Zobrazeno 1 - 5
of 5
pro vyhledávání: '"John M Leech"'
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010647 (2022)
Staphylococcus aureus persistently colonises the anterior nares of a significant proportion of the healthy population, however the local immune response elicited during S. aureus nasal colonisation remains ill-defined. Local activation of IL-17/IL-22
Externí odkaz:
https://doaj.org/article/f7b71f701b394d159a48d2c861c49246
Autor:
Aisling F Brown, Alison G Murphy, Stephen J Lalor, John M Leech, Kate M O'Keeffe, Micheál Mac Aogáin, Dara P O'Halloran, Keenan A Lacey, Mehri Tavakol, Claire H Hearnden, Deirdre Fitzgerald-Hughes, Hilary Humphreys, Jérôme P Fennell, Willem J van Wamel, Timothy J Foster, Joan A Geoghegan, Ed C Lavelle, Thomas R Rogers, Rachel M McLoughlin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005226 (2015)
Mechanisms of protective immunity to Staphylococcus aureus infection in humans remain elusive. While the importance of cellular immunity has been shown in mice, T cell responses in humans have not been characterised. Using a murine model of recurrent
Externí odkaz:
https://doaj.org/article/6832261a8fdf4af4abe77367d6c1163a
Autor:
Antonin Weckel, Miqdad O. Dhariwala, Kevin Ly, Victoria M. Tran, Oluwasunmisola T. Ojewumi, Julianne B. Riggs, Jeanmarie R. Gonzalez, Laura R. Dwyer, Joy N. Okoro, John M. Leech, Margot S. Bacino, Grace D. Cho, Geil Merana, Niroshana Anandasabapathy, Yosuke Kumamoto, Tiffany C. Scharschmidt
Publikováno v:
Immunity.
Autor:
Antonin Weckel, Miqdad O. Dhariwala, Kevin Ly, Oluwasunmisola T. Ojewumi, Julianne B. Riggs, Jeanmarie R. Gonzalez, Laura R. Dwyer, Joy N. Okoro, John M. Leech, Margot S. Bacino, Grace D. Cho, Geil Merana, Niroshana Anandasabapathy, Yosuke Kumamoto, Tiffany C. Scharschmidt
SummaryEarly life establishment of tolerance to commensal bacteria at barrier surfaces carries enduring implications for immune health but remains poorly understood. Here we show that this process is controlled by microbial interaction with a special
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43db5b07d5afa5866922d8aa7787f070
https://doi.org/10.1101/2022.06.23.497363
https://doi.org/10.1101/2022.06.23.497363
Publikováno v:
Frontiers in Immunology, Vol 4 (2014)
In apparent contrast to its invasive potential Staphylococcus aureus colonises the anterior nares of 20-80% of the human population. The relationship between host and microbe appears particularly individualised and colonisation status seems somehow p
Externí odkaz:
https://doaj.org/article/e9fbca57cff14604b5a39bb3c4a3ee44