Zobrazeno 1 - 3
of 3
pro vyhledávání: '"John M Patino"'
Autor:
Julen Oyarzabal, Robert Arnes-Benito, Leticia Colyn, Jose J.G. Marin, Jose M Herranz, Maite G. Fernandez-Barrena, María J. Iraburu, Maria Francesconi, Gloria Alvarez-Sola, Meritxell Huch, Leonard J Nelson, Francisco Javier Cubero, Matías A. Avila, Altaf A. Dar, Jesus M. Banales, Iker Uriarte, Mikel Ruiz de Gauna, Simone Carotti, Jesús Urman, Sergio Morini, María L. Martínez-Chantar, Chaobo Chen, Marina Bárcena-Varela, Eva Santamaría, Andrea Casadei-Gardini, Christian Trautwein, Patricia Aspichueta, Alvaro Santos-Laso, Carmen Berasain, Felipe Prosper, Bruno Sangro, John M Patino, Matteo Canale, Mehdi Nosrati, María Arechederra, M. Ujue Latasa
Publikováno v:
Hepatology. 73:2380-2396
Background and aims Cholangiocarcinoma (CCA) is a devastating disease often detected at advanced stages when surgery cannot be performed. Conventional and targeted systemic therapies perform poorly, and therefore effective drugs are urgently needed.
Autor:
Altaf A. Dar, Vladimir Bezrookove, Mehdi Nosrati, Ryan Ice, John M. Patino, Edith M. Vaquero, Brian Parrett, Stanley P. Leong, Kevin B. Kim, Robert J. Debs, Liliana Soroceanu, James R. Miller, Pierre-Yves Desprez, James E. Cleaver, Nathan Salomonis, Sean McAllister, Mohammed Kashani-Sabet
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 34
Therapy of BRAF -mutant melanoma with selective inhibitors of BRAF (BRAFi) and MEK (MEKi) represents a major clinical advance but acquired resistance to therapy has emerged as a key obstacle. To date, no clinical approaches successfully resensitize t
Autor:
Liliana Soroceanu, Altaf A. Dar, Pierre-Yves Desprez, Robert W. Osorio, John M Patino, Mohammed Kashani-Sabet, Mehdi Nosrati, Ari David Baron, Vladimir Bezrookove, Sean D. McAllister
Publikováno v:
Cancers
Volume 13
Issue 17
Cancers, Vol 13, Iss 4405, p 4405 (2021)
Volume 13
Issue 17
Cancers, Vol 13, Iss 4405, p 4405 (2021)
Simple Summary Cholangiocarcinoma (CCA) is a rare and highly aggressive tumor with limited therapeutic options, thus underscoring the need to develop novel therapeutic approaches. We analyzed a publicly available CCA patient database to identify muta