Zobrazeno 1 - 10
of 90
pro vyhledávání: '"John M Ong'echa"'
Autor:
Sean V Connelly, Nicholas F Brazeau, Mwinyi Msellem, Billy E Ngasala, Ozkan Aydemir, Varun Goel, Karamoko Niaré, David J Giesbrecht, Zachary R Popkin-Hall, Chris Hennelly, Zackary Park, Ann M Moormann, John M Ong'echa, Robert Verity, Safia Mohammed, Shija J Shija, Lwidiko E Mhamilawa, Ulrika Morris, Andreas Mårtensson, Jessica T Lin, Anders Björkman, Jonathan J Juliano, Jeffrey A Bailey
Publikováno v:
eLife, Vol 12 (2024)
Background: The Zanzibar archipelago of Tanzania has become a low-transmission area for Plasmodium falciparum. Despite being considered an area of pre-elimination for years, achieving elimination has been difficult, likely due to a combination of imp
Externí odkaz:
https://doaj.org/article/6feb7f41f1cd4136b8f33a29805e4a19
Autor:
Prakasha Kempaiah, Karol Dokladny, Zachary Karim, Evans Raballah, John M Ong’echa, Pope L Moseley, Douglas J Perkins
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 570-584 (2016)
Abstract Severe malarial anemia (SMA; hemoglobin [Hb]
Externí odkaz:
https://doaj.org/article/c9d9af0c730a4c6b90595f9343dd34c7
Autor:
Ariel L Rivas, Mark D Jankowski, Renata Piccinini, Gabriel Leitner, Daniel Schwarz, Kevin L Anderson, Jeanne M Fair, Almira L Hoogesteijn, Wilfried Wolter, Marcelo Chaffer, Shlomo Blum, Tom Were, Stephen N Konah, Prakash Kempaiah, John M Ong'echa, Ulrike S Diesterbeck, Rachel Pilla, Claus-Peter Czerny, James B Hittner, James M Hyman, Douglas J Perkins
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e53984 (2013)
Improved characterization of infectious disease dynamics is required. To that end, three-dimensional (3D) data analysis of feedback-like processes may be considered.To detect infectious disease data patterns, a systems biology (SB) and evolutionary b
Externí odkaz:
https://doaj.org/article/4533f6e439644a68a77b469af2503ee9
Autor:
Lily E. Kisia, Qiuying Cheng, Evans Raballah, Elly O. Munde, Benjamin H. McMahon, Nick W. Hengartner, John M. Ong’echa, Kiprotich Chelimo, Christophe G. Lambert, Collins Ouma, Prakasha Kempaiah, Douglas J. Perkins, Kristan A. Schneider, Samuel B. Anyona
Publikováno v:
Tropical Medicine and Health, Vol 50, Iss 1, Pp 1-15 (2022)
Abstract Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31.1, the colony-stimulating factor 2 gene (CSF2) encodes granulocyte–macrophage colony-
Externí odkaz:
https://doaj.org/article/9181a3a765424ab5950663800c7efad4
Autor:
Beatrice M. Muriuki, Catherine S. Forconi, Peter O. Oluoch, Jeffrey A. Bailey, Anita Ghansah, Ann M. Moormann, John M. Ong’echa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Endemic Burkitt lymphoma (eBL) is an aggressive pediatric B cell lymphoma, common in Equatorial Africa. Co-infections with Epstein-Barr virus (EBV) and Plasmodium falciparum, coupled with c-myc translocation are involved in eBL etiology. Inf
Externí odkaz:
https://doaj.org/article/c8bb22471a264e9294c72f6d71cd58d1
Autor:
Lily E. Kisia, Prakasha Kempaiah, Samuel B. Anyona, Elly O. Munde, Angela O. Achieng, John M. Ong’echa, Christophe G. Lambert, Kiprotich Chelimo, Collins Ouma, Douglas J. Perkins, Evans Raballah
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Severe malarial anemia (SMA) is a leading cause of malaria-related morbidity and mortality in children. The genetic factors that influence development of SMA and inefficient erythropoiesis, a central pathogenic feature of SMA, are
Externí odkaz:
https://doaj.org/article/d64936deb1244e07876c59d122a1102c
Autor:
Nicole Caduff, Donal McHugh, Lisa Rieble, Catherine S. Forconi, John M. Ong’echa, Peter O. Oluoch, Ana Raykova, Anita Murer, Michelle Böni, Lara Zuppiger, Thomas F. Schulz, David J. Blackbourn, Obinna Chijioke, Ann M. Moormann, Christian Münz
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109056- (2021)
Summary: Herpesvirus infections shape the human natural killer (NK) cell compartment. While Epstein-Barr virus (EBV) expands immature NKG2A+ NK cells, human cytomegalovirus (CMV) drives accumulation of adaptive NKG2C+ NK cells. Kaposi sarcoma-associa
Externí odkaz:
https://doaj.org/article/8daa87608142474f9b3ea06d42a3614a
Autor:
Peter O. Oluoch, Catherine S. Forconi, Cliff I. Oduor, Dominic A. Ritacco, Hoseah M. Akala, Jeffrey A. Bailey, Jonathan J. Juliano, John M. Ong’echa, Christian Münz, Ann M. Moormann
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6711
The seroprevalence of Kaposi sarcoma-associated herpesvirus (KSHV) and the incidence of endemic Kaposi sarcoma (KS) overlap with regions of malaria endemicity in sub-Saharan Africa. Multiple studies have shown an increased risk of KSHV seroconversion
Autor:
Catherine Forconi, Anita Ghansah, Jeffrey A. Bailey, John M. Ong’echa, Peter O Oluoch, Beatrice M. Muriuki, Ann M. Moormann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Endemic Burkitt lymphoma (eBL) is an aggressive pediatric B cell lymphoma, common in Equatorial Africa. Co-infections with Epstein-Barr virus (EBV) and Plasmodium falciparum, coupled with c-myc translocation are involved in eBL etiology. Infection-in
Autor:
Priya Saikumar Lakshmi, Cliff I Oduor, Catherine S Forconi, Viriato M’Bana, Courtney Bly, Rachel M Gerstein, Juliana A Otieno, John M Ong’echa, Christian Münz, Micah A Luftig, Michael A Brehm, Jeffrey A Bailey, Ann M Moormann
Publikováno v:
Life Science Alliance. 6:e202101355
Endemic Burkitt lymphoma (BL) is a childhood cancer in sub-Saharan Africa characterized by Epstein–Barr virus and malaria-associated aberrant B-cell activation andMYCchromosomal translocation. Survival rates hover at 50% after conventional chemothe