen W, Duffy, Jack, Cuzick, S, Fitzpatrick

Publikováno v: Lancet (London, England). 375(9726)

Summary Background Colorectal cancer is the third most common cancer worldwide and has a high mortality rate. We tested the hypothesis that only one flexible sigmoidoscopy screening between 55 and 64 years of age can substantially reduce colorectal c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f8935e10834a43db23d6507687e9e6
https://pubmed.ncbi.nlm.nih.gov/21043012

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Does the timing of comorbidity affect colorectal cancer survival? A population based study

Autor: Evelyn M. I. Williams, Lorraine Shack, Michel P Coleman, Bernard Rachet, John M A Northover

Publikováno v: Postgraduate medical journal. 86(1012)

Objectives Comorbid conditions in colorectal cancer patients can influence both clinical eligibility for treatment and survival. We aimed to evaluate the effect of comorbidity on 1 year survival from colorectal cancer, and to assess whether this effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd2bf233db3bb42014c7f8dfde37a5c
https://pubmed.ncbi.nlm.nih.gov/20145054

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