Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John M Urban"'
Publikováno v:
eLife, Vol 12 (2023)
Highly potent animal stem cells either self renew or launch complex differentiation programs, using mechanisms that are only partly understood. Drosophila female germline stem cells (GSCs) perpetuate without change over evolutionary time and generate
Externí odkaz:
https://doaj.org/article/9157b37e1c454bf6bae501445ff206fc
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189772 (2017)
Gaining new insights into gene regulation involves an in-depth understanding of protein-protein interactions on chromatin. A powerful model for studying mechanisms of gene regulation is dosage compensation, a process that targets the X-chromosome to
Externí odkaz:
https://doaj.org/article/7f39831fb1014d0bb418867a6e4e50ba
Autor:
Robert B. Baird, John M. Urban, Andrew J. Mongue, Kamil S. Jaron, Christina N. Hodson, Malte Grewoldt, Simon H. Martin, Laura Ross
Publikováno v:
Baird, R B, Urban, J M, Mongue, A J, Jaron, K S, Hodson, C N, Grewoldt, M, Martin, S H & Ross, L 2023, ' Recent evolution of a maternally-acting sex-determining supergene in a fly with single-sex broods ', Molecular Biology and Evolution . https://doi.org/10.1093/molbev/msad148
Baird, R B, Urban, J M, Mongue, A J, Jaron, K S, Hodson, C N, Grewoldt, M, Martin, S H & Ross, L 2023, ' Recent evolution of a maternally-acting sex-determining supergene in a fly with single-sex broods ', Molecular Biology and Evolution, vol. 40, no. 7, msad148 . https://doi.org/10.1093/molbev/msad148
Baird, R B, Urban, J M, Mongue, A J, Jaron, K S, Hodson, C N, Grewoldt, M, Martin, S H & Ross, L 2023, ' Recent evolution of a maternally-acting sex-determining supergene in a fly with single-sex broods ', Molecular Biology and Evolution, vol. 40, no. 7, msad148 . https://doi.org/10.1093/molbev/msad148
Sex determination is a key developmental process, yet it is remarkably variable across the tree of life. The dipteran family Sciaridae exhibits one of the most unusual sex determination systems in which mothers control offspring sex through selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5ec5232dc5b686936574e96ccddd5a
https://pure.au.dk/portal/da/publications/recent-evolution-of-a-maternallyacting-sexdetermining-supergene-in-a-fly-with-singlesex-broods(da7a2a0a-d4fb-40c5-b6d6-585998264a41).html
https://pure.au.dk/portal/da/publications/recent-evolution-of-a-maternallyacting-sexdetermining-supergene-in-a-fly-with-singlesex-broods(da7a2a0a-d4fb-40c5-b6d6-585998264a41).html
BackgroundThe lower dipteran fungus gnat,Bradysia(Sciara)coprophila, has unusual chromosome biology. Chromosome imprinting was first discovered in this system. All paternal chromosomes are eliminated during spermatogenesis whereas both maternal X sis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7c6b9c7cc9a478bd23753016527346
https://doi.org/10.1101/2022.11.03.515061
https://doi.org/10.1101/2022.11.03.515061
Autor:
Jack R. Bateman, Julia Borden, Alexia Brown, Jaison Jain, Jacob E. Bliss, Bethany J. Thach, Kodie R. Garza, Susan A. Gerbi, John M. Urban
Robust DNA damage prevention and repair strategies are crucial to faithful reproduction and inheritance of the genetic material. Although many molecular pathways that respond to DNA damage are well conserved through evolution, the quality and effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef9c3ae79b81eb825f7bdf3ea12d93bd
https://doi.org/10.1101/2021.10.28.466123
https://doi.org/10.1101/2021.10.28.466123
Autor:
Jacob E. Bliss, Susan A. Gerbi, Nanyan Lu, John M. Urban, Reza Mazloom, C Michelle Coleman, Michael S. Foulk, Susan J. Brown, Allan C. Spradling
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-23 (2021)
BMC Genomics
BMC Genomics
Background The lower Dipteran fungus fly, Sciara coprophila, has many unique biological features that challenge the rule of genome DNA constancy. For example, Sciara undergoes paternal chromosome elimination and maternal X chromosome nondisjunction d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a18119d638e1fcd55b8bb37f4ccf6a
https://doi.org/10.1186/s12864-021-07926-2
https://doi.org/10.1186/s12864-021-07926-2
Autor:
Susan A. Gerbi, Nanyan Lu, John M. Urban, Jacob E. Bliss, C. M. Coleman, Michael S. Foulk, Reza Mazloom, Susan J. Brown, Allan C. Spradling
The lower Dipteran fungus fly,Sciara coprophila, has many unique biological features. For example,Sciaraundergoes paternal chromosome elimination and maternal X chromosome nondisjunction during spermatogenesis, paternal X elimination during embryogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c07ceb9cd753307997dd7b650019d4
https://doi.org/10.1101/2020.02.24.963009
https://doi.org/10.1101/2020.02.24.963009
Publikováno v:
Foulk, M S, Urban, J M, Casella, C & Gerbi, S A 2015, ' Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins ', Genome Research, vol. 25, no. 5, pp. 725-735 . https://doi.org/10.1101/gr.183848.114
Nascent strand sequencing (NS-seq) is used to discover DNA replication origins genome-wide, allowing identification of features for their specification. NS-seq depends on the ability of lambda exonuclease (λ-exo) to efficiently digest parental DNA w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b75cf9807facf62fc24ddbace600acb
https://doi.org/10.1101/gr.183848.114
https://doi.org/10.1101/gr.183848.114
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189772 (2017)
PLoS ONE, Vol 12, Iss 12, p e0189772 (2017)
Gaining new insights into gene regulation involves an in-depth understanding of protein-protein interactions on chromatin. A powerful model for studying mechanisms of gene regulation is dosage compensation, a process that targets the X-chromosome to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f7edf289b42d2a7e73e26dde6f933a
https://pubmed.ncbi.nlm.nih.gov/29281702
https://pubmed.ncbi.nlm.nih.gov/29281702
Autor:
Camilla L.C. Ip, Matthew Loose, John R. Tyson, Mariateresa de Cesare, Bonnie L. Brown, Miten Jain, Richard M. Leggett, David A. Eccles, Vadim Zalunin, John M. Urban, Paolo Piazza, Rory J. Bowden, Benedict Paten, Solomon Mwaigwisya, Elizabeth M. Batty, Jared T. Simpson, Terrance P. Snutch, Ewan Birney, David Buck, Sara Goodwin, Hans J. Jansen, Justin O'Grady, Hugh E. Olsen, MinION Analysis and Reference Consortium
Publikováno v:
F1000Research, Vol 4 (2015)
The advent of a miniaturized DNA sequencing device with a high-throughput contextual sequencing capability embodies the next generation of large scale sequencing tools. The MinION™ Access Programme (MAP) was initiated by Oxford Nanopore Technologie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::59eee50796b9b126d41bea969d3d1be0
http://f1000research.com/articles/4-1075/v1
http://f1000research.com/articles/4-1075/v1