Zobrazeno 1 - 10
of 97
pro vyhledávání: '"John M Lamar"'
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254714 (2021)
Integrin receptors for the extracellular matrix play critical roles at all stages of carcinogenesis, including tumor growth, tumor progression and metastasis. The laminin-binding integrin α3β1 is expressed in all epithelial tissues where it has imp
Externí odkaz:
https://doaj.org/article/4a7ddf358a44417baa65d2017e150d81
Publikováno v:
eLife, Vol 3 (2014)
The extracellular matrix (ECM) is a major component of tumors and a significant contributor to cancer progression. In this study, we use proteomics to investigate the ECM of human mammary carcinoma xenografts and show that primary tumors of differing
Externí odkaz:
https://doaj.org/article/ebc5483fb92845e3ba4bc7deee175b7f
Publikováno v:
Cancers, Vol 16, Iss 5, p 852 (2024)
Targeted therapies are effective cancer treatments when accompanied by accurate diagnostic tests that can help identify patients that will respond to those therapies. The YAP/TAZ-TEAD axis is activated and plays a causal role in several cancer types,
Externí odkaz:
https://doaj.org/article/7d5c9a986c8e489ba2cfddea6473e463
Publikováno v:
Cancers, Vol 15, Iss 19, p 4717 (2023)
Funding the research needed to advance our understanding of rare cancers is very challenging [...]
Externí odkaz:
https://doaj.org/article/66acb34755a74b71bcda3c70114ec8b3
Autor:
Caleb N. Seavey, Andrea Hallett, Shuo Li, Kepeng Che, Ajaybabu V. Pobbati, Shuang Ma, Ashley Burtscher, Ryan Kanai, John M. Lamar, Brian P. Rubin
Publikováno v:
Clinical Cancer Research. :OF1-OF14
Purpose: Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma caused by the WWTR1(TAZ)–CAMTA1 (TC) gene fusion. This fusion gene has been observed in almost all reported EHE cases and functions as a constitutively activated TAZ. Sequencing
Autor:
Frank B. Gertler, James E. Bear, Patricia J. Keely, Douglas A. Lauffenburger, Richard O. Hynes, Kari B. Wisinski, Michael J. Cima, Robert Langer, Duanduan Ma, Charlie Whittaker, Sreeja B. Asokan, John M. Lamar, Daisy Riquelme, Jeff Wyckoff, Bruna C. Guido, Liliane C. Broye, Tatsiana Kosciuk, Oliver Jonas, Madeleine J. Oudin
Supplementary Figure S5. Mena isoform expression does not affect Integrin alphav, beta1 or FAK levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eff0ee4083e33a04f07af4a23a9cba3
https://doi.org/10.1158/2159-8290.22531394
https://doi.org/10.1158/2159-8290.22531394
Autor:
Frank B. Gertler, James E. Bear, Patricia J. Keely, Douglas A. Lauffenburger, Richard O. Hynes, Kari B. Wisinski, Michael J. Cima, Robert Langer, Duanduan Ma, Charlie Whittaker, Sreeja B. Asokan, John M. Lamar, Daisy Riquelme, Jeff Wyckoff, Bruna C. Guido, Liliane C. Broye, Tatsiana Kosciuk, Oliver Jonas, Madeleine J. Oudin
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cccb7933131f12f4e83628ea9829270
https://doi.org/10.1158/2159-8290.22531409.v1
https://doi.org/10.1158/2159-8290.22531409.v1
Autor:
Brian P. Rubin, John M. Lamar, Ryan Kanai, Ashley Burtscher, Shuang Ma, Ajaybabu V. Pobbati, Kepeng Che, Shuo Li, Andrea Hallett, Caleb N. Seavey
Validation of the EHE cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa4f6fe91678fbd56dd33f860c1c134
https://doi.org/10.1158/1078-0432.22490690.v1
https://doi.org/10.1158/1078-0432.22490690.v1
Autor:
Brian P. Rubin, John M. Lamar, Ryan Kanai, Ashley Burtscher, Shuang Ma, Ajaybabu V. Pobbati, Kepeng Che, Shuo Li, Andrea Hallett, Caleb N. Seavey
Supplemental Table 2. Primer sequences for genotyping, qualitative reverse transcriptase-PCR, and oligonucleotides for cloning.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2b21d360d4341a413f63f2ae92dac0
https://doi.org/10.1158/1078-0432.22490681
https://doi.org/10.1158/1078-0432.22490681
Autor:
Brian P. Rubin, John M. Lamar, Ryan Kanai, Ashley Burtscher, Shuang Ma, Ajaybabu V. Pobbati, Kepeng Che, Shuo Li, Andrea Hallett, Caleb N. Seavey
Purpose:Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma caused by the WWTR1(TAZ)–CAMTA1 (TC) gene fusion. This fusion gene has been observed in almost all reported EHE cases and functions as a constitutively activated TAZ. Sequencing o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3b394673a8508677994416cbaa303d
https://doi.org/10.1158/1078-0432.c.6533195.v1
https://doi.org/10.1158/1078-0432.c.6533195.v1