Zobrazeno 1 - 10
of 52
pro vyhledávání: '"John M Humphreys"'
Publikováno v:
eLife, Vol 12 (2024)
Osmotic stress and chloride regulate the autophosphorylation and activity of the WNK1 and WNK3 kinase domains. The kinase domain of unphosphorylated WNK1 (uWNK1) is an asymmetric dimer possessing water molecules conserved in multiple uWNK1 crystal st
Externí odkaz:
https://doaj.org/article/63414f7a5ce84bc2a7aa7faabfbedafe
Publikováno v:
Infectious Disease Modelling, Vol 9, Iss 4, Pp 1175-1197 (2024)
Upon researching predictive models related to West Nile virus disease, it is discovered that there are numerous parameters and extensive information in most models, thus contributing to unnecessary complexity. Another challenge frequently encountered
Externí odkaz:
https://doaj.org/article/f32ea90e28774b5d999e0c0fcc40fc50
Modeling the 2014–2015 Vesicular Stomatitis Outbreak in the United States Using an SEIR-SEI Approach
Autor:
John M. Humphreys, Angela M. Pelzel-McCluskey, Phillip T. Shults, Lauro Velazquez-Salinas, Miranda R. Bertram, Bethany L. McGregor, Lee W. Cohnstaedt, Dustin A. Swanson, Stacey L. P. Scroggs, Chad Fautt, Amber Mooney, Debra P. C. Peters, Luis L. Rodriguez
Publikováno v:
Viruses, Vol 16, Iss 8, p 1315 (2024)
Vesicular stomatitis (VS) is a vector-borne livestock disease caused by the vesicular stomatitis New Jersey virus (VSNJV). This study presents the first application of an SEIR-SEI compartmental model to analyze VSNJV transmission dynamics. Focusing o
Externí odkaz:
https://doaj.org/article/b09361794ed04b84b72aaea8f83845c9
Autor:
John M. Humphreys, Phillip T. Shults, Lauro Velazquez-Salinas, Miranda R. Bertram, Angela M. Pelzel-McCluskey, Steven J. Pauszek, Debra P. C. Peters, Luis L. Rodriguez
Publikováno v:
Viruses, Vol 16, Iss 7, p 1118 (2024)
We conducted an integrative analysis to elucidate the spatial epidemiological patterns of the Vesicular Stomatitis New Jersey virus (VSNJV) during the 2014–15 epizootic cycle in the United States (US). Using georeferenced VSNJV genomics data, confi
Externí odkaz:
https://doaj.org/article/ce888c7ef85b4858af3b9c7c11a6ed17
Autor:
Karen M. Holcomb, Sarabeth Mathis, J. Erin Staples, Marc Fischer, Christopher M. Barker, Charles B. Beard, Randall J. Nett, Alexander C. Keyel, Matteo Marcantonio, Marissa L. Childs, Morgan E. Gorris, Ilia Rochlin, Marco Hamins-Puértolas, Evan L. Ray, Johnny A. Uelmen, Nicholas DeFelice, Andrew S. Freedman, Brandon D. Hollingsworth, Praachi Das, Dave Osthus, John M. Humphreys, Nicole Nova, Erin A. Mordecai, Lee W. Cohnstaedt, Devin Kirk, Laura D. Kramer, Mallory J. Harris, Morgan P. Kain, Emily M. X. Reed, Michael A. Johansson
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background West Nile virus (WNV) is the leading cause of mosquito-borne illness in the continental USA. WNV occurrence has high spatiotemporal variation, and current approaches to targeted control of the virus are limited, making forecasting
Externí odkaz:
https://doaj.org/article/2ee21ea30b4a49b5a774c7a9b548f0c6
Autor:
Evan C. Wilson, Stella Cousins, Dwayne R. Etter, John M. Humphreys, Gary J. Roloff, Neil H. Carter
Publikováno v:
Ecology and Evolution, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Climate change and habitat loss are recognized as important drivers of shifts in wildlife species' geographic distributions. While often considered independently, there is considerable overlap between these drivers, and understanding how the
Externí odkaz:
https://doaj.org/article/55dfb05e36ee4e1293df8f4c7e231053
Autor:
Rachel Palinski, Steven J. Pauszek, John M. Humphreys, Debra P.C. Peters, D. Scott McVey, Angela M. Pelzel‐McCluskey, Justin D. Derner, N. Dylan Burruss, Jonathan Arzt, Luis L. Rodriguez
Publikováno v:
Ecosphere, Vol 12, Iss 10, Pp n/a-n/a (2021)
Abstract Vesicular stomatitis (VS) is an arthropod‐borne viral disease that negatively impacts domestic livestock and wildlife hosts, and economically impacts both private animal owners and the commercial livestock industry. Previous phylogenetic s
Externí odkaz:
https://doaj.org/article/a7881293fc7841dc907ed9761ba5f3d2
Autor:
Julita Chlebowicz, Radha Akella, John M Humphreys, Haixia He, Ashari R Kannangara, Shuguang Wei, Bruce Posner, Elizabeth J Goldsmith
Publikováno v:
Drug Design, Development and Therapy. 17:93-105
Julita Chlebowicz,1 Radha Akella,1 John M Humphreys,1 Haixia He,1 Ashari R Kannangara,1 Shuguang Wei,2 Bruce Posner,2 Elizabeth J Goldsmith1 1Department of Biophysics, The University of Texas Southwestern Medical Center, Dallas, TX, USA; 2Department
Autor:
John M. Humphreys, Angela M. Pelzel-McCluskey, Lee W. Cohnstaedt, Bethany L. McGregor, Kathryn A. Hanley, Amy R. Hudson, Katherine I. Young, Dannele Peck, Luis L. Rodriguez, Debra P. C. Peters
Publikováno v:
Viruses, Vol 13, Iss 9, p 1811 (2021)
Mosquito-borne West Nile virus (WNV) is the causative agent of West Nile disease in humans, horses, and some bird species. Since the initial introduction of WNV to the United States (US), approximately 30,000 horses have been impacted by West Nile ne
Externí odkaz:
https://doaj.org/article/4690b0e98c4f43c9a00a44bae5305e9c
Autor:
John M. Humphreys, Katherine I. Young, Lee W. Cohnstaedt, Kathryn A. Hanley, Debra P. C. Peters
Publikováno v:
Viruses, Vol 13, Iss 5, p 934 (2021)
West Nile virus (WNV) is the most common arthropod-borne virus (arbovirus) in the United States (US) and is the leading cause of viral encephalitis in the country. The virus has affected tens of thousands of US persons total since its 1999 North Amer
Externí odkaz:
https://doaj.org/article/1933520931f84f6bbd877d159b3b206c