Zobrazeno 1 - 6
of 6
pro vyhledávání: '"John M Lincecum"'
Autor:
Fernando G Vieira, Qinggong Ping, Andy J Moreno, Joshua D Kidd, Kenneth Thompson, Bingbing Jiang, John M Lincecum, Monica Z Wang, Gerard S De Zutter, Valerie R Tassinari, Beth Levine, Theo Hatzipetros, Alan Gill, Steven Perrin
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135570 (2015)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons. The mechanisms leading to motor neuron degeneration in ALS are unclear. However, there is evidence for involvement of endoplasmic r
Externí odkaz:
https://doaj.org/article/f052d1fb3a364d89b9b51dacb83c5f26
Autor:
Katherine A. High, John M. Lincecum, Brian K. Kaspar, Glen H. Nuckolls, Danilo A. Tagle, Dale Berkley, Luk H. Vandenberghe, Fulvio Mavilio, James M. Wilson, Serge Braun, Pamela J. Wernett, Cheryl L. McDonald, James McLaughlin, Jane Larkindale, Valerie Cwik, Thomas R. Cheever, Dongsheng Duan, Barry J. Byrne, Hansell H. Stedman, Katherine W. Klinger, John D. Porter, Robert H. Brown, Jeffrey S. Chamberlain, Hao Wang, Bonnie Weiss McLeod, Amelie K. Gubitz, Jerry R. Mendell, Howard J. Federoff
Publikováno v:
Human Gene Therapy
Human Gene Therapy, 2015, 26 (3), pp.127-33. ⟨10.1089/hum.2014.147⟩
Human Gene Therapy, Mary Ann Liebert, 2015, 26 (3), pp.127-33. ⟨10.1089/hum.2014.147⟩
Human gene therapy, vol 26, iss 3
Human Gene Therapy, 2015, 26 (3), pp.127-33. ⟨10.1089/hum.2014.147⟩
Human Gene Therapy, Mary Ann Liebert, 2015, 26 (3), pp.127-33. ⟨10.1089/hum.2014.147⟩
Human gene therapy, vol 26, iss 3
International audience; With recent successes in gene therapy trials for hemophilia and retinal diseases, the promise and prospects for gene therapy are once again garnering significant attention. To build on this momentum, the National Institute of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f962fe8f427bb91371406b89c94a3fc3
https://hal.science/hal-02880972
https://hal.science/hal-02880972
Autor:
Ricardo Sanchez, John M. Lincecum, Isarelis J Carrion, Joshua D. Kidd, Beth Levine, Andrew Moreno, Gerald S De Zutter, Kenneth Thompson, Alan Gill, Shawn M Sullivan, Fernando G. Vieira, Monica Z. Wang, Bashar M. Al‐Nakhala, Steven Perrin
Publikováno v:
Nature genetics. 42(5)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motor neurons. Using unbiased transcript profiling in an ALS mouse model, we identified a role for the co-stimulatory pathway, a key regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1777854e2ed27f4469ed4df7386e53
https://pubmed.ncbi.nlm.nih.gov/20348957
https://pubmed.ncbi.nlm.nih.gov/20348957
Autor:
Nancy Kelly, John M. Lincecum, James Heywood, Jeyanthi Ramasubbu, Alan Bostrom, Fernando G. Vieira, Janice E. Kranz, Sean Scott, Bashar M. Al‐Nakhala, Jill Theodoss, Jeff Cole, Kenneth Thompson
Publikováno v:
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 9(1)
Identification of SOD1 as the mutated protein in a significant subset of familial amyotrophic lateral sclerosis (FALS) cases has led to the generation of transgenic rodent models of autosomal dominant SOD1 FALS. Mice carrying 23 copies of the human S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d574462c5a43dd63d38f1e61c65069b8
https://pubmed.ncbi.nlm.nih.gov/18273714
https://pubmed.ncbi.nlm.nih.gov/18273714
Autor:
Valerie R. Tassinari, Theo Hatzipetros, Bingbing Jiang, John M. Lincecum, Alan Gill, Fernando G. Vieira, Monica Z. Wang, Joshua D. Kidd, Qinggong Ping, Gerard S. De Zutter, Andy J. Moreno, Steven Perrin, Kenneth Thompson, Beth Levine
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135570 (2015)
PLoS ONE
PLoS ONE
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons. The mechanisms leading to motor neuron degeneration in ALS are unclear. However, there is evidence for involvement of endoplasmic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ba11fec7d5ae9518a56a99747b817c
https://doi.org/10.1371/journal.pone.0135570
https://doi.org/10.1371/journal.pone.0135570
Autor:
David Riddell, Barry D. Greenberg, Diana W Shineman, Patrick J. Sweeney, Kimberly Scearce-Levie, Lorenzo M. Refolo, Jennifer L. Bizon, Iva Morse, Beth A. Hollister, Howard Fillit, Guriqbal S. Basi, Carol A. Colton, Feng Luo, Juha Yrjänheikki, Dave Morgan, Gabrielle G Leblanc, John M. Lincecum, Linda Bobbi H Lee
Publikováno v:
Alzheimer's Research & Therapy
Animal models have contributed significantly to our understanding of the underlying biological mechanisms of Alzheimer's disease (AD). As a result, over 300 interventions have been investigated and reported to mitigate pathological phenotypes or impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fb93010a020071196ad758e75c53db
https://doi.org/10.1186/alzrt90
https://doi.org/10.1186/alzrt90